个人简历

师玲玲，医学博士，暨南大学粤港澳中枢神经再生研究院副研究员，硕士生导师。2010年博士毕业于暨南大学，内科学专业。2011年至2013年于美国南加州大学Zilkha神经遗传研究所从事博士后工作。上述研究获得国家自然科学基金青年项目、面上项目，国家重点研发计划，教育部留学回国人员科研启动项目，广东省普通高校特色创新项目，暨南大学科研培育与创新基金研究项目等基金资助。相关成果发表于Nature Communications、Human Molecular Genetics等学术期刊。

研究领域

1.自闭症谱系障碍候选基因的功能基因组学探索：复杂家系遗传分析，候选基因效应机制及基因编辑修复等干预手段探索。2.大规模测序技术，包括全基因组测序和RNA测序，在临床医学研究中的应用。""

近期论文

1. Lingling Shi, Yunfei Guo, Chengliang Dong, John Huddleston, Hui Yang, Xiaolu Han, Aisi Fu, Quan Li, Na Li, Siyi Gong, Katherine E. Lintner, Qiong Ding, Zou Wang, Jiang Hu, Depeng Wang, Feng Wang, Lin Wang, Gholson J. Lyon, Yongtao Guan, Yufeng Shen, Oleg V. Evgrafov, James A. Knowles, Francoise Thibaud-Nissen, Valerie Schneider, Chack-Yung Yu, Libing Zhou1,Evan E. Eichler, Kwok-Fai So, & Kai Wang. Long-read sequencing and de novo assembly of a Chinese genome. NATURE COMMUNICATIONS. 2016, dx.doi.org/10.1038/NCOMMS120652
2. Lingling Shi, Bingxiao Li, Yonglan Huang, Xueying Ling, Tianyun Liu, Gholson J Lyon, Anding Xu, Kai Wang.“Genotype-first” approaches on a curious case of idiopathic progressive cognitive decline. BMC Med Genomics. 2014, 3;7(1):66.Doi: 10.1186/s12920-014-0066-9.
3. Ling-ling Shi, Xiao Chang, Peilin Zhang, Macello Coba, Wange Lu, Kai Wang. The functional genetic link of NLGN4X knockdown and neurodevelopment in neural stem cells.Human Molecular Genetics. 2013, doi: 10.1093.
4. Ling-ling Shi*, Xu Zhang*, Ryan Golhar, Frederick G Otieno, Mingze He, Cuiping Hou, Cecelia Kim, Brendan Keating, Kai Wang, Hakon Hakonarson. Whole-genome sequencing in an autism multiplex family. Molecular Autism.2013, 4:8 (*: First author) .
5. Liyun Zeng*, Peilin Zhang*, Ling-ling Shi*, Vicky Yamamoto, Wange Lu, Kai Wang. Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models. PLoS ONE. 2013, 8: e59685 (*co-first author).
6. Ling-ling Shi, Fu-ping Liu, De-wen Wang. Transplantation of human umbilical cord blood mesenchymal stem cells improves outcome of rat model of acute hepatic necrosis.Am J Med Sci. 2011, 342(3):212-217 .
7. Gao F, Shi L, Russin J, Zeng L, Chang X, He S, Chen TC, Giannotta SL, Weisenberger DJ, Zada G, Mack WJ, Wang K. DNA Methylation in the Malignant Transformation of Meningiomas. PLoS ONE.2013, 8:e54114.
8. Gao F, Ling C, Shi L, Commins D, Zada G, Mack W, Wang K. Inversion-mediated gene fusions involving NAB2-STAT6 in an unusual malignant meningioma. British Journal of Cancer. 2013, doi: 10.1038/bjc.2013.395.