个人简历

2005年～2009年 就读于北京师范大学，获学士学位\r
2009年～2014年就读于中国科学院大学，获博士学位\r
2015年～2018年 美国伦斯勒理工学院，博士后\r
2018年～2019年 美国奥尔巴尼分子制药公司，研究科学家\r
2019年～至今 南京师范大学食品与制药工程学院，教师。主要从事糖化学生物学、酶催化、有机合成和药物合\r
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获奖及荣誉\r
2020年入选 “江苏省教授”\r
2020年入选“江苏省双创博士”\r
2019年入选南京师范大学“中青年领军人才”\r
2019年入选南京师范大学“鱼跃学者”\r
2019年获南京师范大学“十项主要科研进展”\r
2020年当选江苏省青年科学家年会执行委员会委员

研究领域

"""""近五年围绕糖胺聚糖药物的设计、合成、结构解析和生物活性方面展开了系列深入研究，取得了较突出的成果与创新。将有机合成的理念、方法与生物催化相结合，发展了高效可控的化学酶法策略，实现了对复杂糖胺聚糖合成过程的精准调控。"

近期论文

X. Zhang, L. Lin, H. Huang*, R. J. Linhardt*, Chemoenzymatic Synthesis of Glycosaminoglycans. Accounts of Chemical Research, 2020, 53, 335-346.（封面文章）\r
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X. Zhang, X. Han, K. Xia, Y. Xu, Y. Yang, K. Oshima, S. M. Haeger, M. J. Perez, S. A. McMurtry, J. A. Hippensteel, J. A. Ford, P. S. Herson, J. Liu, E. P. Schmidt, R. J. Linhardt*, Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions. PNAS, 2019, 116, 9208-9213.\r
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T. Suo, M. Sohail, Y. Ma, B. Li*, Y. Chen*, X. Zhang*, X. Zhou*, A versatile turn-on fluorometric biosensing profile based on split aptamers-involved assembly of nanocluster beacon sandwich. Sensors and Actuators B: Chemical, 2020, in press.\r
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T. Suo, M. Sohail, S. Xie, B. Li*, Y. Chen*, L. Zhang*, X. Zhang*, DNA nanotechnology: A recent advancement in the monitoring of Microcystin-LR. Journal of Hazardous Materials, 2020, in press.\r
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X. Zhang, V. Pagadala, H. M. Jester, A. M. Lim, T. Q. Pham, A. M. P. Goulas, J. Liu*, R. J. Linhardt*. Chemoenzymatic synthesis of heparan sulfate and heparin oligosaccharides and NMR analysis: Paving the way to a diverse library for glycobiologists. Chemical Science, 2017, 8, 7932-7940. （内封面文章）\r
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L. Lin, M. Qiao, X. Zhang*, R. J. Linhardt*. Site-selective reactions for the synthesis of glycoconjugates in polysaccharide vaccine development. Carbohydrate Polymers, 2020, 230, 115643.\r
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Y. Ji, S. Zhang, M. Qiao, R. Jiao, J. Li, P. Song, X. Zhang*, H. Huang*. Synthesis of structurally defined chondroitin sulfate: Paving the way to the structure-activity relationship studies. Carbohydrate Polymers, 2020, 248, 116796.\r
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J. Li, M. Qiao, Y. Ji, L. Lin, X. Zhang*, R. J. Linhardt*. Chemical, enzymatic and biological synthesis of hyaluronic acids. International Journal of Biological Macromolecules, 2020, 152, 199-206.\r
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M. Qiao, L. Lin, K. Xia, J. Li, X. Zhang*, R. J. Linhardt*. Recent advances in biotechnology for heparin and heparan sulfate analysis. Talanta, 2020, 219, 121270. \r
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L. Lin, Y. Yu, F. Zhang, K. Xia, X. Zhang*, R. J. Linhardt*, Bottom-up and top-down profiling of pentosan polysulfate. Analyst, 2019, 144 , 4781-4786.