个人简历

1979-1983年，兰州大学生物系动物学专业，本科生\r
1983-1986年，湖南师范大学生物系发育生物学专业，硕士研究生\r
1987-1992年，美国爱荷华大学生物学系，博士研究生\r
1992-1997年，美国旧金山加州大学，神经发育学专业，博士后\r
1997-2001年，美国路易斯威尔大学解剖科学与神经生物学系，助理教授\r
2001-2004年，美国路易斯威尔大学解剖科学与神经生物学系，终身职副教授\r
2004-至今，美国路易斯威尔大学解剖科学与神经生物学系，终身职正教授\r
2009-至今，杭州师范大学生命与环境科学学院，教授\r
2014-至今，杭州师范大学生命科学研究院，院长

研究领域

""一、胶质细胞发育及相关疾病研究\r
1.神经胶质细胞产生与发育过程中的分子途径和信号通路\r
2.转录因子在髓鞘形成和维持过程中的功能研究\r
3.脑肿瘤产生及治疗的分子机制研究\r
\r
二、神经损伤与再生修复研究\r
1.脊髓损伤后的分子细胞变化及调控机理研究\r
2.干细胞移植再生修复的探索：运用发育关键调控分子促使神经干细胞或多功能干细胞（iPS）定向诱导分化成特定的神经元或神经胶质细胞，从而进行神经环路和髓鞘的再生修复。\r
3.星状胶质细胞重编码研究：运用最新体细胞重编码技术使星状胶质细胞原位转化为特定神经元或少突胶质细胞，促进神经环路和髓鞘的再生修复""""

近期论文

1. Zhu Q, Zhao X, Zheng K, Li H., Huang H., Zhang Z., Wegner M, Chen Y., Sussel L and Qiu M*. (2014). Genetic evidence that Nkx2.2 and PDGFRα are major determinants of the timing of oligodendrocyte differentiation in the developing CNS. Development.141(3):548-55.\r
\r
2. Li X., Liu Z., Qiu M. and Yang Z. (2014). Cross-repressive interactions between Sp8 and Nkx2.2 specify the identity of pMN and p3 progenitors in the spinal cord. Development. 141(14):2875-84.\r
\r
3. Zhou L, Shao C, Xu S, Xie Y, Zhou L, Teng P, Wang Y, Qiu M* and Shen Y*. (2014) GSK3β promotes the differentiation of oligodendrocyte precursor cells via β-catenin-mediated transcriptional regulation. Mol. Neurobiol. 50(2):507-19. (*co-corresponding author)\r
\r
4. Dai Z., Sun S, Wang C, Hao H, Hu X, Zhang Z, Lu QR, Qiu M*. (2014). Stage-specific regulation of oligodendrocyte development by Wnt/β-catenin signaling. J. Neurosci. 34(25):8467-73.\r
\r
5. Zhao X, Huang H, Teng P, Zhu Q, Zheng K, Hu X , Xie B, Sander M and Qiu M*. (2014). Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor.PlosOne 9(10):e109171.\r
\r
6. Liu Z, Hu X, Huang C, Zheng K, Takebayashi H, Cao C and Qiu M*. (2014). OLIG3 is not involved in the ventral patterning of spinal cord. PlosOne 9(10):e111076.\r
\r
7. Sun S., Guo W., Zhang Z., Qiu M* and Dai Z* . (2015). Dosage-dependent regulation of oligodendrocyte specification by β-catenin signaling. Neuroscience Bulletin.31(2):271-3\r
\r
8. Liu W, Zhou H, Liu L, Zhao C, Deng Y, Chen L, Wu L, Mandrycky N, McNabb CT, Peng Y, Fuchs PN, Lu J, Sheen V, Qiu M, Mao M, Richard Lu Q. (2015). Disruption of neurogenesis and cortical development in transgenic mice misexpressing Olig2, a gene in the Down syndrome critical region. Neurobiol Dis. 77:106-116.\r
\r
9. Liu Y, Wang M., Zhao W, Yuan X, Yang X., Li Y, Qiu M, Zhu X, Zhang Z. （2015）Gpr177-Mediated Wnt Signaling is required for Secondary Palate Development . J Dent Res. 94(7):961-7.\r
\r
10. Chen Y, Mei R, Teng P, Yang A, Hu X, Zhang Z, Qiu M*, Zhao X*. (2015). TAPP1 inhibits the differentiation of oligodendrocyte precursor cells via suppressing the Mek/Erk pathway. Neurosci Bull.31(5):517-26. (Co-corresponding author)\r
\r
11. Zhu Q, Tan Z, Zhao X, Hu X., Huang H., Zhang Y., Shields C., and Qiu M*. (2015). Developmental expression and functional analysis of PTPRD in axonal myelination. Neuroscience 308:106-114\r
\r
12. Zhou L., Huang H., Qiu M., Shen Y. (2015). Numb deficiency in cerebellar Purkinje cells impairs surface expression of metabotropic glutamate receptor and motor coordination. PNAS. 112(50):15474-9.\r
\r
13. Li X., Chi Q, Chen Y., Xu X., Hu X, Zhang Z, Qiu M*. Zheng K. (2016) miRNAs regulates the terminal differentiation of astrocytes in the developing CNS. Neuroscience. 312:99-107. (*Co-corresponding author)\r
\r
14. Zhu X-J, Sun S, Xie B, Hu X, Zhang Z, Qiu M*, and Dai Z-M* (2016). Guanine-rich sequences inhibit proofreading DNA polymerases. Sci Rep. 6:28769.\r
\r
15. Yang J, Zhang X, Wu Y, Zhao B , Liu X, Pan Y, Ding Y, Qiu M, Wang Y-Z , Zhao G. (2016). Wnt/β-catenin signaling mediates the seizure-facilitating effect of post-ischemic reactive astrocytes after pentylenetetrazole-kindling. Glia, 64, 1083-91.\r
\r
16. Yang J, Liu X, Zhang X, Zhao X, Pan Y, Qiu M, Wu S, Zhao G, Wang YZ. (2016). Predominant neuronal differentiation of Olig1+ neural progenitors in forebrain cortex biased by β-catenin over-expression. Neurosci Lett. 622, 19-23.\r
\r
17. Yang J, Cheng X,Shen J, Xie B, Zhao X, Zhang Z, Cao Q-L,Shen Y and Qiu M*. (2016). A novel approach for amplification and purification of mouse oligodendrocyte progenitor cells. Front. Cell. Neurosci. 10:203.\r
\r
18. Xu X., Liu Z., Hu X., Zhang Z. and Qiu M*. (2017). AP-2α and AP-2β regulate dorsal interneuron specification in the spinal cord. Neuroscience,340:232-242.\r
\r
19. Huang H, Teng P, Mei R, Yang A, Zhang Z, Zhao X*, Qiu M*. (2017). Tmeff2 is expressed in differentiating oligodendrocytes but dispensable for their differentiation in vivo. Sci Rep, 7(1):337.\r
\r
20. Cheng X, Xie B, Zhao X, Zunyi Zhang, Qiu M*, Yang J*. (2017). Rat astrocytes are more supportive for mouse OPC self-renewal than mouse astrocytes in culture. Dev. Neurobiol, 77(8):907-916.