个人简历
教育经历 2003-2008 南开大学生命科学学院，微生物专业，博士 1999-2003 吉林大学生命科学学院，生物制药专业，学士 工作经历 2017-至今 南开大学生命科学学院，副教授 2015-2017 南开大学药学院，副教授 2013-2015 美国佛罗里达大学医学院，博士后 2008-2012 南开大学药学院，讲师
研究领域
细菌感染性疾病 致病机制和耐药机制 抗菌药物靶标的发现与抗菌机制研究 抗MRSA卤代吩嗪化合物 铜绿假单胞菌的III型分泌系统（T3SS） T3SS的激活机制 T3SS作为蛋白质转染工具的应用
近期论文
F Bai, Z Li, A Umezawa, N Terada, S Jin*. Bacterial type III secretion system as a protein delivery tool for a broad range of biomedical applications. Biotechnology Advances, 2018, 36: 482-493. Y Jin, Y Liu, Z Li, K Santostefano, J Shi, X Zhang, D Wu, Z Cheng, W Wu, N Terada, S Jin*, F Bai*. Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery. 2018, PLoS ONE 13(3): e0194895. F Bai, CH Lim, J Jia, KE Santostefano, C Simmons, H Kasahara, N Terada, S Jin. Directed differentiation of embryonic stem cells into cardiomyocytes by bacterial injection of defined transcription factors. Scientific Reports, 2015, 5, 15014. AT Garrison, F Bai (co-first), Y Abouelhassan, NG Paciaroni, S Jin, RW Huigens III*. Bromophenazine derivatives with potent inhibition, dispersion and eradication activities against Staphylococcus aureus biofilms. RSC Advances, 2015, 5 (2), 1120-1124. J Jia, F Bai (co-first), Y Jin, KE Santostefano, UH Ha, D Wu, W Wu*, N Terada*, S Jin*. Efficient gene editing in pluripotent stem cells by bacterial injection of transcription activator-like effector nuclease proteins. Stem cells translational medicine, 2015, 4(8): 913-926. X Cao, C Zhang, Y Dong, P Geng, F Bai*, G Bai. Modeling of cooked starch digestion process using recombinant human pancreatic alpha-amylase and maltase-glucoamylase for in vitro evaluation of alpha-glucosidase inhibitors. Carbohydrate Research, 2015, 414, 15-21. Y Liu, L Ren, L Ge, Q Cui, X Cao, Y Hou, F Bai*, G Bai. A strategy for fusion expression and preparation of functional glucagon-like peptide-1 (GLP-1) analogue by introducing an enterokinase cleavage site. Biotechnology letters, 2014, 36 (8), 1675-1680. L Wang, Y Hou, J Peng, X Qi, F Bai*, G Bai. Bioactivity-based HPLC tandem Q/TOF for alpha-glucosidase inhibitors. Screening, identification, and quantification from Actinomycetes. Latin American Journal of Pharmacy, 2012, 31 (5): 693-698. F Bai, H Xu, Q Zhang, X Qi, R Mou, G Bai, M Qiao. Functional characterization of pfm in protein secretion and lung infection of Pseudomonas aeruginosa. Canadian Journal of Microbiology, 2011, 57: 829-837. P Meng, Y Guo, Q Zhang, J Hou, F Bai*, P Geng, G Bai. A novel amino-oligosaccharide isolated from the culture of Streptomyces strain PW638 is a potent inhibitor of α-amylase. Carbohydrate Research, 2011, 346: 1898-1902. L Ren, X Cao, P Geng, F Bai*, G Bai. Study of the inhibition of two human maltase-glucoamylases catalytic domains by different α-glucosidase inhibitors. Carbohydrate Research, 2011, 346: 2688-2692.
