个人简历
1991.9－1996.7 山西医科大学，医学学士\r1997.9－2000.7 山西医科大学，医学硕士\r2000.9－2003.7 中国协和医科大学基础医学研究所，理学博士\r2004.8－2010.12 北京生命科学研究所\r2011.1－至今 清华大学生命科学学院
研究领域
"植物受体激酶的结构生物学研究"
近期论文
Song W, Liu L, Wang J, Wu Z, Zhang H, Tang J, Lin G, Wang Y, Wen X, Li W, Han Z*, Guo H*, Chai J*.Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth. Cell research 26, 674-685, (2016).\r\rSong W*, Wang J*, Han Z*, Zhang Y, Zhang H, Wang W, Chang J, Xia B, Fan S, Zhang D, Wang J, Wang HW, Chai J. Structural basis for specific recognition of single-stranded RNA by Toll-like receptor 13. Nature structural & molecular biology 22, 782-787, (2015).\r\rHan Z, Sun Y, Chai J.Structural insight into the activation of plant receptor kinases. Current opinion in plant biology 20, 55-63, (2014).\r\rSun Y, Li L, Macho AP, Han Z*, Hu Z, Zipfel C, Zhou JM*, Chai J*. Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex. Science 342, 624-628, (2013).\r\rSun Y*, Han Z*, Tang J, Hu Z, Chai C, Zhou B, Chai J. Structure reveals that BAK1 as a co-receptor recognizes the BRI1-bound brassinolide. Cell research 23, 1326-1329, (2013).\r\rGao H, Wu X, Chai J, Han Z*.Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region. Cell research 22, 1716-1720, (2012).\r\rShe J*, Han Z*, Kim TW, Wang J, Cheng W, Chang J, Shi S, Wang J, Yang M, Wang ZY, Chai J.Structural insight into brassinosteroid perception by BRI1. Nature 474, 472-476, (2011).\r\rHan Z*, Niu T*, Chang J, Lei X, Zhao M, Wang Q, Cheng W, Wang J, Feng Y, Chai J.Crystal structure of the FTO protein reveals basis for its substrate specificity. Nature 464, 1205-1209, (2010).\r\rHan Z, Xing X, Hu M, Zhang Y, Liu P, Chai J. Structural basis of EZH2 recognition by EED. Structure 15, 1306-1315, (2007).\r\rHan Z, Guo L, Wang H, Shen Y, Deng XW, Chai J. Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5. Molecular cell 22, 137-144, (2006).
