个人简历

1978年3月生，教授、博士生导师。主要从事食品微生物学及分子生物学相关领域的教学和科研工作，研究方向为食品微生物功能发掘与利用，研究工作围绕食品微生物产功能多不饱和脂肪酸、产功能蛋白及多肽的研究及应用展开。主持承担国家自然科学基金、国家“863” 课题等科研项目10余项，2013年入选教育部新世纪优秀人才计划，2014年入选江苏省“六大人才高峰”计划，同时是教育部创新团队发展计划的骨干。在国内外食品微生物领域学术期刊上发表学术论文72篇，其中SCI收录论文47篇，发表杂志包括Appliedand Environmental Microbiology, Scientific Reports, Microbiology-Sgm等，h指数为12，发表文章被Science,JACS, Biotechnology advances 等顶级期刊引用。申请发明专利共28项（包括美国专利2项），13项已授权（其中美国专利1项）。研究成果申获教育部科技进步一等奖、中国商业联合会科学技术一等奖各一项。

受教育经历
2011-2012 美国WakeForest University医学院脂质研究中心 博士后
2001-2006 浙江大学材化学院 生物工程专业 博士
1997-2001 浙江大学化工系 生物化工专业 学士
研究工作经历
2013 - 至 今 江南大学 食品学院 教授、博导
2007 - 2013 江南大学 食品学院 副教授、硕导
2006 -2007 江南大学 食品学院 校聘副教授

研究领域

从事食品微生物学及分子生物学相关领域的教学和科研工作，研究方向为食品微生物功能发掘与利用，研究工作围绕食品微生物产功能多不饱和脂肪酸、产功能蛋白及多肽的研究及应用展开

近期论文

[1] ChenH, Hao G, Wang L,Wang H, Gu Z, Liu L, Zhang H, Chen W*, Chen Y Q*. Identification of a criticaldeterminant that enables efficient fatty acid synthesis in oleaginous fungi. ScientificReports, 2015, 5: 11247.
[2] YangB, Chen H*, Stanton C, Ross RP, Zhang H, Chen Y Q, Chen W*. Review of the roles of conjugated linoleic acidin health and disease, Journal of Functional Foods, 2015, 15: 314-325.
[3] DongYN, Chen H*, Sun YH, Zhang H,Chen W. A differentially conserved residue (Ile42) of GH42 β-galactosidase fromGeobacillus stearothermophilus BgaB is involved in both catalysis and thermostability.J Dairy Sci. 2015; 98(4):2268-76
[4] Tang X, ChenH, Chen Y Q, Chen W, Garre V, Song Y*, Ratledge C. Comparison ofBiochemical Activities between High and Low Lipid-Producing Strains of Mucorcircinelloides: An Explanation for the High Oleaginicity of Strain WJ11[J].PLoS ONE, 2015, 10(6): e0128396.
[5] Ye C, Xu N, Chen H, Chen YQ, Chen W, Liu L*. Reconstruction and analysisof a genome-scale metabolic model of the oleaginous fungus Mortierella alpina. BMCSyst Biol. 2015;9(1):1
[6] Wang G, Xia Y, Cui J, Gu Z, Song Y, Chen YQ,Chen H*, Zhang H, Chen W*.The roles of moonlighting proteins in Bacteria. Current Issues MolecularBiology. 2014, 16:15-22
[7] Hao G, ChenH*, Du K, Huang X, Song Y, Gu Z, Wang L, Zhang H, Chen W, Chen YQ.Increased fatty acid unsaturation and production of arachidonic acid byhomologous over-expression of the mitochondrial malic enzyme in Mortierellaalpina. Biotechnology Letters. 2014, 36( 9):1827-1834
[8] Hao G#, ChenH#, Wang L, Gu Z, Song Y, Zhang H, Chen W*, Chen YQ*. Role of MalicEnzyme during Fatty Acid Synthesis in the Oleaginous Fungus Mortierella alpina.Applied and Environmental Microbiology. 2014, 80(9):2672-2678.
[9] Yang B, ChenH*, Gu Z, Tian F, Ross RP, Stanton C, Chen YQ, Chen W, Zhang H. Synthesisof conjugated linoleic acid by the linoleate isomerase complex in food-derivedlactobacilli. J Appl Microbiol. 2014;117(2):430-9
[10] Tang X, Zhang H, Chen H, Chen YQ, Chen W, Song Y*. Effects of 20 StandardAmino Acids on the Growth, Total Fatty Acids Production, and γ-Linolenic AcidYield in Mucor circinelloides. Curr Microbiol. 2014, 69(6):899-908.
[11] Zhang H, Zhang L, Chen H, Chen YQ, Chen W, Song Y*, Ratledge C. Enhanced lipidaccumulation in the yeast Yarrowia lipolytica by over-expression of ATP:citratelyase from Mus musculus. J Biotechnol. 2014;192PA:78-84.
[12] Wang G, Zhao Y, Tian F, Jin X，ChenH，Liu X，Zhang Q, Zhao J, Chen YQ, Zhang H, Chen W*. Screening of adhesive lactobacilli with antagonistic activity againstCampylobacter jejuni. Food Control. 2014, 44: 49-57
[13] Yang J, Hu X, Zhang H, Chen H, Kargbo MR, Zhao J, Song Y*, Chen YQ, Zhang H, Chen W*.Expression, Purification, and Characterization ofNADP(+)-Dependent Malic Enzymefrom the Oleaginous Fungus Mortierella Alpina. Applied Biochemistry andBiotechnology. 2014, 173(7): 1849-1857
[14] ChenH, Gu Z, Zhang H,Wang M, Chen W, Lowther WT, Chen YQ*: Expression and purification of integralmembrane fatty acid desaturases. PLoS ONE 2013, 8(3):e58139.
[15] Wang M, ChenH*, Gu Z, Zhang H, Chen W, Chen YQ. Omega3 fatty acid desaturases frommicroorganisms: structure, function, evolution, and biotechnological use.Applied microbiology and biotechnology. 2013, 97:10255–10262
[16] Zhang B#, Chen H#, Li M, Gu Z, Song Y, Ratledge C, Chen YQ, Zhang H*,Chen W*. Genetic engineering of Yarrowia lipolytica for enhanced production oftrans-10, cis-12 conjugated linoleic acid. MICROBIAL CELL FACTORIES. 2013,12:70
[17] Yang B, ChenH*, Song Y, Chen Y, Zhang H, Chen W: Myosin-cross-reactive antigensfrom four different lactic acid bacteria are fatty acid hydratases.Biotechnology Letters 2013, 35(1):75-81.
[18] Wang H, ChenH*, Hao G, Yang B, Feng Y, Wang Y, Feng L, Zhao J, Song Y, Zhang H, ChenY, Chen W*: Role of the Phenylalanine-Hydroxylating System in AromaticSubstance Degradation and Lipid Metabolism in the Oleaginous Fungus Mortierellaalpina. Applied and Environmental Microbiology 2013, 79(10):3225-3233.
[19] Dong Y#, Wang L#, Gu Q, Chen H*, Liu X, Song Y, Chen W, Hagler A, Zhang H, Xu J*:Optimizing lactose hydrolysis by computer-guided modification of the catalyticsite of a wild-type enzyme. Molecular Diversity 2013, 17(2):371-382.
[20] Wang G, ChenH, Zhang H, Song Y*, Chen W*. The Secretion of an IntrinsicallyDisordered Protein with Different Secretion Signals in Bacillus subtilis.Current Microbiology. 2013, 66:566–572