个人简历
教授、博士生导师、海洋科学与生物工程学院院长、青岛科技大学十大杰出青年、青岛科技大学教育先锋、归国留学人员。主要围绕核酸检测中的信号识别和信号放大等关键问题，开展了核酸快速和高灵敏检测关键技术研究以及核酸等温检测新技术及其应用研究。在RNA一步法检测理论研究方面取得重大进展，并基于此构建了全新的 RNA 一步法等温扩增技术平台-SEA，并将这一系列成果分别发表在《美国化学会志》和《化学通讯》上，打破了原有DNA合成方法的认知。发明了多种等温均相核酸检测新方法，将核酸检测应用于食品安全与分子诊断领域，部分科研成果实现转化，开发出了一系列的荧光和比色的核酸检测试剂盒，并应用于食品中的致病微生物检测。2019年，新冠疫情爆发后，带领团队国内第一批推出核酸快速检测方案，成功研发新冠病毒核酸检测试剂盒并获得欧盟CE认证。主持国家自然科学基金面上项目2项，国家自然科学基金青年基金1项，首届山东省自然科学基金重大基础研究项目1项和山东省科技发展计划等多项课题。近年来，以第一作者或通讯作者在 “J. Am. Chem. Soc.”, “Clin. Chem.”, “Anal. Chem.”, “Chem. Commun.”和“Biosens. Bioelectron.”等国际高水平学术期刊上发表SCI论文40余篇。申请国家发明专利12项，授权5项。
研究领域
1. 核酸检测新技术的研究2. 纳米生物分析和生物传感新方法研究3. 生化检测新方法在食品安全和分子诊断等领域的应用""
近期论文
1. Chao Shi, Xiaotong Shen, Shuyan Niu, Cuiping Ma*.（第一或通讯作者）Innate reverse transcriptase activity of DNA polymerase for isothermal RNA direct detection[J].J. Am. Chem. Soc., 2015, 137: 13804-13806. (IF= 13.858)2. Xuejiao Wang, Shuyan Niu, Manman Wei, Shuai Liu, Rui Liu, Chao Shi, Cuiping Ma*.（第一或通讯作者）Ultrasensitive electrochemical DNA biosensor based on a tetrahedral structure and proximity-dependent surface hybridization[J].Analyst, 2020, 145: 150-156. (IF= 4.019)3. Shuai Liu, Manman Wei, Xuejiao Wang, Chao Shi, Shaoping Kuang*, Cuiping Ma*.（第一或通讯作者）An ultrasensitive electrochemical DNA sensing strategy free from pre-immobilization via G-quadruplex based homogenous proximity hybridization[J].Talanta, 2020, 120628. (IF= 4.916)4. Shuai Liu, Manman Wei, Rui Liu, Shaoping Kuang, Chao Shi, Cuiping Ma*.Lab in a Pasteur pipette: low-cost, rapid and visual detection of Bacillus cereu using denaturation bubble-mediated strand exchange amplification[J].Anal. Chim. Acta, 2019, 1080: 162-169. (IF= 5.265)5. Rui Liu, Xiudan Wang, Xuejiao Wang, Yanjing Shi, Chao Shi, Wei Wang, Cuiping Ma*.A simple isothermal nucleic acid amplification method for the effective on-site identification for adulteration of pork source in mutton[J].Food Control, 2019, 98: 297-302. (IF= 4.248)6. Cuiping Ma, Hao Jing, Pansong Zhang, Lingzhi Han, Meiling Zhang, Fuxin Wang, Shuyan Niu, Chao Shi. An ultrafast one-step assay for the visual detection of RNA virus[J].Chem. Commun., 2018, 54, 3118-3121. (IF= 6.319)7. Cuiping Ma, Fuxin Wang, Xiudan Wang, Lingzhi Han, Hao Jing, Heng Zhang and Chao Shi *.（第一或通讯作者）A novel method to control carryover contamination in isothermal nucleic acid amplification[J].Chem. Commun., 2017, 53, 10696-10699.(IF= 6.319)8. Chao Shi, Yifan Wang, Menghua Zhang, Cuiping Ma*.（第一或通讯作者）DNA Self-assembly Catalyzed by Artifcial Agents[J].Sci. Rep., 2017, 7(1):6818.(IF= 4.259)9. Chao Shi, Fanjin Shang, Mei Pan, Sen Liu, Cuiping Ma*. （第一或通讯作者）The isothermal amplification detection of double-stranded DNA based on a double-stranded fluorescence probe[J].Biosens. Bioelectron., 2016, 80: 54-58. (IF= 7.78)10. Chao Shi, Fanjin Shang, Meiling Zhou, Pansong Zhang, Yifan Wang, Cuiping Ma*. （第一或通讯作者）Triggered isothermal PCR by denaturation bubble-mediated strand exchange amplification[J].Chem. Commun., 2016, 52: 11551-11554. (IF= 6.319)11. Chao Shi, Qi Liu, Meiling Zhou, Haijie Zhao, Tao Yang, Cuiping Ma*.（第一或通讯作者）Nicking endonuclease-mediated isothermal exponential amplification for double-stranded DNA detection[J].Sensor. Actuat. B: Chem., 2016, 222: 221-225. (IF= 5.401)12. Cuiping Ma, Dianang Han, Meilian Deng, Jingfei Wang, Chao Shi*.（第一或通讯作者）Single primer-triggered isothermal amplification for double-stranded DNA detection[J].Chem. Commun., 2015, 51: 553-556. (IF=6.319)13. Cuiping Ma, Zhiwei Wu, Wenshuo Wang, Qianqian Jiang, Chao Shi*.（第一或通讯作者）Three-dimensional DNA nanostructures for colorimetric assay of nucleic acids[J]. J. Mater. Chem. B, 2015, 3: 2853-2857. (IF= 4.543)14. Cuiping Ma, Sen Liu, Chao Shi*.（第一或通讯作者）Ultrasensitive detection of microRNAs based on hairpin fluorescence probe assisted isothermal amplification[J].Biosens. Bioelectron., 2014, 58: 57-60. (IF=7.78)15. Cuiping Ma, Dianang Han, Chao Shi*.（第一或通讯作者）A new isothermal nucleic acids detection strategy mediated by double-nicked beacon[J].Chem. Commun., 2014, 50: 3799-3801. (IF=6.319)16. Chao Shi, Qi Liu, Cuiping Ma*, Wenwan Zhong*.（第一或通讯作者）Exponential strand-displacement amplification for detection of microRNAs[J].Anal. Chem., 2014, 86: 336-339. (IF=6.32)17. Cuiping Ma, Chunhui Zhao, Yujie Ge, Chao Shi*.（第一或通讯作者）Aptameric molecular switch for cascade signal amplification[J].Clin. Chem., 2012, 58: 384-390. (IF=8.008)18. Chao Shi, Yujie Ge, Hongxi Gu, Cuiping Ma*. （第一或通讯作者）Highly sensitive chemiluminescent point mutation detection by circular strand-displacement amplificationreaction [J].Biosens. Bioelectron., 2011, 26: 4697-4701. (IF=7.78)19. Cuiping Ma, Wenshuo Wang, Qing Yang, Chao Shi*, Lijie Cao.（第一或通讯作者）Cocaine detection via rolling circle amplification of short DNA strand separated by magnetic beads[J].Biosens. Bioelectron., 2011, 26: 3309-3312. (IF=7.78)20. Cuiping Ma, Lijie Cao, Chao Shi*, Naihao Ye*. （第一或通讯作者）The real-time PCR for sensitive protein detection by target-induced intermolecular hybridization[J].Chem. Commun., 2011, 47: 11303-11305. (IF=6.319)
