个人简历

基金项目：
国家自然科学基金，青年基金，81901098，抑制Ras法尼基化改善阿尔兹海默病认知功能的分子机制研究，2020–01至2022–12，20.50万，在研，主持。
江苏省自然科学基金，青年基金，BK20190923，抑制Ras 法尼基化抗痴呆的神经保护作用机制研究，2019–07至2022–6，20万，在研，主持。
南通市科学计划项目，JC2018009，小G 蛋白Ras 活性抑制对阿尔兹海默病认知功能的调控机制，2018–07至2020–06,5万，结题，主持

研究领域

神经药理""

近期论文

（1）Chen Tingting*; Cai Chengyun; Wang Lifeng; Li Shixin; Chen Ling *; Farnesyl Transferase Inhibitor Lonafarnib Enhances α7nAChR Expression Through Inhibiting DNA Methylation of CHRNA7 and Increases α7nAChR Membrane Trafficking, Frontiers in Pharmacology, 2020, 11.
（2）Chen Tingting#; Wang Ya#; Zhang Tingting; Zhang Baofeng; Chen Lei; Zhao Liandong; Chen Ling*; Simvastatin Enhances Activity and Trafficking of α7 Nicotinic Acetylcholine Receptor in Hippocampal Neurons Through PKC and CaMKII Signaling Pathways, Frontiers in Pharmacology, 2018, 9: 362.
（3）Chen Tingting; Tanaka Motoki; Wang Ya; Sha Sha; Furuya Kishio; Chen Ling*; Sokabe M*; Neurosteroid dehydroepiandrosterone enhances activity and trafficking of astrocytic GLT-1 via σ1 receptor-mediated PKC activation in the hippocampal dentate gyrus of rats, Glia, 2017, 65: 1491-1503.
（4）Chen Tingting; Wang Conghui; Sha Sha; Zhou Libin; Chen Lei*; Chen Ling*; Simvastatin Enhances Spatial Memory and Long-Term Potentiation in Hippocampal CA1 via Upregulation of α7Nicotinic Acetylcholine Receptor, Molecular Neurobiology, 2016, 53: 4060-4072.
（5）Chen Tingting; Zhang Baofeng; Li Guoxi; Chen Lei; Chen Ling*; Simvastatin enhances NMDA receptor GluN2B expression and phosphorylation of GluN2B and GluN2A through increased histone acetylation and Src signaling in hippocampal CA1 neurons, Neuropharmacology, 2016, 107: 411-421.