个人简历
吴玉清，女，博士、教授、博士生导师。1985-1989年在长春地质学院岩矿测试及分析系分析化学专业学习，获学士学位。1992-1998年在吉林大学理化所学习，先后获得硕士和博士学位，所学专业为物理化学。曾分别于1998、2000和2002年在日本关西学院大学理学部从事博士后和访问教授研究；并于2001年在法国里昂第一大学生物物理化学实验室进行访问教授研究。2001年10月始任吉林大学理论化学研究所教授，现工作于超分子结构与材料国家重点实验室。
研究领域
近年来主要从事生物体系分子识别、组装及相关机理研究，重点关注生物分子识别与组装过程中分子间的各种弱相互作用力、识别机理以及组装体功能，并注重发展多种相关谱学新方法。目前所开展的研究领域主要包括：(1) 病毒衣壳蛋白的体外组装调控和机理研究; (2) 骨疾病相关蛋白酶检测及靶向性药物研发；(3) 特异性纳米荧光探针的设计、合成及相关纳米生物技术及方法学研究。
近期论文
1. “Efficient Inhibition of HPV16 L1 Pentamer Formation by a Carboxylatopillarene and a p-Sulfonatocalixarene” Dong-Dong Zheng, Ding-Yi Fu, Yuqing Wu,* Yu-Long Sun, Li-li Tan, Ting Zhou, Shi-Qi Ma, Xiao Zha and Ying-Wei Yang* Chem. Commun. 2014, 50, 3201. 2. “The Critical Role of Helix 5 for in vitro Pentamer Formation and Stability of Papillomavirus Capsid Protein L1” Shi Jin, Dong Pan, Xiao Zha, Xianghui Yu, Yuqing Wu*, Yongjiang Liu, Ying Fei, Xiaojiang S. Chen* Mol. Biosystem. 2014, 10, 724. 3. “In Vitro Monitoring of the Formation of Pentamers from the Monomer of GST Fused HPV 16 L1”Dong-Dong Zheng, Dong Pan, Xiao Zha, Yuqing Wu,*Chunlai Jiang and Xianghui Yu*Chem. Commun. 2013, 49, 8546. 4. “The Nitril Based High Selective Inhibitors of Cathepsin K: Part II, Structural Optimization and Covalent Docking for Screening” Xiao-Yu Yuan, Jiao Liu, Xuexun Fang, Yuqing Wu,*Shu-XueZou, Lincong Wang, Org.Biomol.Chem. 2013, 11, 5847. 5. “Fluorescence-enhanced Sensing Mechanism of BSA-protected Small Gold-nanoclusters to Silver(I) Ions in Aqueous Solutions”Hong-Wei Li, Yuan Yue, Tian-Ying Liu, Dong-Mei Li, Yuqing Wu*J. Phys. Chem. C2013, 117, 16159. 6. “High Selective Azadipeptide Nitriles Inhibitors for Cathepsin K: Design, Synthesis and Activity Assay” Xing-Feng Ren, Hong-Wei Li, Xuexun Fang, Yuqing Wu,*Licong Wang, SuxueZouOrg.Biomol.Chem. 2013, 11, 1143. 7. “Pressure-induced Fluorescence Enhancement of AuNCs@BSA and the Conformational Changes of BSA” Min Zhang, Yong-Qiang Dang, Tian-Ying Liu, Hong-Wei Li, Yuqing Wu,*Qian Li; Kai Wang; Bo Zou* J. Phys. Chem. C 2013, 117, 639. 8. “Construction of a Supramolecular FRET System and Its Application Based on the Interaction between Cy3-Labeled Melittin and Phosphocholine Encapsulated Quantum Dots” Yong-Qiang Dang, Hong-Wei Li, Yuqing Wu* ACS Appl. Mater. Interfaces 2012, 4, 1267. 9. “The BSA-protected Small Gold-nanoclustersSynthezed by Microwave-assistence and their Fluorescence-Enhanced Sensing to Silver(Ι) Ions” Yuan Yue, Tian-Ying Liu, Hong-Wei Li*, Zhongying Liu, Yuqing Wu* Nanoscale 2012, 4, 2251. 10. “Fluorescence Visual Gel-separation of Dansyl-modified BSA-protected Gold-Nanoclusters”, Hong-Wei Li, Ke-Long Ai, Yuqing Wu* Chem. Commun. 2011, 47, 9852.
