个人简历
徐华丽（1977.10- ），博士， 1995级白求恩医科大学医药信息专业（本科），2003年7月获药理学硕士学位，2009年7月获药理学博士学位。2003年9月至2004年8月到日本福冈大学进修一年，2010年1月至2012年8月到美国Morehouse School of Medicine (佐治亚州肿瘤研究中心) 从事博士后研究工作。2003年硕士毕业后留吉林大学药学院药理教研室任教，2006年9月晋级讲师。发表论文21篇，其中SCI论文12篇（第一作者7篇），核心期刊论文13篇（第一作者3篇），参编国家规划教材1部，参编专著1部。承担及参加了省部级及以上课题5项，其中作为项目负责人承担省级课题2项，作为主要参加人参与国家自然科学基金项目1项和省级项目2项，纵向课题负责人3项，共计获得经费66万。现为吉林省药理学会和吉林省保健品学会委员。
研究领域
1. 药物诱导肿瘤凋亡的机制 2. 药物诱导肿瘤自噬的机制 3. 肿瘤细胞上皮间质化
近期论文
1. Hong Zhang, Hua-Li Xu, Wen-wen Fu, Ying Xin, Mao-Wei Li, Shuai-Jun Wang, Xiao-Feng Yu , Da-Yun Sui. 20(S)-Protopanaxadiol Induced Human Breast Cancer MCF-7 Apoptosis through Caspase-Mediated Pathway[J]. Asian Pac J Cancer Prev. Accept. （共同第一作者) 2. ZHANG Peng, SUI Dayun, XU Huali, SUN Weilun, YU Xiaofeng, QU Shaochun, HU Jianbing, WU Yi1 and WANG Yingshi. Synthesis and Antitumor Activity of a New 7-Azaindole Derivative[J]. Chem. Res. Chin. Univ. 2014,30(3),420-424 3. Xu H, Yu X, Qu S, Chen Y, Wang Z, Sui D. Protective effect of Panax quinquefolium 20(S)-protopanaxadiol saponins, isolated from Pana quinquefolium, on permanent focal cerebral ischemic injury in rats[J]. Exp Ther Med. 2014;7(1): 165-170. 4. Zhang YL, Zhang R, Xu HL, Yu XF, Qu SC, Sui DY. 20(S)-protopanaxadiol triggers mitochondrial-mediated apoptosis in human lung adenocarcinoma A549 cells via inhibiting the PI3K/Akt signaling pathway[J]. Am J Chin Med. 2013;41(5): 1137-52 5. Jiao SUN, Huali XU, Xiaofeng YU, Shaochun QU, Dayun SUI, Li WANG Protective Effects of Ginsenoside Rb3 on Acute Myocardial Ischemia in Rats Through Inhibition of the Sympathetic-Adrenal Medulla System[J]. Lat. Am. J. Pharm. 2013 ; 32 (10): 1439-44（共同第一作者） 6. Xu H, Yu X, Qu S, Sui D. Juglone, isolated from Juglans mandshurica Maxim, induces apoptosis via down-regulation of AR expression in human prostate cancer LNCaP cells[J]. Bioorg Med Chem Lett, 2013;23:3631-4. 7. Xu H, Yu X, Qu S, Chen Y, Wang Z, Sui D. In vive and in vitro cardioprotective effects of panax quinquefolium 20(S)-protopanaxadiol saponins (PQDS), isolated from panax quinquefolium[J]. Pharmazie, 2013;68(4):287-92. 8. Hua Li Xu, Xiao Feng Yu, Shao Chun Qu, Xiang Ru Qu, Yan Fang Jiang, Da Yuan Sui. Juglone, from Juglans mandshruica Maxim, inhibits growth and induces apoptosis in human leukemia cell HL-60 through a reactive oxygen species-dependent mechanism [J]. Food and Chemical Toxicology, 2012; 50(3): 590-596. 9. Xu HL, Yu XF, Qu SC, Zhang R, Qu XR, Chen YP, Ma XY, Sui DY. Anti-proliferative effect of Juglone from Juglans mandshurica Maxim on Human leukemia cell HL-60 by inducing apoptosis through the mitochondria-dependent pathway [J]. Eur J Pharmacol, 2010; 645(1-3):14-22. 10. Qu X, Qu S, Yu X, Xu H, Chen Y, Ma X, Sui D. pseudo-G-Rh2 induces mitochondrial-mediated apoptosis in SGC-7901 human gastric cancer cells[J]. Oncol Rep, 2011;26(6):1441-1446. 11. Fortson WS, Kayarthodi S, Fujimura Y, Xu H, Matthews R, Grizzle WE, Rao VN, Bhat GK, Reddy ES.Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells[J]. Int J Oncol, 2011;39(1):111-119. 12. Wang T, Yu X, Qu S, Xu H, Han B, Sui D. Effect of ginsenoside Rb3 on myocardial injury and heart function impairment induced by isoproterenol in rats [J]. Eur J Pharmacol, 2010; 25;636(1-3):121-125.
