个人简历

工作及教育经历\r
2020-\t清华大学化学系长聘副教授、特聘研究员、博导\r
生命有机磷化学及化学生物学教育部重点实验室固定成员\r
有机光电子与分子工程教育部重点实验室固定成员\r
清华大学合成与系统生物学研究中心核心成员\r
2017-2020\t中科院长春应化所稀土资源利用国家重点实验室 研究员、博导\r
2015-2017\t荷兰格罗宁根大学、美国哈佛大学 博士后\r
2010-2015\t荷兰格罗宁根大学Zernike先进材料研究所 博士学位\r
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学术兼职\r
ACS Applied Bio Materials编委（2022-）\r
GF生物交叉领域专家（2019-）\r
科技部国家重点研发计划会评专家（2019-）\r
中国工程院院刊Engineering通讯专家/客座编辑（2019-）\r
温州市政府科技顾问（2019-）\r
中国生物物理学会纳米生物学分会委员（2019-）\r
中科院仪器装备研制项目专家（2018-）\r
中国化学会《应用化学》编委（2018-）\r
Current Nanomedicine编委（2018-）\r
吉林省青年科协理事（2018-）

研究领域

"""""发展生物合成化学技术，聚焦于高性能、可编程生物分子（核酸、蛋白）及稀土微生物杂合系统应用，主要研究方向包括：（1）发展高表达力细胞合成体系制备高强高韧生物纤维；（2）结构和界面黏附可控的生物粘合剂、紧急救治材料；（3）稀土基多模式生物成像试剂，用于癌症及神经退行性疾病诊疗；（4）生物大分子（DNA、蛋白）大规模低成本生物高效合成及其超高密度信息编码和大数据存储应用；（5）工程化稀土蛋白酶。"

近期论文

Z. Meng, Q. Liu, Y. Zhang, J. Sun, C. Yang, H. Li, M. Loznik, R. G?stl, D. Chen, F. Wang*, N. A. Clark, H. Zhang, A. Herrmann*, K. Liu*, Highly stiff and stretchable DNA liquid crystalline organogels with super plasticity, ultrafast self-healing and magnetic response behaviors, Adv. Mater. 2021, 33, 2106208.\r
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J. Sun, L. Xiao, B. Li, K. Zhao, Z. Wang, Y. Zhou, C. Ma, J. Li, H. Zhang, A. Herrmann*, K. Liu*, Genetically engineered polypeptide adhesive coacervates for surgical applications, Angew. Chem. Int. Ed., 2021, 60, 23687.\r
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L. Xiao, Z. Wang, Y. Sun, B. Li, B. Wu, C. Ma, V. S. Petrovskii, X. Gu, D. Chen, I. I. Potemkin, A. Herrmann, H. Zhang, K. Liu*, An artificial phase‐transitional underwater bioglue with robust and switchable adhesion performance, Angew. Chem. Int. Ed. 2021, 60, 12082.\r
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C. Ma, B. Li, J. Zhang, Y. Sun, J. Li, H. Zhou, J. Shen, R. Gu, J. Qian, C. Fan, H. Zhang, K. Liu*, Significantly improving the bioefficacy for rheumatoid arthritis with supramolecular nanoformulations, Adv. Mater. 2021, 33, 2100098.\r
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S. Wang, B. Li, H. Zhang, J. Chen, X. Sun, J. Xu, T. Ren, Y. Zhang, C. Ma*, W. Guo*, K. Liu*, Improving Bioavailaibity of Hydrophobic Prodrugs through Supramolecular Nanocarriers based on Recombinant Proteins for Osteosarcoma Treatment, Angew. Chem. Int. Ed. 2021, 60, 11252.\r
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C. Ma, J. Sun, B. Li, Y. Feng, Y. Sun, L. Xiang, B. Wu, L. Xiao, B. Liu, V. S. Petrovskii, B. Liu, J. Zhang, Z. Wang, H. Li, L. Zhang, J. Li, F. Wang, R. Gostl, I. I. Potemkin, D. Chen, H. Zeng, H. Zhang, D. Weitz, K. Liu*, A. Herrmann*, Ultra-strong bio-glue from genetically engineered polypeptides, Nat. Commun. 2021, 12, 3613.\r
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J. Sun, C. Ma, S. Maity, F. Wang, Y. Zhou, G. Portale, R. G?stl, W. H. Roos, H. Zhang, K. Liu*, A. Herrmann*, Reversibly photo-modulating mechanical stiffness and toughness of bioengineered protein fibers, Angew. Chem. Int. Ed. 2021, 60, 3222.\r
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J. Sun, C. Ma, B. Li, F. Wang, K. Liu*, H. Zhang, Proteinaceous fibers with outstanding mechanical properties manipulated by supramolecular interactions, CCS Chem. 2020, 2, 1669.\r
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C. Ma, B. Li, B. Shao, B. Wu, D. Chen, J. Su*, H. Zhang, K. Liu*, Anisotropic protein organofibers encoded with extraordinary mechanical behaviors for cellular mechanobiology applications, Angew. Chem., Int. Ed. 2020, 59, 21481.\r
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C. Ma, J. Dong, M. Viviani, I. Tulini, N. Pontillo, S. Maity, Y. Zhou, W. H. Roos, K. Liu*, A. Herrmann*, G. Portale*, Denovo rational design of a freestanding, supercharged polypeptide, proton conducting membrane, Sci. Adv. 2020, 6, eabc0810.\r
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J. Li#, Y. Sun#, Y. Liang#, J. Ma*, B. Li, C. Ma, R. Tanzi, H. Zhang, K. Liu*, C. Zhang*, Extracellular elastin molecule modulates Alzheimer’s Aβ dynamics in vitro and in vivo by affecting microglial activities, CCS Chem. 2020, 2, 1830.\r
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B. Shao, S. Wan, C. Yang, J. Shen, Y. Li, H. You, D. Chen*, C. Fan, K. Liu*, H. Zhang*, Engineered Anisotropic Fluids of Rare Earth Nanomaterials, Angew. Chem., Int. Ed. 2020, 59, 18213.\r
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Y. Zhang, L. Kong, F. Wang, B. Li, C. Ma, D. Chen*, K. Liu*, C. Fan, H. Zhang, Information stored in nanoscale: encoding data in a single DNA strand with Base64, Nano Today 2020, 33, 100871.\r
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Y. Li, J. Li, J. Sun, H. He, B. Li, C. Ma, K. Liu*, H. Zhang, Bio-inspired and Mechanically Strong Fibers Based on Engineered Non-Spider Chimeric Proteins, Angew. Chem. Int. Ed. 2020, 59, 8148.\r
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J. Li, B. Li, J. Sun, C. Ma, S. Wan, Y. Li, R. G?stl, A. Herrmann, K. Liu*, H. Zhang, Engineered Near-Infrared Fluorescent Protein Assemblies for Robust Bioimaging and Therapeutic Applications, Adv. Mater. 2020, 32, 2000964.\r
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H. He, C. Yang, F. Wang*, Z. Wei, J. Shen, D. Chen, C. Fan, H. Zhang, K. Liu*, Mechanically strong globular protein-based fibers via microfluidic spinning technique, Angew. Chem. Int. Ed. 2020, 59, 4344.\r
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Z. Sun, C. Yang, F. Wang, B. Wu, B. Shao, Z. Li, D. Chen*, Z. Yang*, K. Liu*, Biocompatible and pH‐Responsive Colloidal Surfactants with Tunable Shape for Controlled Interfacial Curvature, Angew. Chem. Int. Ed. 2020, 59, 9365.\r
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C. Ma, J. Su, B. Li, A. Herrmann, H. Zhang, K. Liu*, Solvent-free plasticity and programmable mechanical behaviors of engineered proteins, Adv. Mater. 2020, 32, 1907697.\r
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J. Sun, J. Su, C. Ma, R. G?stl, A. Herrmann, K. Liu*, H. Zhang,Fabrication and mechanical properties of engineered protein-based adhesives and fibers, Adv. Mater. 2020, 32, 1906360.\r
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C.Ma, J. Su, Y. Sun, Y. Feng, N. Shen, B. Li, Y. Liang, X. Yang, H. Wu, H. Zhang, A. Herrmann*, R. E. Tanzi, K. Liu*, C. Zhang*, Significant upregulation of Alzheimer’s β-amyloids in vivo induced by extracellular elastin polypeptides, Angew. Chem. Int. Ed. 2019, 58, 18703.\r
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H. He, K. Zhao, L. Xiao, Y. Zhang, Y. Cheng, S. Chen, L. Zhang*, X. Zhou*, K. Liu*, H. Zhang, Detection and chiral recognition of α-hydroxyl acid through proton and CEST NMR using Yb macrocyclic complex, Angew. Chem. Int. Ed. 2019, 58, 18286.\r
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L. Zhang, C. Ma, J. Sun, B. Shao, D. Chen, G. Portale, K. Liu*, A. Herrmann*, Genetically engineered supercharged polypeptide fluids: fast and persistent self-ordering induced by a touch, Angew. Chem. Int. Ed. 2018. 57, 6878.