个人简历

现任暨南大学附属第一医院血液科主任、教授、博士生导师。

研究领域

擅长白血病、淋巴瘤、骨髓瘤的诊治及造血干细胞移植，特别是对于难治复发的急性髓系白血病有比较深入的研究

近期论文

1. Zeng H#, Guo M#, Zhou T, Tan L, Chong CN, Zhang T, Dong X, Xiang JZ, Yu AS, Yue L, Qi Q, Evans T, Graumann J, Chen S*. An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery. Cell Stem Cell. 2016 Sep 1;19(3):326-340.
2. Zeng H#, Park JW, Guo M, Lin G, Crandall L, Compton T, Wang X, Li XJ, Chen FP, Xu RH*. Lack of ABCG2 expression and side population properties in human pluripotent stem cells. Stem Cells. 2009 Oct;27(10):2435-2445.
3. Zhang J#, Huang FF, Wu DS, Li WJ, Zhan HE, Peng MY, Fang P, Cao PF, Zhang MM, Zeng H*, Chen FP*.SUMOylation of insulin-like growth factor 1 receptor, promotes proliferation in acute myeloid leukemia. Cancer Lett. 2015 Feb 1;357(1):297-306.
4. Huang FF#, Wu DS, Zhang L, Yu YH, Yuan XY, Li WJ, Chen XP, Zhao XL, Chen FP*, Zeng H*. Inactivation of PTEN increases ABCG2 expression and the side population through the PI3K/Akt pathway in adult acute leukemia. Cancer Lett. 2013 Aug 9;336(1):96-105.
5. Yu YH#, Wu DS, Huang FF, Zhang Z, Liu LX, Zhang J, Zhan HE, Peng MY, Zeng H*, Chen FP*.MicroRNA-20b and ERK1/2 pathway independently regulate the expression of tissue factor in hematopoietic and trophoblastic differentiation of human embryonic stem cell. Stem Cell Res Ther. 2013 Oct 11;4(5):121.
6. Liang H#, Zheng QL, Fang P, Zhang J, Zhang T, Liu W, Guo M, Robinson CL, Chen SB, Chen XP, Chen FP*, Zeng H*. Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells. Sci Rep. 2017 Jan 18;7:40361.
7. Zeng H#, Guo M#, Martins-Taylor K, Wang X, Zhang Z, Park JW, Zhan S, Kronenberg MS, Lichtler A, Liu HX, Chen FP, Yue L, Li XJ, Xu RH*.Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells. PLoS One. 2010 Jul 29;5(7):e11853.
8. Yu YH#, Zhang L, Wu DS, Zhang Z, Huang FF, Zhang J, Chen XP, Liang DS, Zeng H*, Chen FP*.MiR-223 regulates human embryonic stem cell differentiation by targeting the IGF-1R/Akt signaling pathway. PLoS One. 2013 Nov 8;8(11):e78769.
9. Huang FF#, Zhang L, Wu DS, Yuan XY, Yu YH, Zhao XL, Chen FP*, Zeng H*.PTEN regulates BCRP/ABCG2 and the side population through the PI3K/Akt pathway in chronic Myeloid leukemia. PLoS One. 2014 Mar 6;9(3):e88298.
10．Zhang DY#, Yan H, Cao S, Zhang W, Li XL, Zeng H*, Chen XP*.Wilms tumor 1 rs16754 predicts favorable clinical outcomes for acute myeloid leukemia patients in south chinese population. Leuk Res. 2015 Jun;39(6):568-574.