Insights into quinaldic acid moiety formation in thiostrepton biosynthesis facilitating fluorinated thiopeptide generation.Lian Duan#; Shoufeng Wang#; Ri Jing Liao; Wen Liu*.Chem.Biol., 2012, 19, 443-448（IF: 6.64）.Opportunities and challenges from current investigations into the biosynthetic logic of nosiheptide-represented thiopeptide antibiotics.Shoufeng Wang; Shuai-xiang Zhou; Wen Liu*.Curr. Opin. Chem. Biol., 2013, 17, 626-634（IF：9.85）.Discovery and efficient synthesis of a biologically active alkaloid inspired by thiostrepton biosynthesis.Qing-Fei Zheng; Shoufeng Wang*; Wen Liu*.Tetrahedron, 2014, 70, 7686-7690（IF：2.64）.Target-oriented design and biosynthesis of thiostrepton-derived thiopeptide antibiotics with improved pharmaceutical properties.Shoufeng Wang#；Qingfei Zheng#；Jianfeng Wang； Zhixiong Zhao；Qingye Li；Yunsong Yu; Renxiao Wang; Wen Liu*.Org. Chem. Front., 2015, 2, 106–109（IF：4.69）.Thiopeptide antibiotics exhibit a dual mode of action against intracellular pathogens by affecting both host and microbe.Qingfei Zheng#; Qinglan Wang#; Shoufeng Wang#; Jiequn Wu; Qian Gao*; Wen Liu*.Chem. Biol., 2015, 22, 1002-1007（IF: 6.64）.Concurrent modifications of the C-terminus and side ring of thiostrepton and their synergistic effects with respect to improving antibacterial activities.Shoufeng Wang#*; Qingfei Zheng#; Jianfeng Wang; Dandan Chen; Yunsong Yu; Wen Liu*.Org. Chem. Front., 2016, 3, 496-500（IF：4.69）.Precursor-directed mutational biosynthesis facilitates the functional assignment of two cytochromes P450 in thiostrepton biosynthesis.Qingfei Zheng#; Shoufeng Wang#*; Rijing Liao; Wen Liu*.ACS Chem. Biol., 2016, 11, 2673−2678（IF：5.09）. An α/β-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization.Qingfei Zheng#, Shoufeng Wang#, Panpan Duan, Rijing Liao, Dandan Chen, Wen Liu*.Proc. Natl. Acad. Sci. USA., 2016, 113, 14318-14323（IF：10.28）.
