个人简历

王迪，2009年在吉林大学生命科学学院获得硕士学位后，进入香港大学李嘉诚医学院学习，2013年获得博士学位。现任吉林大学生命科学学院教授，博士生导师，生物国家级实验教学示范中心副主任，国家中药制剂三级实验室副主任。主要从事天然产物功效筛选及作用机制的研究，中药、生物药大品种的二次开发。近5年来，以第一责任作者，在Molecular Cancer，CARBOHYDRATE POLYMERS, Cell Death & Disease，Cancers， Expert Opinion on Drug Delivery，International Journal of Biological Macromolecules等国际期刊发表SCI论文108篇，获得国家授权发明专利15件（转化2件），编著教材4部，承担包括政府间国际科技创新合作重点专项、国家自然科学基金、吉林省“双十工程”重大科技成果转化项目、吉林省重点科技攻关项目、吉林省医药健康专项、吉林省产业技术研究与开发专项在内的国家、省部级等项目14项目，累计科研经费超过800万元。2015年获得吉林省自然科学学术成果一等奖，同年作为骨干成员被评为吉林省首批重大科技项目研发人才团队，2017年获得吉林大学优秀青年教师培养计划项目支持。2018年获得高等教育国家级教学成果奖二等奖。
代表性承担项目
1. 国家重点研发计划，SQ2018YFGH000047，2019.6-2021.5, 476万元（子课题50万元）
2. 国家青年自然科学基金，81402955，2015.1-2017.12，23万元；
3. 吉林省省校共建计划专项项目，SXGJSF2017-1，2017.7-2020.7, 3400万元（子课题200万元）；
4. 横向课题，2016.10-2035.10，150万元；
5. 横向课题，2019.11-2033.10, 80万元；
6. 吉林省重大科技攻关招标项目，20150203002NY，2015.1-2017.12，75万元
7. 吉林省“双十工程”重大科技成果转化项目，20140301003YY，2014.1-2016.12，40万元
8. 吉林省“双十工程”重大科技成果转化项目，20130201006ZY，2013.12-2015.12，60万元；
教育经历： 2003年9月-2007年7月：吉林大学，生物科学 学士
2007年9月-2009年7月：吉林大学，生物化学与分子生物学，硕士 (免试；提前一年毕业)
2009年9月-2013年9月：香港大学，药理学，博士（全额奖学金）
工作经历： 2017年9月～现在：吉林大学，生命科学学院，教授；
2015年9月～2017年9月：吉林大学，生命科学学院，副教授；
2013年9月～2015年9月：吉林大学，生命科学学院，讲师；
荣誉称号： 2018年高等教育国家级教学成果奖，二等奖
2015年吉林省首批重大科技项目研发人才团队骨干成员；
2015年吉林省自然科学学术成果，一等奖；
2017-2020年吉林大学优秀青年教师培养计划；
2018年度吉林大学“课题教学质量”优秀奖；

研究领域

1. 大型食药用真菌发酵、功效筛选及机制研究；; 2. 天然化合物的功效筛选及药理机制研究; 3. 中药、生物药的二次开发；""

近期论文

1) Di Wang, Heikiu Wong, Li Zhang, Grainne M. McAlonan, Xiaomin Wang, Stephen Cho Wing Sze, Yibin Feng, Zhangjin Zhang*. Not only dopamine D2 receptors involved in Peony-Glycyrrhiza Decoction, an herbal preparation against antipsychotic-associated hyperprolactinemia. Progress in Neuro-Psychopharmacology and Biological Psychiatry 39:332-338, 2012.( IF: 4.315) （2区）
2) Di Wang, Yating Sun, Yange Liu, Robert Lee*, Lesheng Teng*. Clinical Translation of Immunoliposomes for Cancer Therapy: Recent Perspectives, Expert Opinion on Drug Delivery. 2018, 15(9): 893-903 (IF: 5.4). （2区）
3) Di Wang#, Xue Jiang#, Shanshan Teng, Yaqin Zhang, Yang Liu, Xiao Li*, Yu Li*. The Antidiabetic and Antinephritic Activities of Auricularia cornea (an albino mutant strain) via Modulation of Nrf2-mediated Oxidative Stress in the db/db mouse. Frontiers in Immunology. 2019. 10:1039. doi: 10.3389/fimmu.2019.01039 (IF: 5.085) （2区）
4) Ning Wang, Hor-Yue Tan, Sha Li, Di Wang, Yu Xu, Cheng Zhang, Wen Xia, ChiMing Che, Yibin Feng*, SBP2 deficiency in adipose tissue macrophages drives insulin resistance in obesity, Science Advances 2019, 5(8): 10.1126/sciadv.aav0198 (IF: 13.116) （1区）
5) Jiawei He, Anhui Yang, Xuyu Zhao, Yang Liu, Shuyan Liu*, Di Wang* Anti-Colon Cancer Activity of Water-Soluble Polysaccharides Extracted from Gloeostereum incarnatum via Wnt/β-catenin Signaling Pathway. Food Science and Human Wellness 2020 (Acceptted) (IF: 2.455) （2区）
6) Yange Liu, Zhuqian Wang, Fange Kong, Lesheng Teng, Xingkai Liu*, Di Wang*. Triterpenoid separated from Antrodia cinnamomea mycelia ameliorates acute alcohol-induced liver injury via regulating HIF-1 alpha. Frontiers in Microbiology (Acceptted) (IF: 4.235) （2区）
7) Lanzhou Li, Xue Jiang, Shanshan Teng, Lesheng Teng*, Di Wang* Calf Thymus Polypeptide Improved Hemopoiesis via G-CSF and M-CSF Related Passway in Hematopoietic Dysfunction Mice. 2020 International Journal of Biological Macromolecules, 2020, 156:204-216 (IF: 5.162). （1区）
8) Yidi Qu, Hor-Yue Tan, Yau-Tuen Chan, Hongbo Jiang, Ning Wang*, Di Wang*, The functional role of long noncoding RNA in the resistance to anticancer, 2020, Therapeutic Advances in Medical Oncology, 2020, 12:1-18 (IF: 6.852) （2区）
9) Bo Dou#, Wenji Hu#, Minkai Song, Robert J Lee*, Xiaoyu Zhang*, Di Wang*, Anti-inflammation of Erianin in dextran sulfate sodium-induced ulcerative colitis mice model via collaborative regulation of TLR4 and STAT3 Chemico-Biological Interactions, 2020, 324:109089. (IF: 3.723) （2区）
10) Xue Jiang, Weiqi Meng, Lanzhou Li, Zhaoli Meng*, and Di Wang *, Adjuvant Therapy of mushroom Polysaccharides on Diabetic Complications, Frontiers in Pharmacology, 2020，168: Article 168 (IF: 4.225) （2区）
11) Yutong Li, Yongfeng Zhang, Xinrui Zhang, Wenqian Lu, Jiawei He, Xin Liu, Min Hu*, Di Wang*. Aucubin exerts anti-osteoporotic effects by promoting osteoblast differentiation. Aging-us, 2020 12(3):2226-2245 (IF: 4.831) （2区）
12) Wenji Hu#, Juan Wang#, Weiying Guo#, Yange Liu, Ziang Guo, Yuge Miao, Di Wang*. Studies on characteristics and anti-diabetic and -nephritic effects of polysaccharides isolated from Paecilomyces Hepiali fermentation mycelium in db/db mice Carbohydrate polymers, 2020 Mar 15;232:115766 (IF:7.182) （1区）
13) Zhuqian Wang, Yange Liu, Tianjiao Cao, Shuyan Liu, Yang Liu*, Di Wang*. Aronia melanocarpa prevents alcohol-induced chronic liver injury via regulation Nrf2 signaling in mice. Oxidative Medicine and Cellular Longevity, 2020, Article ID 4054520, 13 pages (IF: 5.076) （2区）
14) Xinrui Zhang, Yingwu Wang, Xin Li , Anhui Yang, Zhiwen Li*, Di Wang*. The anti-carcinogenesis properties of erianin in the modulation of oxidative stress-mediated apoptosis and immune response in liver cancer. Aging-us, 2019, 11: 102456 (IF: 4.831) （2区）
15) Chang Yang, Qi Feng, Huan Liao, Xinlei Yu, Yang Liu*, Di Wang*. Anti-diabetic nephropathic activities of polysaccharides obtained from Termitornyces albuminosus via regulation NF-κB signaling in db/db mice. International Journal of Molecular Sciences, 2019,20:5205 (IF: 4.556) （2区）
16) Bo Meng, Yuanzhu Zhang, Zhuqian Wang, Yan Du, Ding qinran, Jia Song*, Di Wang*, Hepatoprotective Effects of Morchella esculenta against Alcohol-induced Acute Liver Injury in the C57BL/6 mouse via the Modulation of Nrf-2/NF-κB Signaling. Oxidative Medicine and Cellular Longevity. 2019 doi: 10.1155/2019/6029876. eCollection 2019. (IF: 5.076) （2区）
17) Xue Jiang#, Hor-Yue Tan#, Shengsheng Teng, Yau-Tuen Chan, Di Wang*, Ning Wang*, The role of AMP-Activated Protein Kinase as a potential target of treatment of hepatocellular carcinoma. Cancers, 2019, 11,647. Doi:10.3390/cancers11050647 (IF: 6.126) （2区）
18) Yange Liu, Juan Wang, Xinrui Zhang, Li Wang, Tian Hao, Yanli Cheng*, Di Wang, Scutellarin Exerts Hypoglycemic and Renal Protective Effects in db/db mice via Nrf2/HO-1 signaling Pathway. Oxidative Medicine and Cellular Longevity, 2019, Article ID 1354345, 12 pages. (IF: 5.076) （2区）
19) Yidi Qu, Bo Dou, Hor Yue Tan, Yibin Feng*, Ning Wang* Di Wang*, Tumor microenvironment-driven non-cellautonomous resistance to antineoplastic treatment, Molecular Cancer, 2019, 16:69 (IF: 15.302) （1区）
20) Zhuqian Wang, Xi Wang, Han Yan, Yan Liu, Lanzhou Li, Shaopeng Li, Xiaofeng Wang, Di Wang. Aronia melanocarpa ameliorates gout and hyperuricemia in animal models, Food and Agricultural Immunology, 2019, 30 (1): 47-59 (IF: 2.398) （2区）
21) Zhiping Li, Xia Chen, Yongfeng Zhang, Xin Liu, Chunyue Wang, Lesheng Teng, Di Wang. Protective roles of Amanita caesarea polysaccharides against Alzheimer's disease via Nrf2 pathway. International Journal of Biological Macromolecules, 2019, 121:29-37 (IF: 5.162) （1区）
22) Xue Wang, Zhuqian Wang, Honghong Wu, Wei Jia, Lesheng Teng, Jia Song, Xige Yang*, Di Wang*. Sarcodon imbricatus polysaccharides protect against cyclophosphamide-induced immunosuppression via regulating Nrf2-mediated oxidative stress. International Journal of Biological Macromolecules, 2018, 12: 736-744 (IF: 5.162) （1区）
23) Xinrui Zhang, Mengya Wang, Shanshan Teng, Di Wang, Xin Li, Xiaofeng Wang*, Weiwei Liao*, Di Wang*. Indolyl-chalcone derivatives induce hepatocellular carcinoma cells apoptosis through oxidative stress related mitochondrial pathway in vitro and in vivo. Chemico-Biological Interactions, 2018, 293 (25):61-69 (IF: 3.723) （2区）
24) Xue Wang, Qiubo Chu, Xue Jiang, Yue Yu, Libian Wang, Yaqi Cui, Jiahui Lu, Lirong Teng*, Di Wang* Sarcodon imbricatus polysaccharides improve mouse hematopoietic function after cyclophosphamide induced damage via G-CSF mediated JAK2/STAT3 pathway, Cell Death & Disease, 2018, 21;9(6):578. (IF: 6.34) （2区）
25) Yongfeng Zhang, Jiaqi Wang, Chunyue Wang, Zhiping Li, Xin Liu, Jun Zhang, Jiahui Lu, Di Wang*, Pharmacological Basis for Use of Evodiamine in Alzheimer's Disease: Antioxidation, Antiapoptosis and Neurotransmitters Regulation. International Journal of Molecular Sciences, 2018. doi: 10.3390/ijms19051527 (IF:4.183) （2区）
26) Xue Jiang, Shanshan Teng, Xue Wang, Shan Li, Yaqin Zhang, Di Wang*. The Antidiabetic and Antinephritic Activities of Tuber melanosporum via Modulation Nrf2-mediated Oxidative Stress in the db/db mouse. Oxidative Medicine and Cellular Longevity, 2018 Artivle ID 7453865 (IF: 5.076) （2区）
27) Xue Wang, Yidi Qu, Yongfeng Zhang, Shaopeng Li, Yiyang Sun, Zepeng Chen, Lirong Teng*, Di Wang*, Antifatigue Potential Activity of Sarcodon imbricatus in Acute Excise-Treated and Chronic Fatigue Syndrome in Mice via Regulation of Nrf2-Mediated Oxidative Stress. Oxidative Medicine and Cellular Longevity, 2018 Article ID 9140896, 13 pages (IF: 5.076). （2区）
28) Yange Liu, Anhui Yang, Yidi Qu, Zhuqian Wang, Yuqi Zhang, Yan Liu, Ning Wang, Lirong Teng*, Di Wang*. Ameliorative Effects of Antrodia cinnamomea Polysaccharides Against Cyclophosphamide-Induced Immunosuppression Related to Nrf2/HO-1 Signaling in BALB/c Mice. International Journal of Biological Macromolecules, 2018, 116: 8-15 (IF: 5.162) （1区）
29) Yutong Li, Wenji Hu, Guanghong Han, Wenqian Lu, Dongxu Jia, Min Hu* Di Wang*, Involvement of bone morphogenetic protein–related pathways in the effect of aucubin on the promotion of osteoblast differentiation in MG63 cells. Chemico-Biological Interactions, 2018, 283:51-58. (IF: 3.407) （2区）
30) Xinrui Zhang#, Yilin Chen#, Guangsheng Cai#, Xin Li, Di Wang*. Carnosic acid induces apoptosis of hepatocellular carcinoma cells via ROS-mediated mitochondrial apoptosis pathway. Chemico-Biological Interactions. 2017, 277:91-100. (IF: 3.296) （2区）
31) Zhiping Li, Xia Chen*, Wenqian Lu, Shun Zhang, Xin Guan, Zeyu Li, Di Wang*. Anti-Oxidative Stress Activity Is Essential for Amanita caesarea Mediated Neuroprotection on Glutamate-Induced Apoptotic HT22 Cells and an Alzheimer’s Disease Mouse Model. International Journal of Molecular Sciences 2017, 18: 1623. (IF:3.687) （2区）
32) Shengshu An, Wenqian Lu, Yongfeng Zhang, Qingxia Yuan, Di Wang*. Pharmacological Basis for Use of Armillaria mellea Polysaccharides in Alzheimer's Disease: Antiapoptosis and Antioxidation. Oxidative Medicine and Cellular Longevity, 2017: Article ID 4184562, 11 pages (IF: 5.076). （2区）
33) Yange Liu, Juan Wang Lanzhou Li, Wenji Hu, Yidi Qu, Yipei Ding, Lina Meng, Lirong Teng*, Di Wang*. Hepatoprotective Effects of Antrodia cinnamomea: The Modulation of Oxidative Stress Signaling in a Mouse Model of Alcohol-Induced Acute Liver Injury. Oxidative Medicine and Cellular Longevity, 2017, Article ID 7841823, 12 pages. (IF: 5.076) （2区）
34) Junrong Zhang, Shengshu An, Wenji Hu, Meiyu Teng, Xue Wang, Yidi Qu, Yang Liu, Ye Yuan, Di Wang*. The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model. International Journal of Molecular Sciences, 2016, 17:1810. (IF: 3.226) （2区）
35) Na Qu, Robert J Lee, Yating Sun, Guangsheng Cai, Junyang Wang, Jiahui Lu, Qiangfan Meng, Di Wang*, Lesheng Teng*, Cabazitaxel-loaded human serum albumin nanoparticles as a therapeutic agent against prostate cancer. International Journal of Nanomedicine, 2016, 11:3451-3459 (IF:4.3) （2区）
36) Chungang Liu, Jingjing Song, Meiyu Teng, Xiaoyi Zheng Xiangmei Li, Yue Tian, Minlian Pan, Yuhuan Li, Robert J. Lee*, Di Wang*. Antidiabetic and Antinephritic Activities of Aqueous Extract of Cordyceps militaris Fruit Body in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Oxidative Medicine and Cellular Longevity, 2016. Article ID 9685257, 11 pages, doi:10.1155/2016/9685257 (IF: 5.076) （2区）
37) Jingjing Song, Yingwu Wang, Chungang Liu, Yan Huang, Liying He, Xueying Cai, Jiahui Lu, Di Wang*, Cordyceps militaris Fruit Body Extract ameliorates membranous glomerulonephritis by attenuating oxidative stress and renal inflammation via NF-kappa B pathway. Food & Function. 2016, 7: 2006-2015 (IF: 3.247) （1区）
38) Shuang Hu#, Di Wang#, Junrong Zhang, Mengyan Du, Yingkun Cheng, Yan Liu, Ning Zhang, Di Wang*, Yi Wu*. Mitochondria Related Pathway is Essential for Polysaccharides Purified from Sparassis Crispa Mediated Neuro-protection against Glutamate-induced Toxicity in Differentiated PC12 Cells. International Journal of Molecular Sciences. 2016, 17, 133; doi:10.3390/ijms17020133 (IF: 3.226) （2区）
39) Juan Wang, Jingjing Song, Di Wang, Na Zhang, Jiahui Lu, Qingfan Meng, Yulin Zhou, Ning Wang, Yang Liu, Di Wang*, Lesheng Teng*. The anti-membranous glomerulonephritic activity of purified polysaccharides from Irpex lacteus Fr.. International Journal of Biological Macromolecules, 2016, 84:87-93 (IF: 5.162) （1区）
40) Jingjing Song, Xintong Hou, Xinyu Hu, Chengyu Lu, Chunguang Liu, Juan Wang, Wei Liu, Lirong Teng, Di Wang*, Not only serotonergic system, but also Dopaminergic System Involved in Albiflorin against Chronic Unpredictable Mild Stress-Induced Depression-like Behavior in Rats. Chemico-Biological Interactions. 2015, 242:211-217. (IF: 3.143) （2区）
41) Jia Song, Jing Xie, Chenliang Li, Jiahui Lu, Qingfang Meng, Zhaogang Yang, Robert J. Lee, Di Wang*, Lesheng Teng*. Near Infrared Spectroscopic (NIRS) Analysis of Drug-Loading and Particle Size of Risperidone Microspheres by Improved Chemometric Model International Journal of Pharmaceutics. International Journal of Pharmaceutics, 2014, 472: 296-303 (IF: 3.65) （2区）