个人简历

张坚， 男，教授，硕士生导师。研究方向为有机合成方法学、药物合成。博士毕业于新加坡南洋理工大学，师从著名有机化学家Teck-Peng Loh教授和Soon Hyeok Hong 教授；硕士毕业于南开大学，师从孙怀林教授；本科毕业于中南大学。2015年1月起到杭州师范大学工作（C类人才引进），2017年12月晋升为教授。2008年获得“天津市自然科学二等奖”（第二完成人）；入选2015年“西湖学者”，2017年市“131”人才；2019年，获得莱帕克-SNIC最佳墙报奖。近年来主持1项国家自然科学基金、2项浙江省自然科学基金等项目；已在惰性碳氢键官能化、不饱和烃选择性转化等研究领域获得了系列创新性成果，在Nat. Commun.、Angew. Chem. Int. Ed.、J. Am. Chem. Soc.、Org. Lett.、Chem. Commun. 等国际著名学术期刊上以第一作者或（和）通讯作者身份发表SCI一区论文20篇。担任Chem. Commun.、Org. Biomol. Chem.、Adv. Synth. Catal. 等国际知名化学期刊审稿人。近3年来，指导学生获得研究生国家奖学金2人次，浙江省大学生化学竞赛一等奖4次和二等奖5次，浙江省优秀毕业生2人次，国创项目和省“新苗计划”各1项等。

研究领域

"""""有机合成方法学、药物合成"

近期论文

K. Meng, T. Li, C. Yu, C. Shen, J. Zhang,* G. Zhong.* Geminal group-directed olefinic C-H functionalization via four- to eight-membered exo-metallocycles. Nat. Commun. 2019, DOI: doi.org/10.1038/s41467-019-13098-1. (IF 11.878, SCI 一区)\r
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C. Shen, X. Lu, J. Zhang,* L. Ding, Y. Sun, G. Zhong.* Bidentate auxiliary-directed alkenyl C-H allylation via exo-palladacycles: synthesis of branched 1,4-dienes. Chem. Commun., 2019, 55, 13582-13585. (IF 6.164, SCI 一区)\r
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L. Xu, K. Meng, J. Zhang,* Y. Sun, X. Lu, T. Li, Y. Jiang, G. Zhong,* Iridium-catalyzed alkenyl C–H allylation using conjugated dienes. Chem. Commun., 2019, 55, 9757-9760. (IF 6.164, SCI 一区)\r
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K. Meng, Y. Sun, J. Zhang,* K. Zhang, X. Ji, L. Ding, G. Zhong,* Iridium-Catalyzed Cross-Coupling Reactions of Alkenes by Hydrogen Transfer. Org. Lett. 2019, 21, 8219-8224. (IF 6.555, SCI 一区)\r
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T. Li, C. Shen, Y. Sun, J. Zhang,* P. Xiang, X. Lu, G. Zhong, Cobalt-Catalyzed Olefinic C−H Alkenylation/Alkylation Switched by Carbonyl Groups. Org. Lett. 2019, 21, 7772−7777. (IF 6.555, SCI 一区)\r
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Y. Sun, K. Meng, J. Zhang,* M. Jin, N. Huang, G. Zhong,* Additive- and Ligand-Free Cross-Coupling Reactions between Alkenes and Alkynes by Iridium Catalysis. Org. Lett. 2019, 21, 4868−4872. (IF 6.555, SCI 一区)\r
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X. Lu, C. Shen, K. Meng, L. Zhao,* T. Li, Y. Sun, J. Zhang,* G. Zhong,* Acylsilane directed aromatic C–H alkenylations by ruthenium catalysis. Chem. Commun., 2019, 55, 826-829. (IF 6.164, SCI 一区)\r
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C. Yu, F. Li, J. Zhang,* G. Zhong,* A direct cross-coupling reaction of electron-deficient alkenes using an oxidizing directing group. Chem. Commun., 2017, 53, 533. (IF 6.164, SCI 一区)\r
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T. Li, J. Zhang,* C. Yu, X. Lu, L. Xu, G. Zhong,* Ruthenium-catalyzed olefinic C–H alkenylation of enol-carbamates: highly stereo-selective synthesis of (Z,Z) and (Z,E)-butadienes Chem. Commun., 2017, 53, 12926-12929. (IF 6.164, SCI 一区)\r
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C. Yu, J. Zhang,* G. Zhong,* One step synthesis of c-alkylidenebutenolides from simple vinyl carboxylic acids and alkenes. Chem. Commun., 2017, 53, 9902. (IF 6.164, SCI 一区)\r
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K. Meng, J. Zhang,* F. Li, Z. Lin, K. Zhang, G. Zhong,* Amide Directed Cross-Coupling between Alkenes and Alkynes: A Regio- and Stereoselective Approach to Substituted (2Z,4Z)‑Dienamides. Org. Lett., 2017, 19, 2498. Highlighted in Synfacts 2017, 13, 721. (IF 6.555, SCI 一区)\r
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F. Li, C. Yu, J. Zhang,* G. Zhong,* Olefination of Electron-Deficient Alkenes with Allyl Acetate: Stereo-and Regioselective Access to (2Z,4E)‑Dienamides. Org. Lett., 2016, 18, 4582. (IF 6.555, SCI 一区)\r
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F. Li, C. Shen, J. Zhang,* L. Wu, L. Ding, G. Zhong,* Adv. Synth. Catal., 2016, 358, 3932. (IF 5.451, SCI 一区)\r
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Y. Chen, S. Wang, L. Zhao,* C. Rong, T. Liu, H. Sun, Y. Wang, J. Zhang,* G. Zhong,* A Metal-Free Synthesis of 3-Phenoxy Imidazo Heterocycles by Catalytic Oxidative Cyclization of 2-Amino-azaarenes with Lignin Models. Synthesis, 2018, 50, 3169-3176. (IF 2.867, SCI 三区)\r
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J. Zhang,* X. Lu, T. Li, S. Wang, G. Zhong,* Copper-Catalyzed Oxidative Cyclization of 2‑Amino-azaarenes with Lignin Models: Synthesis of 3‑Phenoxy Imidazo Heterocycles. J. Org. Chem., 2017, 82, 5222. (IF 4.745, SCI 二区)\r
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F. Li, C. Yu, J. Zhang,* G. Zhong,* Weinreb amide directed cross-coupling reaction between electron-deficient alkenes catalyzed by a rhodium catalyst. Org. Biomol. Chem., 2017, 15, 1236. (IF 3.490, SCI 三区)\r
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L. Ding, C. Yu, Z. Zhao, F. Li, J. Zhang,* G. Zhong,* Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate. J. Vis. Exp., 2017, 124, 55766. ( SCI 四区)