个人简历

陈罡，教授，博士生导师。中国科学院神经科学研究所博士，哈佛大学医学院、杜克大学医学中心博士后、杜克大学医学中心助理教授。现任江苏特聘教授，江苏特聘医学专家。入选教育部“新世纪优秀人才支持计划”、江苏省“333”工程中青年领军人才，江苏省“六大人才高峰”资助对象，江苏省“青蓝工程”优秀青年骨干教师，江苏省高校优秀共产党员，南通市青年岗位能手，南通大学“我最喜爱的老师”等，获江苏省科技进步二等奖。中国神经科学学会神经胶质细胞分会委员，江苏省神经科学学会理事，江苏省神经科学学会青年工作委员会副主任委员，《交通医学》杂志副主编，FrontiersinMolecularNeuroscience杂志编辑。
是江苏高校优秀科技创新团队(神经损伤与功能恢复)的带头人。主持国家重点研发计划子课题、国家自然科学基金面上项目、江苏省自然科学基金面上项目、江苏省高校自然科学重大项目等课题，在Cell,NatureNeuroscience,NatureCellBiology,Neuron,NatureCommunications,JCI,Brain等杂志上发表SCI论文31篇，影响因子合计超过258，被引1500余次。

研究领域

慢性疼痛和神经损伤后的功能恢复

近期论文

1.ChenG,ZhangYQ,QadriYJ,SerhanCN,JiRR.MicrogliainPain:Detrimentalandprotectiverolesinthepathogenesisandresolutionofpain.Neuron,2018,100(6):1292-1311.
2.SuWF,FanWu,JinZH,YunGu,ChenYT,FeiY,ChenH,WangYX,XingLY,ZhaoYY,YuanY,TangX,ChenG#.OverexpressionofP2X4receptorinSchwanncellspromotesmotorandsensoryfunctionalrecoveryandremyelinationviaBDNFsecretionafternerveinjury.Glia,2018;1–13.https://doi.org/10.1002/glia.23527.(通讯作者)
3.WeiZY,SuWF,LouHF,DuanSM,ChenG#.Traffickingpathwaybetweenplasmamembraneandmitochondriaviaclathrin-mediatedendocytosis.JournalofMolecularCellBiology,2018,1-10.doi:10.1093/jmcb/mjy060.(通讯作者)
4.GuY,WuYM,SuWF,XingLY,ShenYT,HeXW,LiLL,YuanY,TangX,ChenG#.17β-EstradiolenhancesSchwanncelldifferentiationviatheERβ-ERK1/2signalingpathwayandpromotesremyelinationininjuredsciaticnerves.Front.Pharmacol.2018.9:1026.Doi:10.3389/fphar.2018.01026.(通讯作者)
5.ChenG*,KimYH*,LiH,LuoH,LiuDL,ZhangZJ,LayM,ChangW,ZhangYQ,JiRR.PD-L1inhibitsacuteandchronicpain
bysuppressingnociceptiveneuronactivityviaPD-1.NatureNeuroscience.2017,Jul;20(7):917-926.
6.HuhY,JiRR,ChenG#.Neuroinflammation,bonemarrowstemcells,andchronicpain.Front.Immunol.8:1014.(2017).doi:10.3389/fimmu.2017.01014(通讯作者)
7.ChenG#,LuoX,QadriYJ,BertaT,JiRR.Sex-dependentglialsignalinginpathologicalpain:Distinctroleofspinalmicrogliaandastrocytes.NeuroscienceBulletin.2017.June5.Doi:10.1007/s12264-017-0145-y(通讯作者)
8.ChenG*,XieRG*,GaoYJ*,XuZZ*,ZhaoLX,BangSB,BertaT,ParkCK,LayM,ChenW,JiRR.β-arrestin-2regulatesNMDAreceptorfunctioninspinallaminaIIneuronsanddurationofpersistentpain.NatureCommunications.7,Articlenumber:12531(2016)doi:10.1038/ncomms12531.
9.ShenYT,GuY,SuWF,ZhongJF,JinZH,GuXS,ChenG#.Rab27bisinvolvedinlysosomalexocytosisandproteolipidproteintraffickinginoligodendrocytes.NeuroscienceBulletin.2016.August;32(4):331-340.(Coverstory)(通讯作者)
10.SuWF,GuY,WeiZY,ShenYT,JinZH,YuanY,GuXS,ChenG#.Rab27a/Slp2-acomplexisinvolvedinSchwanncellmyelination.NeuralRegenerationResearch.2016,11(11):1830-1838.(通讯作者)
11.ChenG#,ParkCK,XieRG,JiRR#.IntrathecalbonemarrowstromalcellsinhibitneuropathicpainviaTGF-bsecretion.TheJournalofClinicalInvestigation.2015;125(8):3226-3240.(共同通讯作者)
12.ChenG,ParkCK,XieRG,BertaT,NedergaardM,JiRR.Connexin-43induceschemokinereleasefromspinalcordastrocytestomaintainlate-phaseneuropathicpaininmice.Brain.2014Aug;137(Pt8):2193-2209.
13.ChenG#,ZhangZJ,WeiZY,ChengQ,LiX,LiW,DuanSM,GuXS#.LysosomalexocytosisinSchwanncellscontributestoaxonremyelination.Glia.2012,60(2):295-305.(共同通讯作者)
14.ChenG,LiHM,ChenYR,GuXS,DuanS.DecreasedestradiolreleasefromastrocytescontributestotheneurodegenerationinamousemodelofNiemann-PickdiseasetypeC.Glia.2007,55:1509-1518.
15.ZhangZ*,ChenG*,ZhouW*,SongA,XuT,LuoQ,WangW,GuXS,DuanS.RegulatedATPreleasefromastrocytesthroughlysosomeexocytosis.NatCellBiol.2007,9:945-953(共同第一作者)
16.LeeJH,ParkCK,ChenG,HanQ,XieRG,LiuT,JiRR*,LeeSY*.AmonoclonalantibodythattargetsaNaV1.7channelvoltagesensorforpainanditchrelief.Cell.2014;157(6):1393-404.
17.ParkCK,XuZZ,BertaT,HanQ,ChenG,LiuXJ,JiRR*.ExtracellularmicroRNAsactivatenociceptorneuronstoelicitpainviaTLR7andTRPA1.Neuron.2014Apr2;82(1):47-54.
18.SongAH,WangD,ChenG,LiYJ,LuoJH,DuanSM,PooMM.Aselectivefilterforcytoplasmictransportattheaxoninitialsegment．Cell，2009,136.1148-1160.