个人简历

01/2018至今，暨南大学附属第一医院纳米诊疗研究所所长、教授（博导）\r
12/2016至今，暨南大学化学与材料学院副院长、教授（博导）\r
10/2010至今，暨南大学化学系教授（博士生导师）\r
09/2015至今，广东省纳米化学创新药物工程技术研究中心主任\r
12/2008-09/2010，暨南大学化学系副教授（博士生导师）\r
08/2008-08/2009，香港中文大学生物系博士后研究员\r
08/2005–06/2008，香港中文大学生物系博士（化学生物学、细胞生物学）\r
09/2003–06/2005，暨南大学化学系硕士（生物无机化学）\r
09/1999–06/2003，暨南大学化学系学士（应用化学）

研究领域

"""""陈填烽教授一直致力于肿瘤靶向化学创新药物与诊疗应用的研究，获得万人计划青年拔尖人才项目、国家863计划、国家自然科学基金项目、国家科技支撑计划及广东省自然科学杰出青年基金等项目的资助。先后入选了教育部新世纪优秀人才支持计划（2010）、广东省高校“千百十工程”省级培养人才（2012），国家863青年科学家（2013）、广东省杰出青年基金项目（2013）、霍英东青年教师奖（2014）及万人计划青年拔尖人才（2015）。近五年以通讯作者在Cell子刊Matter、Science Advances、JACS、Angew Chem Int Ed、Adv Funct Mater及ACS Nano等本领域主流杂志发表论文超过250篇，其中IF>10有45篇，封面论文38篇，h-index 58，申报中国专利60项，授权美国专利1项，实现技术成果转化12项。担任第六届国际硒研讨会主席、第一届国际富硒产业联盟大会主席。以第一完成人获得2020年中国抗癌协会科技二等奖、2018年中华医学科技奖青年科技奖、2018广东省自然科学二等奖、2017广东省科技进步三等奖、2017中国产学研创新成果奖、2015广州市科技二等奖、2016首届中国创新大赛优秀奖、2014第三届金博奖及2012第七届国际发明展览会银奖，推动了硒化学在生物医药领域的应用。"

近期论文

Weiqiang Lin#, Hongxing Liu#, Lingwu Chen, Junxing Chen, Dong Zhang, Qingqing Cheng, Fang Yang, Qinsong Zeng*, Tianfeng Chen*. Pre-clinical MRI-guided intravesical instillation theranosis of bladder cancer by tumor-selective oxygen nanogenerator, Nano Today, 2021, 38, 101124.\r
\r
Lizhen He#, Guanning Huang#, Hongxing Liu, Chengcheng Sang, Xinxin Liu, Tianfeng Chen*. Highly bioactive zeolitic imidazolate framework-capped nanotherapeutics for efficient reversal of reperfusion-induced injury in ischemic stroke. Science Advances, 2020; 6: eaay9751\r
\r
Wei Huang, Lizhen He, Jiang Ouyang, Qi Chen, Chuang Liu, Wei Tao*, and Tianfeng Chen*. Triangle-Shaped Tellurium Nanostars Potentiate Radiotherapy by Boosting Checkpoint Blockade Immunotherapy. Matter, 2020, 3, 1725-1753.\r
\r
Zhongyang Zhang, Zhongmin Tang, Nika Farokhzad, Tianfeng Chen,* and Wei Tao*. Sensitive, Rapid, Low-Cost, and Multiplexed COVID-19 Monitoring by the Wireless Telemedicine Platform. Matter, 2020, 3, 1818–1831.\r
\r
Leung Chan#, Xiaodan Chen#, Pan Gao, Jun Xie, Zhongyang Zhang, Jianfu Zhao, Tianfeng Chen*. Coordination-Driven Enhancement of Radiosensitization by Black Phosphorus via Regulating Tumor Metabolism. ACS Nano, 2021, 15, 2, 3047\r
\r
Jiang Ouyang, Ling Zhang, Leijiao Li, Zhongmin Tang, Xiaoyuan Ji, Chan Feng, Na Tao, Na Kong, Tianfeng Chen*, You-Nian Liu*, Wei Tao*. Cryogenic Exfoliation of 2D Stanene Nanosheets for Cancer Theranostics. Nano-Micro Letters, 2021, 13:90.\r
\r
Ting Liu#, Ligeng Xu#, Lizhen He, Jianfu Zhao, Zehang Zhang, Qi Chen, Tianfeng Chen*. Selenium Nanoparticles Regulates Selenoprotein to Boost Cytokine-Induced Killer Cells-Based Cancer Immunotherapy. Nano Today, 2020, 35, 100975.\r
\r
Zhuo Wang‡, Lizhen He‡, Bingqing Liu, Li-Peng Zhou, Li-Xuan Cai, Shao-Jun Hu, Xiao-Zhen Li, Zhikai Li, Tianfeng Chen,* Xiaopeng Li,* Qing-Fu Sun*. Coordination-Assembled Water-Soluble Anionic Lanthanide Organic Polyhedra for Luminescent Labeling and Magnetic Resonance Imaging. J. Am. Chem. Soc., 2020, 142, 38, 16409–16419. \r
\r
Hao-Yan Yin, Jiu-Jiao Gao, Xuemin Chen, Bin Ma, Zi-Shu Yang, Juan Tang, Bing-Wu Wang, Tianfeng Chen*, Chu Wang*, Song Gao, Jun-Long Zhang*. A Gallium(III) Complex that Engages Protein Disulfide Isomerase A3 (PDIA3) as an Anticancer Target. Angew Chem Int Edit, 2020, 59, 20147-20153.\r
\r
Liu, Chang; Lai, Haoqiang; Chen, Tianfeng*. Boosting Natural Killer Cell-Based Cancer Immunotherapy with Selenocystine/Transforming Growth Factor-Beta Inhibitor-Encapsulated Nanoemulsion. ACS Nano, 2020, 14, 9, 11067.\r
\r
Jing Wang, Yanzhou Chang, Hui Luo, Wenxiao Jiang, Ligeng Xu, Tianfeng Chen*, Xueqiong Zhu*. Designing Immunogenic Nanotherapeutics for Photothermal-Triggered Immunotherapy Involving Reprogramming Immunosuppression and Activating Systemic Antitumor Responses. Biomaterials, 2020, 120153.\r
\r
Hongxing Liu†, Chaoming Mei†, Xuanru Deng, Weiqiang Lin, Lizhen He, Tianfeng Chen*. Rapid visualizing and pathological grading of bladder tumor tissues by simple nanodiagnostics, Biomaterials, 2021, 264, 120434.\r
\r
Zhennan Zhao, Pan Gao, Li M* and Tianfeng Chen*. A highly X-ray sensitive iridium prodrug for visualized tumor radiochemotherapy. Chemical Science, 2020, 11, 3780 - 3789\r
\r
JuanjuanLi, TianfengChen*. Transition metal complexes as photosensitizers for integrated cancer theranostic applications, Coordination Chemistry Reviews, 2020, 418, 213355.\r
\r
Yuanyuan You, Zhennan Zhao, Lizhen He, Zhibo Sun, Dong Zhang, Changzheng Shi, Qingqing Cheng, Yiyong Liu, Liangping Luo, Tianfeng Chen*. Long-term Oxygen Storage Nanosystem for Near-Infrared Light-Triggered Oxygen Supplies to Antagonize Hypoxia-induced Therapeutic Resistance in Nasopharyngeal Carcinoma. Advanced Functional Materials. 2020, 2002369.\r
\r
Yanyu Huang†, Yuanting Fu†, Mengting Li, Dawei Jiang, Christopher J. Kutyreff, Jonathan W. Engle, Xiaoli Lan, Weibo Cai*, Tianfeng Chen*. Chirality-driven transportation and oxidation prevention by chiral selenium nanoparticles. Angew Chem Int Edit, 2020, 59, 4406-4414. Frontispiece\r
\r
Yanhong Duo#, Yanyu Huang#, Weiyuan Liang#, Riming Yuan, Yang Li, Tianfeng Chen*, Han Zhang*. Ultraeffective Cancer Therapy with an Antimonene-Based X-Ray Radiosensitizer. Advanced Functional Materials. 2019, 1906010.\r
\r
Hongxing Liu, Weiqiang Lin, Lizhen He*, Tianfeng Chen*. Radiosensitive Core/Satellite Ternary Heteronanostructure for Multimodal Imaging-Guided Synergistic Cancer Radiotherapy. Biomaterials, 2020, 119545.\r
\r
Chengli Dai †, ZhengTang †, Xiaoling Li, Tianfeng Chen*. High-pressure homogenization and tailoring of size-tunable Ganoderma lucidum spore oil nanosystem for enhanced anticancer therapy. Chemical Engineering Journal, 2020, 406, 127125\r
\r
Haoqiang Lai, Xiaobin Zhang, Zhenhuan Song, Zhongwen Yuan, Lizhen He*, Tianfeng Chen*. Facile synthesis of antioxidative nanotherapeutics using a microwave for efficient reversal of cisplatin-induced nephrotoxicity. Chemical Engineering Journal, 2020, 391, 123563 \r
\r
Haoqiang Lai, Delong Zeng, Chang Liu, Qi Zhang, and Tianfeng Chen*. Selenium-containing Ruthenium Complex synergizes with Natural Killer Cells to Enhance Immunotherapy Against Prostate Cancer via Activating TRAIL/FasL Signaling, Biomaterials, 2019, 219, 119377\r
\r
Yi Hu#, Ting Liu#, Jingxia Li#, Fengyi Mai, Jiawei Li, Yan Chen, Yanyun Jing, Xin Dong, Li Lin, Junyi He, Yan Xu, Changliang Shan, Jianlei Hao, Zhinan Yin, Tianfeng Chen*, Yangzhe Wu*. Selenium nanoparticles potentiate γδ T cell anti-tumor cytotoxicity by upregulation of tubulin-a acetylation, Biomaterials, 2019, 119397.\r
\r
Lizhen He, Tianqi Nie, Xiaojun Xia, Ting Liu, Yanyu Huang, Xiaojuan Wang, Tianfeng Chen*. Designing Bioinspired 2D MoSe2 Nanosheet for Efficient Photothermal-Triggered Cancer Immunotherapy with Reprogramming Tumor-associated Macrophages. Advanced Functional Materials. 2019, 1901240. (Back Cover)\r
\r
Chengli Dai, Lizhen He, Bin Ma, Tianfeng Chen*. Facile Nanolization Strategy for Therapeutic Ganoderma Lucidum Spore Oil to Achieve Enhanced Protection against Radiation-Induced Heart Disease, Small, 2019, 1902642.\r
\r
Pengju Feng,* Guojian Ma, Xiaoguang Chen, Xing Wu, Ling Lin, Peng Liu and Tianfeng Chen* Electro-oxidative and Regioselective C-H Azolation of Phenol and Aniline Derivatives, Angew Chem Int Edit, 2019, 58, 8400-8404.\r
Chan, Leung ; Gao, Pan ; Zhou, Wenhua ; Mei, Chaoming ; Huang, Yanyu; Yu, Xue-Feng*; Chu, Paul; Chen, Tianfeng*. Sequentially Triggered Delivery System of Black Phosphorus Quantum Dots with Surface Charge Switching Ability for Precise Tumor Radiosensitization. ACS Nano, 2018, 12, 12401–12415.\r
\r
Chaoming Mei, Ni Wang, Xueqiong Zhu, Ka-Hing Wong, Tianfeng Chen*. Photothermal-controlled Nanotubes with Surface Charge Flipping Ability for Precise Synergistic Therapy of Triple-negative Breast Cancer. Advanced Functional Materials. 2018, 1805225.\r
\r
Lizhen He, Tianfeng Chen*, Yuanyuan You, Hao Hu, Wenjie Zheng, Wai-Lun Kwong, Taotao Zou and Chi-Ming Che*. A Cancer-Targeted Nanosystem for Delivery of Anti-Cancer Gold(III) Complexes: Enhanced Selectivity and Apoptosis-Inducing Efficacy of Gold(III) Porphyrin. Angew Chem Int Edit, 2014, 53(46), 12532-12536.\r
\r
Wen Liu, Xiaoling Li, Yum-Shing Wong, Wenjie Zheng*, Yibo Zhang, Wenqiang Cao, Chen Tianfeng*. Selenium nanoparticles as a carrier of 5-Fluorouracil to achieve anticancer synergism. ACS Nano, 2012, 6 (8), 6578–6591.\r
\r
Yanzhou Chang, Lizhen He, Zhibin Li, Lilan Zeng, Zhenhuan Song, Penghui Li, Leung Chan, Yuanyuan You, Xue-Feng Yu*, Paul K Chu, and Tianfeng Chen*. Designing Core-Shell Gold and Selenium Nanocomposites for Cancer Radiochemotherapy. ACS Nano, 2017, 11(5):4848-4858.\r
\r
Lizhen He, Yanyu Huang, Huili Zhu, Guanhua Pang, Wenjie Zheng, Yum-Shing Wong, Tianfeng Chen*. Cancer-targeted Monodisperse Mesoporous Silica Nanoparticles as Carrier of Ruthenium Polypyridyl Complexes to Enhance Theranostic Effects. Advanced Functional Materials. 2014, 24(19), 2754–2763. (封面文章)\r
\r
Ting Liu, Lanhai Lai, Zhenhuan Song, Tianfeng Chen*. A Sequentially triggered nanosystem for precise drug delivery and simultaneous inhibition of cancer growth, migration and invasion. Advanced Functional Materials. 2016, 26, 7775–7790. (Inside Cover)\r
\r
Yuanyuan You, Lizhen He, Bin Ma, Tianfeng Chen*. High-drug loading mesoporous silica nanorods with reduced toxicity for precise cancer therapy against nasopharyngeal carcinoma. Advanced Functional Materials. 2017, 27, 1703313.\r
\r
Wei Huang, Yanyu Huang, Yuanyuan You, Tianqi Nie, Tianfeng Chen*. High-yield synthesis of multifunctional tellurium nanorods to achieve simultaneous chemophotothermal combination cancer therapy. Advanced Functional Materials. 2017, 27, 1701388.\r
\r
Yanyu Huang, Chaoming Mei, Yiqiao Tian, Tianqi Nie, Zhuang Liu*, Tianfeng Chen*. Bioinspired Tumor-homing Nanosystem for Precise Cancer Therapy by Reprogramming Tumor-associated Macrophages. NPG Asia Materials. 2018, 10, 1002–1015.\r
\r
Lan Zheng, Chang’e Li, Xiaoting Huang, Xueran Lin, Weiqiang Lin, Fang Yang*, Tianfeng Chen*. Thermosensitive Hydrogels for Sustained-release of Sorafenib and Selenium Nanoparticles for Localized Synergistic Chemoradiotherapy. Biomaterials, 2019, 216, 119220. \r
\r
Zhennan Zhao#, Xiang Zhang#, Chang-e Li and Tianfeng Chen *. Designing Luminescent Ruthenium Prodrug for Precise Cancer Therapy and Rapid Clinical Diagnosis. Biomaterials, 2019, 192, 579–589.