个人简历

个人经历\r
1995.09-1999.07 清华大学生物科学与技术系 理学学士\r
1999.09-2005.01 清华大学生物科学与技术系 生物学博士\r
2005.04-2009.07 美国杜克大学细胞生物学系 博士后（research associate）\r
2009.12-2016.12 清华大学环境学院 副教授\r
2017.01-2021.12 清华大学环境学院 特别研究员\r
2022.01至今 清华大学环境学院 长聘副教授\r
国家环境保护环境微生物利用与安全控制重点实验室常务副主任，钢铁工业环境保护国家重点实验室学术委员会委员，中国环境科学学会水处理与回用专业委员会委员，中国环境科学学会环境医学与健康分会会员，中国毒理学会环境与生态毒理专业委员会会员，日本水环境学会国际会员\r
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荣誉奖励\r
2021年，《水处理生物学》第七版获得北京高校“优质本科教材课件”重点项目。\r
2021年，“环境工程微生物学”课程获得清华大学精品课程。\r
2018年，获国家级教学成果奖二等奖，“多层次构建全球环境人才培养体系，全方位提升学生国际胜任力”，第9获奖人。\r
2017年，获北京市高等教育教学成果奖一等奖，“多层次构建全球环境人才培养体系，全方位提升学生国际胜任力”，第9获奖人。\r
2017年，JSWE-IDEA Water Environment International Exchange Award.\r
2016年，《水处理生物学》第五版获得清华大学优秀教材特等奖。\r
2016年，获中国环境科学学会第十一届“优秀环境科技工作者奖”。\r
2015年，获宝钢优秀教师奖。\r
2014年，获中国环境保护部“国家环境保护专业技术青年拔尖人才”称号。\r
2010年，获中国环境科学学会第七届“青年科技奖”。\r
2003年，获教育部科学技术一等奖，第三完成人。

研究领域

"学术方向为环境毒理与健康，是生物学与环境污染控制科学紧密结合的交叉学科，目前专注于水质安全。本人利用动物模型和分子生物学手段，从生物毒性和致病性角度识别新兴污染物及其毒性作用机理，研究水处理过程中污染物毒性的去除与转化，病原微生物环境赋存、变异、传播和控制，确定基于健康风险的污染物阈值，为水质安全保障提供控制目标和理论支撑。"

近期论文

Wei FQ, Lu Y, Shi Q, Chen Z, Li K-X, Zhang T, Shi Y-L, Xu Q, Hu H-Y. A dose optimization method of disinfection units and synergistic effects of combined disinfection in pilot tests. Water Research, in press.\r
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Chen M, Shi L, Liu G, Wu X, Lu Y*. Aerosol exposure assessment during reclaimed water utilization in China and risk evaluation in case of Legionella. Frontiers of Environmental Science and Engineering, 2022, 16(7): 95\r
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Liu G, Lu Y*, Shi L, Kong J, Hu H, Liu W. Trace endotoxin in reclaimed water is only one of the risk sources in subchronic inhalation exposure. Environmental Pollution, 2021, 285:117479.\r
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Kong J, Lu Y*, Ren Y, Chen Z, Chen M. The virus removal in UV irradiation, ozonation and chlorination. Water Cycle, 2021, 2:23-31.\r
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Shi X, Liu G, Shi L, Chen M, Wu X, Zhao J, Lu Y*. The detection efficiency of digital PCR for the virulence genes of waterborne pathogenic bacteria. Water Supply, 2021, 21(5SI):2285-2297.\r
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吴效晋，刘刚，胡洪营，陆韻*。环介导等温扩增检测水源病原菌，环境工程，https://kns.cnki.net/kcms/detail/11.2097.x.20201229.1112.004.html。\r
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史亮亮，陆韻*，陈梦豪，刘刚。再生水病原微生物基准对检测的指导意义，环境工程，2021， 39(3):8-14。\r
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Liu G, Lu Y*, Shi L, Ren Y, Kong J, Zhang M, Chen M, Liu W. TLR4-MyD88 signaling pathway is responsible for acute lung inflammation induced by reclaimed water. Journal of Hazardous Materials, 2020, 396:122586. (1)\r
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Shi X, Liu G, Zhang M, Zhao J, Li H, Yang Z, Bai H, Liang P, Lu Y*. Membrane Sensitive Bacterial DNA Extractions and Absolute Quantitation of Recovery Efficiencies. Science of the Total Environment, 2020, 708:135125. (0)\r
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Wu, QY*, Yang, LL, Zhang, XY, Wang, WL, Lu, Y, Du, Y, Lu, Y, Hu, HY. Environmental Science & Technology, 2020, 54(14):8926-8937.\r
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Dao, GH, Wang, SN, Wang, XX, Chen, Z, Wu, YH, Wu, GX, Lu, Y, Liu, SM, Hu, HY*. Enhanced Scenedesmus sp. growth in response to gibberellin secretion by symbiotic bacteria. Science of Total Environment, 2020, 740:140099.\r
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Shi, XJ, Chen, Z*, Lu, Y, Shi, Q, Wu, YH, Hu, HY. Significant increase of assimilable organic carbon (AOC) levels in MBR effluents followed by coagulation, ozonation and combined treatments: Implications for biostability control of reclaimed water. Frontiers of Environmental Science and Engineering, 2020, 15(4):68.\r
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Cui Q, Liu, H, Yang, HW, Lu, Y, Chen, Z*, Hu, HY*. Bacterial removal performance and community changes during advanced treatment process: A case study at a full-scale water reclamation plant. Science of Total Environment, 2020, 705:135811.\r
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Liu LH, Zhou XH*, Lu Y, Shi HC, Ma M, Yu T. Triple functional small-molecule-protein conjugate mediated optical biosensor for quantification of estrogenic activities in water samples. Environmental International, 2019, 132, 105091.\r
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Xue J#, Zhang J#, Qiao J*, Lu Y*. Effects of chlorination and combined UV/Cl2 treatment on endotoxin activity and inhalation toxicity of lipopolysaccharide, gram-negative bacteria and reclaimed water. Water Research, 2019, 155:124-130. (6)\r
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Ren Y, Kong J, Xue J, Shi X, Li H, Qiao J*, Lu Y*. Effects of ozonation on the activity of endotoxin and its inhalation toxicity in reclaimed water. Water Research, 2019, 154:153-161. (8)\r
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Du Y, Wu QY*, Lv XT, Ye B, Zhan XM, Lu Y, Hu HY*. Electron donating capacity reduction of dissolved organic matter by solar irradiation reduces the cytotoxicity formation potential during wastewater chlorination. Water Research, 2018, 145:94-102.\r
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Du Y, Wu QY*, Lv XT, Wang QP, Lu Y, Hu HY*. Exposure to solar light reduces cytotoxicity of sewage effluents to mammalian cells: Roles of reactive oxygen and nitrogen species. Water Research, 2018, 143:570-578.\r
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Huo ZY, Li GQ, Yu T, Lu Y, Sun H, Wu YH, Yu C, Xie X*, Hu HY*. Impact of water quality parameters on bacteria inactivation by low-voltage electroporation: mechanism and control. Environmental Science-Water Research & Technology, 2018, 4(6):872-881.\r
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Chen Z, Yu T, Ngo HH, Lu Y, Li GQ, Wu QY, Li KX, Bai Y, Liu SM, Hu HY*. Assimilable organic carbon (AOC) variation in reclaimed water: Insight on biological stability evaluation and control for sustainable water reuse. Bioresource Technology, 2018, 254:290-299.\r
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Feng Y, Ren Z, Wu F, Reichert A, Lu Y*. Optimization of the gram staining method based on superparamagnetic magnetic nanobeads. Journal of Environmental Accounting and Management, 2018, 6(3):263-271. (0)\r
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Yu T, Sun H, Chen Z, Wang Y-H, Huo Z-Y, Ikuno N, Ishii K, Jin Y, Hu H-Y, Wu Y-H*, Lu Y*. Different bacterial species and their extracellular polymeric substances (EPSs) significantly affected reverse osmosis (RO) membrane fouling potentials in wastewater reclamation. Science of the Total Environment, 2018, 644:486-493. (10)\r
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Li G-Q, Huo Z-Y, Wu Q-Y, Lu Y*, Hu H-Y*. Synergistic effect of combined UV-LEDs and chlorine treatment on Bacillus Subtilis spores inactivation. Science of the Total Environment, 2018, 639:1233-1240. (17)\r
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Xue J, Zhang J, Wu Q-Y*, Lu Y*. Sub-chronic inhalation of reclaimed water-induced fibrotic lesion in a mouse model. Water Research, 2018, 139:240-251. (10)\r
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Chen Z, Yu T, Ngo HH, Lu Y, Li G, Wu Q, Li K, Bai Y, Liu S, Hu HY*. Assimilable organic carbon (AOC) variation in reclaimed water: Insight on biological stability evaluation and control for sustainable water reuse. Bioresource Technology, 2018, 254:290-299.\r
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Xu B, Li K, Qiao J, Liungai Z, Chen C*, Lu Y*. UV photoconversion of environmental oestrogen diethylstilbestrol and its persistence in surface water under sunlight. Water Research, 2017, 127:77-85. (6)\r
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Li GQ; Wang WL; Huo ZY; Lu Y*; Hu HY*. Comparison of UV-LED and low pressure UV for water disinfection: photoreactivation and dark repair of Escherichia coli. Water Research, 2017, 126:134-143. (66)\r
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Lv XT, Zhang X, Du Ye, Wu QY*, Lu Y*, Hu HY. Solar light irradiation significantly reduced cytotoxicity and disinfection byproducts in chlorinated reclaimed water. Water Research, 2017, 126:162-169. (23)\r
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Li GQ, Yu T, Wu QY, Lu Y*, Hu HY*. Development of an ATP luminescence-based method for assimilable organic carbon determination in reclaimed water. Water Research, 2017, 123:345-352. (17)\r
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Liu L, Zhou X*, Lu Y*, Shan D, Xu B, He M, Shi H, Qian Y. Facile screening of potential xenoestrogens by an estrogen receptor-based reusable optical biosensor. Biosensors and bioelectronics, 2017, 97:16-20. (22)\r
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Wang WL, Wu QY*, Li ZM, Lu Y, Du Y, Wang T, Huang N, Hu HY*. Light-emitting diodes as an emerging UV source for UV/chlorine oxidation: Carbamazepine degradation and toxicity changes. Chemical Engineering Journal, 2017, 310:148-156.\r
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Du Y, Wu QY*, Lu Y, Hu HY*, Yang Y, Liu R, Liu F. Increase of cytotoxicity during wastewater chlorination: Impact factors and surrogates. Journal of Hazardous Materials, 2017, 324:681-690.\r
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Yu T, Meng L, Zhao Q-B, Shi Ye, Hu H-Y, Lu Y*. Effects of chemical cleaning on RO membrane inorganic, organic and microbial foulant removal in a full-scale plant for municipal wastewater reclamation. Water Research, 2017, 113:1-10. (42)\r
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Yu T*, Li GQ, Lin WQ, Hu H-Y, Lu Y*. Coagulation increased the growth potential of various species bacteria of the effluent of a MBR for the treatment of domestic wastewater. Environmental Science and Pollution Research, 2017, 24(6):5126-5133. (10)\r
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Huo ZY, Xie X*, Yu T, Lu Y, Feng C, Hu HY*. Nanowire-Modified Three-Dimensional Electrode Enabling Low-Voltage Electroporation for Water Disinfection. Environmental Science & Technology, 2016, 50(14):7641-7649.\r
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Xue J, Zhang J, Xu B, Xie J, Wu W, Lu Y*. Endotoxins: the critical risk factor in reclaimed water via inhalation exposure. Environmental Science & Technology, 2016, 50:11957-11964. (13)\r
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Duan R, Lu Y*, Hou L, Du L, Sun L, Tang X. U-shaped microRNA expression pattern could be a new concept biomarker for environmental estrogen. Frontiers of Environmental Science & Engineering, 2016, 10(6):11. (6)\r
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Li M, Xu B, Liungai Z, Hu H-Y, Qiao J*, Lu Y*. The removal of estrogenic activity with UV/chlorine technology and identification of novel estrogenic disinfection by-products. Journal of Hazardous Materials, 2016, 307:119-126. (26)\r
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Zhang J, Xue J, Xu B, Xie J, Qiao J*, Lu Y*. Inhibition of Lipopolysaccharide Induced Acute Inflammation in Lung by Chlorination. Journal of Hazardous Materials, 2016, 303:131-136. (14)\r
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Yang Y, Lu Y*, Wu QY, Hu H-Y*, Chen YH, Liu WL. Evidence of ATP assay as an appropriate alternative of MTT assay for cytotoxicity of secondary effluents from WWTPs. Ecotoxicology and Environmental Safety, 2015, 122:490-496. (26)\r
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Shang G, Xue J, Li M, Hu H-Y, Lu Y*. Estrogen receptor affinity chromatography: a new method for characterization of novel estrogenic disinfection by-products. Chemosphere, 2014, 104:251-257. (12)\r
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Xue J#, Shang G#, Tanaka Y, Saihara Y, Hou L, Velasquez N, Liu W, Lu Y*. Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water, BMC Complementary and Alternative Medicine, 2014, 14:81. (13)\r
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Wu Y-H, Hu H-Y*, Yu Y, Zhang T-Y, Zhu S-F, Zhuang L-L, Zhang X, Lu Y. Microalgal species for sustainable biomass/lipid production using wastewater as resource: A review. Renewable and Sustainable Energy Reviews, 2014, 33:675-688.\r
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Hou LY, Lu Y*, Li Y, Li L. MiRNA-451 is a potential biomarker for estrogenicity in mouse uterus. Frontiers of Environmental Science and Engineering, 2014, 8(1):99-105.\r
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Liu KC, Jiang M, Lu Y, Chen H, Sun J, Wu SP, Ku WY, Nakagawa H, Kita Y, Natsugoe S, Peters JH, Rustgi AK, Onaitis MW, Kiernan A, Chen XX, Que JW*. Sox2 Cooperates with Inflammation-Mediated Stat3 Activation in the Malignant Transformation of Foregut Basal Progenitor Cells. Cell Stem Cell, 2013, 12(3):304-315.\r
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Xue J, Lu Y*, Velasquez N, Yu R-Z, Hu H-Y, Liu Z-T, Meng W. Introduction of risk size in the determination of un47. Xu, X; Rock, JR; Lu, Y; Futtner, C; Schwab, B; Guinney, J; Hogan, BLM; Onaitis, MW*. Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma. PNAS, 2012, 109(13): 4910-4915.\r
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Huang J-J, Hu H-Y*, Wu YH, Wei B, Lu Y. Effect of chlorination and ultraviolet disinfection on tetA-mediated tetracycline resistance of Escherichia coli. Chemosphere, 2012, 90(8):2247-2253.\r
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Huang J-J, Hu H-Y*, Lu SQ, Li Y, Tang F, Lu Y, Wei B. Monitoring and evaluation of antibiotic-resistant bacteria at a municipal wastewater treatment plant in China. Environmental International, 2012, 42:31-36.\r
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Huang J-J, Hu H-Y*, Tang F, Li Y, Lu SQ, Lu Y. Inactivation and reactivation of antibiotic-resistant bacteria by chlorination in secondary effluents of a municipal wastewater treatment plant. Water Research, 2011, 45(9):2775-2781.\r
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Lu Y#, Futtner C#, Rock JR, Xu X, Whitworth W, Hogan BLM, Onaitis MW*. Evidence that SOX2 overexpression is oncogenic in the Lung. Plos One 2010;5:-. (IF 3.234) (150)\r
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Lu Y*, Hou L, Hu H-Y, Li L. Progress in toxicogenomics. Ecology and Environmental Sciences, 2010, 19(9):2232-2239.\r
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Rock JR, Onaitis MW, Rawlins EL, Lu Y, Clark CP, Xue Y, Randell SH, Hogan BLM*. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proceedings of the National Academy of Sciences of the United States of America 2009;106:12771-12775.\r
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Erhunmwunsee L, Lu Y, Luo XY, Harpole DH, Hogan BLM, Onaitis MW*. Basal cells in lung cancer. Journal of the American college of surgeons, 2008, 207(3):S30-S30.\r
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Lu Y, Thomson JM, Wong HY, Hammond SM, Hogan BL*. Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol. 2007 Oct 15;310(2):442-53. Epub 2007 Aug 9. (371)\r
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Zhang G, Lu H, Lu Y, Jiang S, Chen YH*. Neutralization of HIV-1 primary isolate by ELDKWA-specific murine monoclonal antibodies. Immunobiology. 2005;210(9):639-45.\r
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Liu W, Zou P, Ding J, Lu Y, Chen YH*. Sequence comparison between the extracellular domain of M2 protein human and avian influenza A virus provides new information for bivalent influenza vaccine design. Microbes Infect. 2005 Feb;7(2):171-7. Epub 2004 Dec 25.\r
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Liu W, Peng Z, Liu Z, Lu Y, Ding J, Chen YH*. High epitope density in a single recombinant protein molecule of the extracellular domain of influenza A virus M2 protein significantly enhances protective immunity. Vaccine. 2004 Dec 2;23(3):366-71.\r
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Lu Y, Chen YH*. Spike protein homology between the SARS-associated virus and murine hepatitis virus implies existence of a putative receptor-binding region. Chinese Science Bulletin, 2003, 48(11):1115-1117 (3)\r
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Liu WL, Lu Y, Chen YH*. Bioinformatics analysis of SARS-CoV M protein provides information for vaccine development. Progress in Natural Science, 2003, 13(11):844-847\r
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Lu Y, Ding J, Liu WL, Chen YH*. A candidate vaccine against influenza virus intensively improved the immunogenicity of a neutralizing Epitope. International Archives of Allergy and Immunology, 2002, 127(3):245-250 (11)\r
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Lu Y, Ding J, Chen YH*. Immunogenicity and specificity of the candidate multi-epitope-vaccines against HIV-1. Immunopharmacology and Immunotoxicology, 2001, 23(4):487-494 (11)\r
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Xiao Y, Lu Y, Chen YH*. Epitope-vaccine as a new strategy against HIV-1 mutation. Immunology Letters, 2001, 77:3-6\r
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Ding J, He F, Lu Y, Xiao Y, Chen YH*. Induction of multi-epitope-specific antibodies against HIV-1 by multi-epitope-vaccines. Chinese Science Bulletin, 2001, 46(22):1859-1864\r
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Yang HW, Xiao Y, Lu Y, Chen YH*. Characterization of interaction between C-domain on HIV-1 gp41 and the putative receptor protein p62. Immunobiology, 2001, 203(5):778-785\r
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Lu Y, Xiao Y, Ding J, Dierich MP, Chen YH*. Immunogenicity of neutralizing epitopes on multiple-epitope- vaccines against HIV-1. International Archives of Allergy and Immunology, 2000, 121(1):80-84 (20)\r
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Lu Y, Ding J, Xiao Y, Chen Y*. Multi-epitope-vaccines intensively increased levels of antibodies recognizing three neutralizing epitopes on HIV –1 envelop protein. Scandinavian Journal of Immunology, 2000, 51(5):497-501 (20)\r
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Liao MF, Lu Y, Xiao Y, Dierich MP, Chen YH*. Induction of high level of specific antibody response to the neutralizing epitope ELDKWA on HIV-1 gp41 by peptide-vaccine. Peptides, 2000, 21(4):463-468\r
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Ding J, Lu Y, Chen YH*. Candidate multi-epitope-vaccines in aluminium adjuvant induce high levels of antibodies with predefined multi-epitope-specificity against HIV-1. FEMS Immunology and Medical Microbiology 2000, 29(2):123-127\r
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Xiao Y, Liao MF, Lu Y, Dierich MP, Chen YH*. Epitope-vaccines:A new strategy to induce high levels of neutralizing antibodies against HIV-1. Immunobiology, 2000, 201(3-4):323-331\r
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Xiao Y, Zhao YX, Lu Y, Chen YH*. Epitope-vaccine induced high levels of ELDKWA-epitope-specific neutralizing antibody. Immunological Investigation, 2000, 29(1):41-50