个人简历
2011-至今 清华大学医学院生物医学工程系研究员 2007-2011 美国杜克大学生物医学工程系研究助理 2005-2007 日本京都大学化学研究所COE研究员 2000-2004 北京大学化学与分子工程学院，高分子化学与物理专业博士 1997-2000 青岛化工学院，材料加工专业硕士 1993-1997 青岛化工学院，橡胶工程专业学士
研究领域
生物材料：设计基因工程多肽、功能高分子、蛋白质偶联物，并将其用于药物/生物大分子递送、分子影像/诊断、细胞与组织工程等生物医药领域。纳米医学：设计智能纳米药物，并将其用于癌症、糖尿病、传染病、心血管病等重大疾病的诊疗。
近期论文
22.Wenguo Zhao, Jin Hu, Weiping Gao*. Glucose oxidase-polymer nanogels for synergistic cancer-starving and oxidation therapy. ACS Appl. Mater. Interfaces 2017, DOI: 10.1021/acsami.7b06814 21.Guilin Wang, Jin Hu, Weiping Gao*. Tuning the molecular size of site-specific interferon-polymer conjugate for optimized antitumor efficacy. SCIENCE CHINA Materials 2017, 60, 563-570. Note: This paper is an invited letter for SPECIAL ISSUE: Biomaterials for Therapeutic Delivery. 20.Mengmeng Sun, Dong Peng, Hanjun Hao, Jin Hu, Dongliang Wang, Kun Wang, Jing Liu, Ximin Guo, Yen Wei, Weiping Gao*. Thermally triggered in situ assembly of gold nanoparticles for cancer multimodal imaging and photothermal therapy. ACS Appl. Mater. Interfaces 2017, 9, 10453-10460. 19.Linjia Su, Song Hu, Li Zhang, Zhuoran Wang, Weiping Gao, Jing Yuan*, Minghua Liu*. A fast and efficient replacement of CTAB with MUA on the surface of gold nanorods assisted by a water-immiscible ionic liquid. Small 2017, 13, 1602809. 18.Xinyu Liu, Weiping Gao*. In situ growth of self-assembled protein-polymer nanovesicles for enhanced intracellular protein delivery. ACS Appl. Mater. Interfaces 2017, 9, 2023-2028. 17.Jin Hu, Guilin Wang, Wenguo Zhao, Weiping Gao*. In situ growth of a C-terminal interferon-alpha conjugate of a phospholipid polymer that outperforms PEGASYS in cancer therapy.J. Control. Release 2016, 237, 71-77. 16.Jin Hu, Guilin Wang, Wenguo Zhao, Xinyu Liu, Libin Zhang, Weiping Gao*. Site-specific in situ growth of an interferon-polymer conjugate that outperforms PEGASYS in cancer therapy. Biomaterials 2016, 96, 84-92. Note: This paper has been highlighted by Tsinghua News. 15.Mengmeng Sun, Fei Liu, Yukun Zhu, Wansheng Wang, Jin Hu, Jing Liu, Zhifei Dai, Kun Wang, Yen Wei, Jing Bai, Weiping Gao*. Salt-induced Aggregation of Gold nanoparticles for photoacoustic imaging and photothermal therapy of cancer. Nanoscale 2016, 8， 4452-4457. 14.Jin Hu, Guilin Wang, Xinyu Liu, Weiping Gao*. Enhancing pharmacokinetics, tumor accumulation and antitumor efficacy by elastin-like polypeptide fusion of interferon alpha. Adv. Mater. 2015, 27, 7320-7324. Note: This paper has been highlighted by Science China Materials, X-MOL and Tsinghua News. 13.Libin Zhang, Wenguo Zhao, Xinyu Liu, Guilin Wang, Yang Wang, Dong Li, Liangzhi Xie, Yan Gao, Haiteng Deng, Weiping Gao*. Site-selective in situ growth of fluorescent polymer-antibody conjugates with enhanced antigen detection by signal amplification. Biomaterials 2015, 64, 2-9. Note: This paper has been highlighted by Tsinghua News. 12.Jin Hu, Lining Xie, Wenguo Zhao, Mengmeng Sun, Xinyu Liu, Weiping Gao*. Design of tumor-homing and pH-responsive polypeptide-doxorubicin nanoparticles with enhanced anticancer efficacy and reduced side effects. Chem. Commun. 2015, 51, 11405-11408. 11.Wenguo Zhao, Fei Liu, Yue Chen, Jing Bai, Weiping Gao*. Synthesis of well-defined protein-polymer conjugates for biomedicine. Polymer 2015, 66, A1-A10. Note: This paper is an invited review paper and feature article, selected as a cover article of the journal. 10.Liao Peng, Huijuan Zhang, Anchao Feng, Meng Huo, Zilin Wang, Jin Hu, Weiping Gao and Jinying Yuan. Electrochemical redox responsive supramolecular self-healing hydrogels based on host-guest interaction. Polym. Chem. 2015, 6, 3652-3659. 9.Jin Hu, Wenguo Zhao, Yan Gao, Mengmeng Sun, Yen Wei, Haiteng Deng, Weiping Gao*. Site-specific in situ growth of a cyclized protein-polymer conjugate with improved stability and tumor retention. Biomaterials 2015, 47, 13-19. 8.Bo-wen Liu, Hang Zhou, Si-tong Zhou, Hui-juan Zhang, An-chao Feng, Chun-mei Jian, Jin Hu, Wei-ping Gao, Jin-ying Yuan. Synthesis of Self-Assembly of CO2-Temperature Dual Stimuli-Responsive Triblock Copolymers. Macromolecules 2014, 47, 2938-2946. 7.Liao Peng, Anchao Feng, Huijuan Zhang, Hong Wang, Chunmei Jian, Bowen Liu, Weiping Gao, Jinying Yuan. Votage-responsive micelles based on the assembly of two biocompatible homopolymers. Polym. Chem. 2014, 5, 1751-1759. 6.Yizhi Qi, Miriam Amiram, Weiping Gao, Dewey McCafferty, and Ashutosh Chilkoti. Sortase-Catalyzed Initiator Attachment Enables High Yield Growth of a Stealth Polymer from the C Terminus of a Protein. Macromol. Rapid Commun. 2013, 34, 1256-1260. 5.Weiping Gao, Donghua Xu, Dong Woo Lim, Stephen L. Craig, Ashutosh Chilkoti. In situ growth of a thermoresponsive polymer of a genetically engineered elastin-like polypeptide. Polym. Chem. 2011, 2，1561-1566. 4.Weiping Gao, Wenge Liu, Trine Christensen, Michael R. Zalutsky, Ashutosh Chilkoti. In situ growth of a PEG-like polymer from the C-terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation. Proc. Natl. Acad. Sci. USA 2010, 107, 16432-16437. Note: This paper has been highlighted by Nature and Science-Business eXchange (SciBX). 3.Weiping Gao, Wenge Liu, J. Andrew Mackay, Michael R. Zalutsky, Eric J. Toone, Ashutosh Chilkoti. In situ growth of a stoichiometric PEG-like conjugate at a protein’s N-terminus with significantly improved pharmacokinetics. Proc. Natl. Acad. Sci. USA 2009, 106, 15231–15236. Note: This paper has been highlighted by media and journals such as Nature, Science Daily, and Science-Business eXchange(SciBX).
