刘雅文
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资料介绍
个人简历
讲授课程:流行病学预防医学临床流行病学现场调查技术教育经历:1986.09——1991.09白求恩医科大学预防医学院环境医学专业本科生,获得医学学士学位1991.09——1994.07白求恩医科大学预防医学院卫生毒理学专业研究生,获得医学硕士学位1999.09——2002.06吉林大学基础医学院生物化学与分子生物学专业研究生,获得理学博士学位工作经历:1994.07——1996.06白求恩医科大学预防医学院助教(1995.07)1996.06——2001.09白求恩医科大学预防医学院讲师2001.09——2006.09吉林大学公共卫生学院副教授2006.09——2012.12吉林大学公共卫生学院教授(2004.01——2008.01吉林大学基础医学流动站博士后)(2007.01——2008.01瑞典卡罗林斯卡大学公派访问学者)2012.12——现在吉林大学公共卫生学院副院长、教授研究领域
研究方向:分子遗传流行病学"科研项目:1.HDL偏低人群循环miRNA差异表达与原发性高血压关系的研究(81573230)国家自然科学基金2016-20192.胼胝体投射神经元发育机制的合作研究(编号2015DFA31580)科技部国家国际合作专项2015.4-2018.33.羟基脂肪酸类雌激素受体调节物对阿尔兹海默病作用机制研究(编号20150101130JC)科技厅自然科学基金2015.01-20174.他莫昔芬抗性乳腺癌治疗中DNA甲基化状态的修正策略研究(20140413016GH)科技厅国际合作2014-20165.ERβ通过负性调控XBP1对抗ERα阳性乳腺癌细胞增殖的机制研究(2013102009)白求恩B计划2014-20166.雌激素受体及NCOA1基因环境交互作用与2型糖尿病关系的研究(200905185)省科技厅2009-20117.雌激素受体辅助因子FOXP1调节基因表达分子机制研究教育部留学回国人员启动基金2009-20118.基因组中雌激素受体β与FOXA1的DNA结合位点解析及其对下游基因的调控作用(30870952)国家自然科学基金2009-20119.雌激素受体-转录辅助因子复合体对乳腺癌细胞基因的调制研究(20080735)省科技厅2009-201110.吉林省卫生人力资源发展状况调查研究(2001I003)省卫生厅2011.07-2012.0611.雌激素受体、RIP40基因与2型糖尿病易感性的关联研究(2001R009)省卫生厅2012.01-2014.12"近期论文
1.LiR1,LiW2,LunZ3,ZhangH4,SunZ5,KanuJS1,QiuS1,ChengY6,LiuY7.Prevalenceofmetabolicsyndromeinmainlandchina:ameta-analysisofpublishedstudies.BMCPublicHealth.2016Apr1;16(1):296.doi:10.1186/s12889-016-2870-y.2.Yu,MX(Yu,Mingxi)[1];Liu,YW(Liu,Yawen)[1];Li,Y(Li,Yong)[1];Zhang,HP(Zhang,Huiping)[2];Lu,YP(Lu,Yuping)[1];Kanui,JS(Kanui,JosephSam)[1];Qiao,YC(Qiao,Yichun)[1];Tang,Y(Tang,Yuan)[1];Zhen,Q(Zhen,Qing)[1];Cheng,Y(Cheng,Yi)[3]EndotheliallipasegenepolymorphismsareassociatedwithserumHDL-Clevelsbutnotcoronaryheartdisease.3.JosephSamKanu,YuluGu,SunZhi,MingxiYu,YupingLu,YetongCong,YunkaiLiu,YongLi,YaqinYu,YiCheng*andYawenLiu*.Singlenucleotidepolymorphismrs3774261intheAdipoQgeneisassociatedwiththeriskofcoronaryheartdisease(CHD)inNortheastHanChinesepopulation:acasecontrolstudy.LipidsHealthDis.2016Jan12;15(1):6.doi:10.1186/s12944-015-0173-4.4.XinZhang,YuluGu,XiaoliLiu,YaqinYu,JiepingShi,QiongYu,HuiSun,JosephSamKanu,SiyanZhan*,andYawenLiu*.AssociationofPre-miR-146ars2910164PolymorphismwithPapillaryThyroidCancer.IntJEndocrinol.2015;2015:802562.doi:10.1155/2015/802562.Epub2015Nov18.5.ZhijunLi,†,YanYao,†,YaqinYu,JiepingShi,YawenLiu,YuchunTao,ChangguiKou,HuipingZhang,WeiqingHan,YutianYin,LinglingJiangandBoLi*,PrevalenceandAssociatedFactorsofPassiveSmokingamongWomeninJilinProvince,China:ACross-SectionalStudy.IntJEnvironResPublicHealth.2015Oct30;12(11):13970-80.doi:10.3390/ijerph121113970.6.MingxiYu†,SiameGilbert†,YongLi,HuipingZhang,YichunQiao,YupingLu,YuanTang,QingZhen,YiCheng*,YawenLiu*.AssociationofNCOA3polymorphismswithDyslipidemiaintheChineseHanpopulation.LipidsHealthDis.2015Oct9;14:124.doi:10.1186/s12944-015-0126-y7.YupingLu,YawenLiu,YongLi,HuipingZhang,MingxiYu,JosephSamKanu,YichunQiao,YuanTang,QingZhen,YiCheng*.AssociationofATP-bindingcassettetransporterA1genepolymorphismswithplasmalipidvariabilityandcoronaryheartdiseaserisk.IntJClinExpPathol.2015Oct1;8(10):13441-9.eCollection2015.8.YupingLu#,TsadikGhebreamlakHabtetsion#,YongLi,HuipingZhang,YichunQiao,MingxiYu,YuanTang,QingZhen,YiCheng*,YawenLiu*.AssociationofNCOA2genepolymorphismswithobesityanddyslipidemiaintheChineseHanpopulation.IntJClinExpPathol.2015;8(6):7341-73499.ZhijunLi,YanYao,WeiqingHan,YaqinYu,YawenLiu,YuchunTao,ChangguiKou,LinglingJiang,QingSun,YutianYin,HuipingZhangandBoLi*.SmokingPrevalenceandAssociatedFactorsaswellasAttitudesandPerceptionstowardsTobaccoControlinNortheastChina.Int.J.Environ.Res.PublicHealth2015,12,8606-8618.10.DanLi,ZuojiaLiu,YeYuan,YawenLiu*.FenglanNiu*.Greensynthesisofgallicacid-coatedsilvernanoparticleswithhighantimicrobialactivityandlowcytotoxicitytonormalcells.ProcessBiochemistry.2015(50):357–366.11.FanWang#,YawenLiu#,YetongCong,PengpengLi,YongLi,ZhihuiYan,YuanTang,YiCheng,YangZheng.Shiftoftheinterconnectionfromthereactionsystemofparaoxonase1totheperoxidationreactionsystemofmyeloperoxidasewithHDL-Clevels:Amarkerofatherosclerosisinpatientswithnormalcholesterollevels.ClinicaChimicaActa.2015(438):350-370.12.Wang,S.,Kou,C.,Liu,Y.,Li,B.,Tao,Y.,D'Arcy,C.,Shi,J.,Wu,Y.,Liu,J.,Zhu,Y.,Yu,Y.Rural-UrbanDifferencesinthePrevalenceofChronicDiseaseinNortheastChina.Asia-PacificJournalofPublicHealth.2014.13.HuipingZhang,FanWang,HongqinXu,YawenLiu,JinLiu,HongyuZhao,JoelGelernter.Differentiallyco‑expressedgenesinpostmortemprefrontalcortexofindividualswithalcoholusedisorders:influenceonalcoholmetabolism‑relatedpathways.HumGenet.2014..14.ChangWang,YaqinYu,XiangyangZhang,YongLi,ChangguiKou,BoLi,YuchunTao,QingZhen,HuanHe,JosephSamKanu,XufengHuang,MeiHan,YawenLiu*.Awareness,treatment,controlofdiabetesmellitusandtheriskfactors:surveyresultsfromnortheastchina.PLoSOne.2014Jul28;9(7):e103594..15.YingCheng,HuiLi,LixiaMa,ShuangZhang,ShiYan,JingZhu,ShengWang,RuiZhang,KaiNiuandYawenLiu.Detectionofc-kitmutationalstatusinsmall-celllungcancerinaChinesecohort.ThoracicCancer.2014May;5(3):225–231.16.JosephSamKanu,YuanTang,YawenLiu*.AssessmentontheKnowledgeandReportedPracticesofWomenonMaternalandChildHealthinRuralSierraLeone:ACross-sectional.PLoSOne.2014Aug.28;9(8):e010593617.YuluGu,XiaoliLiu,YaqinYu,JiepingShi,LizheAi,HuiSun,JosephSamKanu,ChongWang,YawenLiu*.AssociationofATMgenepolymorphismwithPTCmetastasisinfemalepatients.InternationalJournalofEndocrinology.IntJEndocrinol.2014;2014:370825.doi:10.1155/2014/370825.Epub2014Oct16.18.JingWu,Dan-DanWang,Xin-LouLi,SakeJdeVlas,Ya-QinYu,JianZhu,YingZhang,BoWang,LiYan,Li-QunFang,Ya-WenLiu*,Wu-ChunCao.IncreasingincidenceofhemorrhagicfeverwithrenalsyndromecouldbeassociatedwithlivestockhusbandryinChangchun,northeasternChina.BMCInfectDis.2014,14(301)19.HuanHe,Ya-qinYu,YongLi,Chang-guiKou,BoLi,Yu-chunTao,QingZhen,ChangWang,JosephSamKanu,Xu-fengHuang,MeiHan,Ya-wenLiu*.Dyslipidemiaawareness,treatment,controlandinfluencefactorsamongadultsintheJilinprovinceinChina:across-sectionalstudy.LipidsHealthDis.2014,13(1):122.20.Gu,Yulu,Yu,Yaqin,Ai,Lizhe,Shi,Jieping,Liu,Xiaoli,Sun,Hui,Liu,Yawen*.AssociationoftheATMgenepolymorphismswithpapillarythyroidcancer.Endocrine.2014,45(3):454-461.21.Xu,Hongqin,Wang,Fan,Liu,Yawen,Yu,Yaqin,Gelernter,Joel,Zhang,Huiping.Sex-biasedmethylomeandtranscriptomeinhumanprefrontalcortex.HumanMolecularGenetics.2014,23(5):1260-1270.22.Zhao,Chunyan,Gao,Hui,Liu,Yawen,Papoutsi,Zoi,Jaffrey,Sadaf,Gustafsson,Jan-Ake,Dahlman-Wright,Karin.Genome-WideMappingofEstrogenReceptor-beta-BindingRegionsRevealsExtensiveCross-TalkwithTranscriptionFactorActivatorProtein-1.CancerResearch,2010,70(12):5174-5183.23.Liu,Yawen,Gao,Hui,Marstrand,TroelsTorben,Strom,Anders,Valen,Eivind,Sandelin,Albin,Gustafsson,Jan-Ake,Dahlman-Wright,Karin.ThegenomelandscapeofERalpha-andERbeta-bindingDNAregions.ProceedingsOfTheNationalAcademyOfSciencesOfTheUnitedStatesOfAmerica.2008,105(7):2604-2609.24.GaoPujun,ShiYang,GaoYanhang,LiuYawen,TanYan.Thereceptorforbeta(2)GPIonmembraneofhepatocellularcarcinomacelllineSMMC-7721isannexinII.WorldJGastroenterol.2007;13(24):3364-8.著作教材:预防医学吉林大学出版社2012副主编临床流行病学高等教育出版社2013编者流行病学基础复旦大学出版社2011编者流行病学协和医科大学出版社2017编者中国抗癌协会肿瘤流行病学专业委员会第七届常务委员吉林省预防医学会卫生应急分会第一届副主任委员吉林省预防医学会第六届卫生检验专业委员会常务委员吉林省预防医学会免疫规划专业委员会常务委员 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