个人简历

2002年9月南京大学生命科学院生物技术（生化药学强化班）学习，2006年7月获理学学士学位。2006年9月保送南京大学模式动物研究所硕博连读，2011年6月获生物学博士学位。2011年6月至今，江南大学医药学院、药学院、任讲师、副教授、硕士生导师。2015年8月至2017年8月，美国洛杉矶西达-赛奈医疗中心（Cedars-Sinai   Medical Center）医学部博士后。

研究领域

纤维化疾病发病机制研究、肠道微生物与炎性肠病及纤维化疾病的关联研究

近期论文

[1] Ren Y, Geng Y*, Du Y, Li W, Lu ZM, Xu HY, Xu GH, Shi JS, Xu ZH*. Polysaccharide of Hericium erinaceus Attenuates Colitis in C57BL/6 Mice via regulation of oxidative stress, inflammation-related signaling pathways and modulating the composition of the gut microbiota. J Nutr Biochem, 2018, 57:67-76. doi: 10.1016/j.jnutbio.2018.03.005. (*Corresponding author)
[2] Xie T, Wang Y, Deng N, Huang G, Taghavifar F, Geng Y, Liu N, Kulur V, Yao C, Chen P, Liu Z, Stripp B, Tang J, Liang J, Noble PW, Jiang D. Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis. Cell Rep. 2018 Mar 27;22(13):3625-3640. doi: 10.1016/j.celrep.2018.03.010.
[3] Xie T, Liang J, Geng Y, Liu N, Kurkciyan A, Kulur V, Leng D, Deng N, Liu Z, Song J, Chen P, Noble PW, Jiang D. MicroRNA-29c Prevents Pulmonary Fibrosis by Regulating Epithelial Cell Renewal and Apoptosis. Am J Respir Cell Mol Biol. 2017 Dec;57(6):721-732. doi: 10.1165/rcmb.2017-0133OC.
[4] Geng Y, Zhu S, Cheng P, Lu Z M, Xu H Y, Shi J S and Xu Z H. Bioassay-guided fractionation of ethyl acetate extract from Armillaria mellea attenuates inflammatory response in lipopolysaccharide (LPS) stimulated BV-2 microglia. Phytomedicine, 2017,26:55-61.
[5] Geng Y, Sun Q, Li W, Lu Z M, Xu H Y, Shi J S and Xu Z H. The common dietary flavonoid myricetin attenuates liver fibrosis in carbon tetrachloride-treated mice. Molecular Nutrition & Food Research, 2017;61(4). DOI 10.1002/mnfr.201600392
[6] Liang J, Zhang Y, Xie T, Liu N, Chen H, Geng Y, Kurkciyan A, Mena JM, Stripp BR, Jiang D, Noble PW. Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice. Nat Med. 2016, 22(11):1285-1293.
[7] Li X, Fang Y, Li X, Liang J, Jiang D, Geng Y*, Ning W*. Apical Secretion of FSTL1 in the Respiratory Epithelium for Normal Lung Development. PLoS One, 2016, 29;11(6):e0158385. (*corresponding author)
[8] Geng Y, Wang J, Sun Q, Xie M, Lu Z M, Xu H Y, Shi J S, Xu Z H. Identification of Antrodin B from Antrodia camphorata as a new anti-hepatofibrotic compound using a rapid cell screening method and biological evaluation. Hepatol Res, 2016, 46(3):E15-25.
[9] Dong Y*, Geng Y*, Li L*, Li X, Yan X, Fang Y, Dong S, Liu X, Yang X, Zheng X, Xie T, Liang J, Dai H, Yin Z, Noble P W, Jiang D, Ning W. Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice. J Exp Med, 2015, 212(2): 235-252. (*Co-First author)
[10] Geng Y, Wang J, Xie M, Lu Z, Xu H, Shi J S, Xu Z H. Screening and isolation for anti-hepatofibrotic components from medicinal mushrooms using TGF-beta1-induced live fibrosis in hepatic stellate cells. Int J Med Mushrooms, 2014, 16(6): 529-539.
[11] Geng Y, Zhu S, Lu Z, Xu H, Shi J S, Xu Z H. Anti-inflammatory activity of mycelial extracts from medicinal mushrooms. Int J Med Mushrooms, 2014, 16(4): 319-325.
[12] Geng Y, Li L, Dong Y, Liu X, Li X H, Ning W. Impaired elastin deposition in Fstl1-/- lung allograft under the renal capsule. PLoS One, 2013, 8(11): e81368.
[13] Geng Y, He Z, Lu Z M, Xu H Y, Xu G H, Shi J S, Xu Z H. Antrodia camphorata ATCC 200183 sporulates asexually in submerged culture. Appl Microbiol Biotechnol, 2013, 97(7): 2851-2858.
[14] Geng Y, Lu Z M, Huang W, Xu H Y, Shi J S, Xu Z H. Bioassay-guided isolation of DPP-4 inhibitory fractions from extracts of submerged cultured of Inonotus obliquus. Molecules, 2013, 18(1): 1150-1161.
[15] Geng Y, Dong Y, Yu M, Zhang L, Yan X, Sun J, Qiao L, Geng H, Nakajima M, Furuichi T, Ikegawa S, Gao X, Chen Y G, Jiang D, Ning W. Follistatin-like 1 (Fstl1) is a bone morphogenetic protein (BMP) 4 signaling antagonist in controlling mouse lung development. Proc Natl Acad Sci USA, 2011, 108(17): 7058-7063.