个人简历

Education\r
1998 BS, Nanjing University, China\r
2004 PhD, Columbia University, USA\r
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Academic career\r
2015-present Professor, State Key Laboratory of Elemento-organic Chemistry, Nankai University, China\r
2018-2021 Adjunct professor, The Pennsylvania State University, USA\r
2014-2015 Associate Professor, Department of Chemistry, The Pennsylvania State University, USA\r
2008-2014 Assistant Professor, Department of Chemistry, The Pennsylvania State University, USA\r
2005-2008 Postdoctoral fellow, Memorial Sloan-Kettering Cancer Center, USA\r
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Honors \r
ACP lectureship awards in Japan and Malaysia, 2018 \r
National Natural Science Fund for Distinguished Young Scholars of China, 2017 \r
WuXi AppTec Scholar Award in Life Science and Chemistry, 2016 \r
Distinguished Junior Faculty Award by Chinese-American Chemistry & Chemical Biology \r
Professor Association (CAPA), 2014 \r
Amgen Young Investigator Award, 2013 \r
Thieme Chemistry Journal Award, 2011 \r
National Science Foundation (NSF) CAREER Award, 2011

研究领域

"""""Metal catalysis: \r
Development of metal-catalyzed C-H functionalization reactions (e.g. Pd

近期论文

Bioconjugation via Hetero-selective Clamping of Two Amines with ortho-Phthalaldehyde. Xin Chu, Bo Li, Hao-Yang Liu, Xiaowei Sun, Xiaochen Yang, Gang He, Chuanzheng Zhou, Weimin Xuan, Shu-Lin Liu*, and Gong Chen*, Angew. Chem., Int. Ed. 2023, xx, accepted. DOI: 10.1002/anie.202212199\r
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Synthesis of N-acyl sulfenamides via copper catalysis and their use as S-sulfenylating reagents of thiols. Ziqian Bai, Shiyang Zhu, Yiyao Hu, Peng Yang, Xin Chu, Gang He, Hao Wang*, and Gong Chen*. Nat. Commun. 2022, 13, 6445. DOI: 10.1039/d2qo01114j\r
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Preface – Special topic in asymmetric C-H functionalization (editorial as guest editor). Gong Chen*, and Shigeki Matsunaga*, Synthesis 2022, 54, 4690-4690. DOI: 10.1055/s-0040-1720049\r
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Hypervalent-iodine promoted selective cleavage of C(sp3)–C(sp3) bonds in ethers. Yaxin Wang*, Qin He, Cehui Cao, Peng Wang, Gong Chen*, and Matthias Beller*, Org. Chem. Front 2022, 9, 5592-5598. DOI: 10.1039/d2qo01114j\r
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Palladium-Catalyzed Methionine-Facilitated β and γ C(sp3)–H Arylation of N-Terminal Aliphatic Amino Acids of Peptides Xiangxiang Chen, Bo Li, Huarong Tong, Liping Qi, Gang He, Gong Chen. Chin. J. Chem. 2022, 40, 2502-2506.\r
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Introduction to ‘Synthesis and chemical biology of macrocycles’ (editorial as guest editor). Gong Chen, Monika Raj, and Andrei Yudin. RSC Chem. Biol. 2022, 3, 993-993. DOI: 10.1039/d2cb90018a\r
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Ruthenium-Catalyzed Pyridine-Directed Aryl C–H Glycosylation with Glycosyl Chlorides. Shaokun Cai, Qikai Sun, Quanquan Wang, Gang He* and Gong Chen*. J. Org. Chem. 2022, 87, 8811–8818.\r
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Construction of Complex Macromulticyclic Peptides via Stitching with Formaldehyde and Guanidine. Bo Li+, Zhao Wan+, Hanliang Zheng, Shaokun Cai, Hanwen Tian, Hong Tang, Xin Chu, Gang He, Dong-Sheng Guo, Xiao-Song Xue*, and Gong Chen*. (+co-first author) J. Am. Chem. Soc. 2022, 144, 10080–10090.\r
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Iron-Catalysed Reductive Cross-Coupling of Glycosyl Radicals for the Stereoselective Synthesis of C-glycosides. Quanquan Wang+, Qikai Sun+, Yi Jiang, Huixing Zhang, Lu Yu, Changlin Tian, Gong Chen*, & Ming Joo Koh* Nat. Synth. 2022, 1, 235–244. (+co-first author)\r
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Extendable Stapling of Unprotected Peptides via Crosslinking Two Amines with o-Phthalaldehyde. Bo Li, Lan Wang, Xiangxiang Chen, Xin Chu, Hong Tang, Jie Zhang, Gang He, Li Li*, and Gong Chen* Nat. Commun. 2022, 13, 311.\r
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Synthesis of 2-Deoxy-C-Glycosides via Iridium-Catalyzed sp2 and sp3 C–H Glycosylation with Unfunctionalized Glycals. Wanjun Zhu, Qikai Sun, Huixing Zhang, Hai Chang, Hui-Xing Zhang, Quanquan Wang, Gong Chen*, and Gang He*. Chin. J. Chem. 2022, 40, 571-576.\r
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Arene C–H Iodination Using 2-Nitrophenyl Iodides as the Iodinating Reagents (highlight) Huarong Tong and Gong Chen*. Chin. J. Org. Chem. 2021, 41, 4103-4104. DOI: 10.6023/cjoc202100077\r
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Construction of Peptide Macrocycles via Palladium-Catalyzed Multiple S-Arylation: An Effective Strategy to Expand the Structural Diversity of Crosslinkers. Xin Chu, Linhua Shen, Bo Li, Peng Yang, Chengzhuo Du, Xiaoye Wang, Gang He, Samir Messaoudi*, and Gong Chen*. Org. Lett. 2021, 23, 8001–8006.\r
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Solid Phase Synthesis of Thioether-linked Peptide Macrocycles via Palladium-Catalyzed Intramolecular S-Arylation and S-Alkenylation. Peng Yang, Chao Zhang, Bo Li, Gang He, and Gong Chen*. Asian J. Org. Chem. 2021, 10, 2888-2891.\r
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Tunable System for Electrochemical Reduction of Ketones and Phthalimides. Yaxin Wang*, Jianyou Zhao, Qiuping Zhao, Jian Zhang, and Gong Chen. Chin. J. Chem. 2021, 39, 3297-3302.\r
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Nitrene-mediated P–N Coupling Under Iron Catalysis Ziqian Bai, Fangfang Song, Hao Wang,* Wangxing Cheng (本科生), Shiyang Zhu, Yi Huang, Gang He, and Gong Chen* CCS Chem. 2021, 3, 2538-2546. DOI: 10.31635/ccschem.021.202101056.\r
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Stereoselective Synthesis of C-Vinyl Glycosides via Palladium-Catalyzed C–H Glycosylation of Alkenes Qikai Sun, Huixing Zhang, Quanquan Wang, Tianjiao Qiao, Gang He,* and Gong Chen* Angew. Chem., Int. Ed. 2021, 60, 19620-19625. DOI: 10.1002/anie.202104430 and 10.1002/ange.202104430\r
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Iridium-catalyzed intermolecular N—N coupling for hydrazide synthesis using N-benzoyloxycarbamates as acyl nitrene precursor Fangfang Song, Shiyang Zhu, Hao Wang,* and Gong Chen* Chin. J. Org. Chem. 2021, 41(10), 4050-4058. DOI: 10.6023/cjoc202105045.\r
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Photoredox-Mediated Mono- and Difluorination of Remote Unactivated Methylene C(sp3)–H Bonds of N-Alkyl Sulfonamides Zhiqiang Deng, Zhenxiang Zhao, Gang He, Gong Chen* Org. Lett. 2021, 23, 3631-3635. DOI: 10.1021/acs.orglett.1c01020.\r
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β-Lactam Synthesis via Copper-Catalyzed Directed Aminoalkylation of Unactivated Alkenes with Cyclobutanone O-Benzoyloximes Heng Zhang, Xiaoyan Lv, Hanrui Yu (本科生), Zibo Bai, Gong Chen*, and Gang He* Org. Lett. 2021,23, 3620-3625. DOI: 10.1021/acs.orglett.1c01007.