芮蒙杰
近期热点
资料介绍
个人简历
近年来从事新型的多功能生物材料研究,结合多学科交叉研究的优势,通过结构设计和可控修饰得到模拟生物活性的大分子材料,在靶向药物输送、肿瘤治疗和多模态生物影像等多个领域进行综合应用,并证明了这些大分子材料在提高肿瘤治疗的特异性和有效性、实现精准治疗等方面具有独特的优势。在国际学术期刊上发表多篇学术论文,其中包括MolecularPharmaceutics,Internationaljournalofpharmaceutics等药剂领域专业期刊。研究成功先后获得国家自然科学青年基金、江苏省自然科学青年基金以及面上项目等项目资助。受教育及研究工作经历2017.05-至今,江苏大学,药学院,药剂学系,副教授2013.03-2017.04,江苏大学,药学院,药剂学系,讲师2008.09-2012.12,上海交通大学,生命科学技术学院,生物医学工程,博士,导师:徐宇虹教授2004.09-2008.06,上海交通大学,生命科学技术学院,生物工程,学士主要科研项目:1、江苏省自然科学基金面上项目(BK20181445),201807-202106,主持。2、国家自然科学基金青年科学基金项目(81402880),201501-201712,主持。3、江苏省自然科学基金青年项目(BK20130541),201307-201607,主持。4、江苏大学高级人才科研启动基金(14JDG163),201407-202006,主持。5、国家自然科学基金青年科学基金项目(81102395),201201-201412,参加。招生方向:热忱欢迎有志从事科研工作的本科生、研究生到我们课题组学习工作。欢迎具有药学、生物医学、化学以及材料背景的同学报考。有疑问可邮件联系。讲授课程:制剂工程学工业药剂学PreparationEquipmentandProcessDesignWorkshop(海外教育学院)IndustrialPharmaceutics(海外教育学院)PharmaceuticalMolecularBiology(海外教育学院)研究领域
主要研究方向及兴趣包括:1.新型仿生纳米材料的开发及其在药物输送、治疗研究和生物成像上的应用2.多功能敏感型纳米材料在生物成像、肿瘤治疗与联合治疗上的应用近期论文
1.ChunlaiFeng,HaishengZhang,JiamingChen,SiqiWang,YuanrongXin,YangQu,QiZhang,WeiJi,FumiyoshiYamashita,andMengjieRui*.RatiometricCo-EncapsulationandCo-DeliveryofDoxorubicinandPaclitaxelbyTumor-TargetedLipodisksforCombinationTherapyofBreastCancer.Internationaljournalofpharmaceutics,560(2019):191-204.2.ChunlaiFeng,XianqinYuan,KexinChu,HaishengZhang,WeiJi,andMengjieRui*.PreparationandOptimizationofPoly(LacticAcid)NanoparticlesLoadedwithFisetintoImproveAnti-CancerTherapy.Internationaljournalofbiologicalmacromolecules,125(2019):700-10.3.HailingTang,MengjieRui,ChuangYu,TaoChu,ChaoLi,ZhenzhenZhan,HaoCao,HangwenLi,ZhongminLiu,andHaifaShen.NanotechnologyinGenerationandBiomedicalApplicationofInducedPluripotentStemCells.NanoLife,8,no.04(2018):1841002.4.QiZhang,JianZhang,SongXue,MengjieRui,BinGao,AngLi,JiashuaiBai,ZhichaoYin,andEbubedikeMitchelleAnochie.EnhancedEnantioselectivityofNativeΑ‐CyclodextrinsbytheSynergyofChiralIonicLiquidsinCapillaryElectrophoresis.Journalofseparationscience,41,no.24(2018):4525-32.5.ChunlaiFeng#,MengjieRui#,HaijunShen,YuanrongXin,JieZhang,JunLi,LixiangYue,WenlongLai,XimingXu*.Tumor-specificdeliveryofdoxorubicinthroughconjugationofpH-responsivepeptideforovercomingdrugresistanceincancer,InternationalJournalofPharmaceutics,2017,528(1-2):322-333.6.MengjieRui#,YuanrongXin,RanLi,YanruGe,ChunlaiFeng*,andXimingXu*.TargetedBiomimeticNanoparticlesforSynergisticCombinationChemotherapyofPaclitaxelandDoxorubicin,MolecularPharmaceutics,2017,14(1):107-123.7.MengjieRui#,YangQu,TongGao,YanruGe,ChunlaiFeng*,andXimingXu*.Simultaneousdeliveryofanti-miR21withdoxorubicinprodrugbymimeticlipoproteinnanoparticlesforsynergisticeffectagainstdrugresistanceincancercells,InternationalJournalofNanomedicine,2017,12:217-237.8.MengjieRui#,HailingTang,YanLi,XiaohuiWei,andYuhongXu*.RecombinantHighDensityLipoproteinNanoparticlesforTarget-SpecificDeliveryofsiRNA.Pharmaceuticalresearch,2013,30(5):1203-14.9.MengjieRui#,WeiGuo,QianDing,XiaohuiWei,JianrongXu,andYuhongXu*.Recombinanthigh-densitylipoproteinnanoparticlescontaininggadolinium-labeledcholesterolformorphologicandfunctionalmagneticresonanceimagingoftheliver.Internationaljournalofnanomedicine,2012,7:3751-3768.10.HailingTang,XiaojingChen,MengjieRui,WenqiangSun,JianChen,JinliangPeng,andYuhongXu*.EffectsofsurfacedisplayedtargetingligandGE11onliposomedistributionandextravasationintumor.MolecularPharmaceutics,2014,11(10):3242–3250.11.YanLi,MengjieRui,HailingTang,andYuhongXu*.ThedistributionandcelluptakeofApoA1modifiedlipidcarriersofsiRNAinmouseliverinvivo.AsianJournalofPharmaceuticalSciences,2013,8:228-233.12.JunhuaMai,ShuxianSong,MengjieRui,DanLiu,QianDing,JinliangPeng,YuhongXu*.AsyntheticpeptidemediatedactivetargetingofcisplatinliposomestoTie2expressingcells.JournalofControlledRelease,2009,139(3):174–181.2009.13.XiaomengZhang*,HuanjunYang*,KeGu,JianChen,MengjieRui,andGuo-LiangJiang.Invitroandinvivostudyofananoliposomalcisplatinasaradiosensitizer.Internationaljournalofnanomedicine,2011,6:437-444. 相关热点
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