鲍恩东
近期热点
资料介绍
个人简历
鲍恩东,1963 年 12 月生,国际动物卫生学会(International society of Animal Hygiene,ISAH)常务理事,中国兽医病理学分会常务理事,民进江苏省委科技工作委员会委员。1979 年-1983年本科就读于宁夏农学院畜牧兽医系,1983 年毕业后留该校任助教。1985-1988年于内蒙古农牧学院攻读动物病理学硕士学位,毕业后返宁夏农学院牧医系任助教、讲师。1992 年考入南京农业大学攻读兽医病理学博士学位,1995 年毕业后留南京农业大学动物医学院病理教研组任讲师、副教授、教授。1999 年-2000年、2001-2002 年及 2004-2005 年曾多次留学于德国康斯坦茨大学生物系和汉诺威兽医大学。曾进行过猪喘气病、畜禽肿瘤调查、兔病毒性出血症、鸡传染性法氏囊病、鸡马立克氏病胚胎免疫、畜禽应激蛋白和应激损伤发生机制等研究。主编《动物病理学》和副主编《动物产品卫生检验》;参加《兽医病理学》、《动物病理学》、《家畜病理生理学》、《家畜病理解剖学》等专著和教材的编写任务。科研项目主要涉及热休克蛋白和应激损伤、新型兽药研发等。在国内外核心期刊发表研究论文 180 余篇,其中在国外重要的 SCI 源期刊中发表学术论文 50 余篇。主持制订农业部《饲料中妥曲珠利的测定 高压液相色谱法》部颁标准。科研项目:1.主持国家自然科学基金项目“运输应激猪热休克蛋白表达规律及应对应激损伤的分子机制”(30972165),2010-2012。2. 主持农业部公益性行业(农业)科研专项项目“家畜生产运输过程中环境应激响应及调控技术研究”之子项目(201003060-11),2010-2014。3. 主持教育部博士点基金项目(博导类)“BCG-PSN 干预免疫细胞信号转导和细胞凋亡的作用机制”(20100097110007),2011-2013。 4. 主持 “磷酸替米考星原料药、可溶性粉三类新兽药临床前及临床试验研究”项目(横向),2011-2012。5.主持中德农业科技合作项目“集约化动物生产环境及其周边空气中空气源性微生物(包括人兽共患病病原)及微细粉尘检测与预防”(42/04-05CHN20)和“环境应激对猪器官组织及鼠细胞模型热休克蛋白表达的相关性研究”(29/08-09CHN21),2012-2013。6.主持 “糜蛋白酶原料、胰蛋白酶原料及复合蛋白酶乳房注入剂新兽药应用与开发研究” 项目(横向),2012-2013。7.主持国家重点基础研究发展规划(973 计划)项目子项目“猪繁殖力的生理学及相关遗传调控机理”(2014CB138502),2014-2018。8.主持国家自然科学基金项目“热休克蛋白过表达抵抗心肌应激损伤的分子机制”(31372403),2014-2017。9. 主持国家自然科学基金项目“热休克蛋白表达和翻译后修饰在鸡心肌细胞抗热应激损伤中的保护作用”(31672520),2017-2020。荣誉奖项:主持项目《应激性心肌损伤及诱导表达热休克蛋白抗应激损伤的分子机制》分获教育部自然科学奖二等奖和研究江苏省教育科学研究成果奖(高校科学技术研究类)自然科学奖二等奖(2016)。发明专利:1.一种治疗畜禽疾病的多聚核苷酸微囊及其制备方法;南京农业大学,南京农大新兽药开发工程技术有限公司;发明专利;鲍恩东,吕英军,苏建东;授权号:ZL200910028167.8;授予时间:2011.1.262.支链淀粉衍生物修饰口服兽用卡介菌多糖核酸(BCG-PSN)脂质体及其冻干制剂;南京农业大学,南京农大新兽药开发工程技术有限公司;发明专利;鲍恩东,王晓斌;授权号:ZL201010242300.2;授予时间:2011.11.23研究领域
免疫病理及分子病理""近期论文
1. Miao Zhang, Zhenhua Yue, Zhijun Liu, Ali Islam, Buriro Rehana, Shu Tang,Endong Bao, Jörg Hartung,Hsp70 and HSF-1 expression is altered in the tissues ofpigs transported for various periods of times,Journal of Veterinary Science,2012,13(3), 253-259.2.唐姝,陈娟,高建龙, 鲍恩东,饲料中磺胺氯吡嗪钠含量的高效液相色谱(HPLC)检测方法的建立,南京农业大学学报,2012,35(2):105-109.3. Jochen Schulz, Endong Bao, Marcus Clauβ, Jörg Hartung, The potential of a newair cleaner to reduce airborne microorganisms in pig house air: preliminary results,Berliner und Münchener Tierärztliche Wochenschrift,2013,126 (3/4): 143-148.4. 张晓辉,张春兰,宗昕如,辛凌翔,杨迪,刘彩,沈向荣,鲍恩东,褚德明,王文超,磷酸替米考星对人工感染猪肺炎支原体病的治疗试验,中国兽医科学,2013,43(05):515-521.5. Shu Tang,Rehana Buriro, Zhijun Liu, Miao Zhang, Islam Ali, Abdelnasir Adam,Jörg Hartung, Endong Bao*,Localization and Expression of Hsp27 and aB-Crystallinin Rat Primary Myocardial Cells during Heat Stress In Vitro,PLoS ONE,2013,8(7):e69066. doi:10.1371/journal.pone.0069066.6. 刘彩,沈向荣,杨迪,张晓辉,宗昕如,王文超,鲍恩东,磷酸替米考星在猪组织中的残留消除研究,中国农业大学学报,2013,18(4):134-140.7. 杨迪,张春兰,刘彩,沈向荣,张晓辉,宗欣茹,王文超,鲍恩东,磷酸替米考星在肉鸡组织内消除规律研究,南京农业大学学报,2013,36(4):111-115.8. 宗昕如,张晓辉,辛凌翔,杨迪,刘彩,沈向荣,鲍恩东,褚德明,王文超,磷酸替米考星可溶性粉对人工感染鸡支原体病的治疗试验,畜牧与兽医,2013,45(8):88-92.9. 沈向荣,苏亚楠,刘彩,杨迪,张晓辉,宗欣茹,王文超,张淼,张翔,鲍恩东,磷酸替米考星在猪体内的药代动力学研究,南京农业大学学报,2013,36(5):120-12410.Shu Tang, Jimian Yu, Miao Zhang, Endong Bao*. Effects of different heat stressperiods on various blood and meat quality parameters in young Arbor Acer broilerchickens,Canadian Journal of Animal Science,2013,93(4):453-460.11. Shu Tang,Yinjun Lv#, Hongbo Chen, Abdelnasir Adam, Yanfen Cheng, JörgHartung, Endong Bao* , Comparative analysis of αB-Crystallin expression inheat-stressed myocardial cells in vivo and in vitro,PLOS ONE,2014,9(1):e86937.doi:10.1371/journal.pone.008693712. Joyce Wanjiru Maingi,熊祺琰,韦艳娜,马庆红,纪燕,William Kimaru,华利忠,王佳,邵国青,鲍恩东,套式 PCR 检测中国江苏省猪场猪鼻支原体和猪肺炎支原体的感染情况,中国人兽共患病杂志,2014,30(8):800-805. 13. Hongbo Chen, Abdelnasir Adam, Yanfen Cheng, Shu Tang, J. Hartung, EndongBao*, Localization and expression of heat shock protein 70 with rat myocardial celldamage induced by heat stress in vitro and in vivo, Molecular Medicine Reports,2015,11: 2276-228414. 吴垒,曹曰莹,宗欣如,白庚辛,史宁花,杨树鑫,鲍恩东,牛奶和血清中胰蛋白酶活性的体外检测试验,畜牧与兽医,2015,47(2):30-34.15. Di Wu, Jiao Xu, Erbao Song, Shu Tang, Xiaohui Zhang, N. Kemper, J. Hartungand Endong Bao*, Acetyl salicylic acid protected against heat-stress damage inchicken myocardial cells and may associate with induced Hsp27 expression,CellStress and Chaperone,2015,20(4):687-696.16. 王喆,刘茜倩,庞博,张晓辉,鲍恩东,糜蛋白酶和胰蛋白酶体外微生物敏感性研究,南京农业大学学报,2015,38(4):636-644.17. Shu Tang,Jörg Hartung, Endong Bao*,The expression profiles of Hsp27 andαB-crystallin and their relationship in heat-stressed rat myocardial cells in vitro and invivo,Molecular Medicine Reports,2016,13: 1633-1638.18. Shu Tang,Hongbo Chen, Yanfen Cheng, Mohammad Abdel Nasir, NicoleKemper,Endong Bao*,The interactive relationship between heat shock factor 1 andheat shock proteins in primary myocardial cells subjected to heat stress,InternationalJournal of Molecular Medicine,2016,37(1): 56-62.19. Xiaohui Zhang, Huaisen Zhu, Zhuang Qian, Shu Tang,Di Wu, Nicole Kemper,Jörg Hartung, Endong Bao *. The association of Hsp90 expression induced by aspirinwith anti-stress damage in chicken myocardial cells, The Journal of VeterinaryScience, 2016, 17(1):35-44.20. Di Wu, Miao Zhang,Jiao Xu,Erbao Song,Yingjun Lv, Shu Tang,Xiaohui Zhang,N. Kemper,Jörg Hartung, Endong Bao*,In vitro evaluation of aspirin-inducedHspB1 against heat stress damage in chicken myocardial cells,Cell Stress andChaperone,2016,21(3):405-413. (DOI:10.1007/s12192-016-0666-8)21. Xiaohui Zhang, Zhe Wang, Bing Yin,Hong Wu,Shu Tang,Lei Wu,Yanan Su,Ye Lin,Xiqian Liu,Bo Pang,Nicole. Kemper,Jörg Hartung, Endong Bao *,Acomplex of trypsin and chymotrypsin effectively inhibited growth of pathogenicbacteria inducing cow mastitis and showed synergistic antibacterial activity with antibiotics,Livestock Science,2016,188:25-36. (DOI:10.1016/j.livsci.2016.03.017).22. Ruicheng Wei, Feng Ge, Lili Zhang, Xiang Hou, Yinan Cao, Lan Gong, MingChen, Ran Wang, Endong Bao. Occurrence of 13 veterinary drugs in animalmanure-amended soils in Eastern China, Chemosphere, 2016, 144: 2377-2383.23. Xiaohui Zhang, Zhuang Qian, Huaisen Zhu, Shu Tang,Di Wu,Nicole. Kemper,Jörg Hartung, Endong Bao*,HSP90 gene expression induced by aspirin is associatedwith damage remission in a chicken myocardial cell culture exposed to heat stress,British Poultry Science, 2016,57(4): 462 - 473.24. Di Wu, Miao Zhang,Yingjun Lv, Shu Tang,Nicole. Kemper,Jörg Hartung,Endong Bao*,Aspirin-induced heat stress resistance in chicken myocardial cells canbe suppressed by BAPTA-AM in vitro,Cell Stress and Chaperone,2016,21(5),817-827 (DOI:10.1007/s12192-016-0706-4)25. Yanfen Cheng, Jiarui Sun, Hongbo Chen, Abdelnasir Adam, Shu Tang, NicoleKemper,Jörg Hartung and Endong Bao*,Expression and location of HSP60 andHSP10 in the heart tissue of heat-stressed rats,Experimental and TherapeuticMedicine,2016,12: 2759-2765.26. Erbao Song,Shu Tang,Jiao Xu,Bin Yin,Endong Bao,Jörg Hartung,Lenti-siRNA Hsp60 promote bax in mitochondria and induces apoptosis during heatstress,Biochemical and Biophysical Research Communications,2016,481:125-131. 相关热点
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