个人简历

教育经历
09/2003-07/2007 中国农业大学，生物科学，学士
09/2003-07/2007 中国农业大学，工商管理（生物技术企业经营管理），学士
09/2007-06/2013 北京生命科学研究所，生物化学与分子生物学，博士
07/2013-03/2015 北京生命科学研究所，博士后
工作经历
01/2014-02/2017 十堰市太和医院，感染与免疫性疾病研究所所长，中心实验室主任，副教授，硕导
03/2017-至今 华中农业大学，教授，博导

研究领域

病原微生物与宿主互作，感染与免疫分子机制，死亡受体信号通路调节，新型蛋白质翻译后修饰

近期论文

1. Luo J, Hu J, Zhang Y, Hu Q andLi S#. (2015) Hijacking of death receptor signaling by bacterial pathogen effectors.Apoptosis20:216-223.(Corresponding author)
2. Pan M*,Li S*,Li X, Shao F, Liu L, and Hu H. (2014) Synthesis and Specific Antibody generation of Glycopeptides with ArginineN-GlcNAcylation.Angewandte Chemie International Edition53（52）：14517-14521.(Co-first author)
3.Li S*, Zhang L*, Yao Q, Li L, Dong N, Rong J, Gao W, Ding X, Sun L, Chen X, Chen S†, Shao F†. (2013) Pathogen blocks host death receptor signaling by arginine GlcNAcylation of death domains.Nature.501, 242-246.（First author）This work was featured inNature Reviews Microbiology
4. Lu Q,Li S, and Shao F. (2015) Sweet talk: protein glycosylation in bacterial interaction with the host.Trends in microbiology23(10):630-641.
5. Lu Q, Yao Q, Xu Y, Li L,Li S, Liu Y, Gao W, Niu M, Sharon M, Ben-Nissan G, Zamyatina A, Liu X, Chen S, Shao F (2014) An iron-containing dodecameric heptosyltransferase family modifies bacterial autotransporters in pathogenesis.Cell host & microbe16 (3):351-363.
6. Li C, Tu S, Wen S,Li S, Chang J, Shao F, Lei X.(2011) Total Synthesis of the G2/M DNA Damage Checkpoint Inhibitor Psilostachyin C.The Journal of Organic Chemistry, 76, 3566-70.
7. Cui J, Yao Q,Li S, Ding X, Lu Q, Mao H, Liu L, Zheng N, Chen S, Shao F. (2010) Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family.Science, 329, 1215-8.
8. Gong YN, Wang X, Wang J, Yang Z,Li S, Yang J, Liu L, Lei X, Shao F. (2010) Chemical probing reveals insights into the signaling mechanism of inflammasome activation.Cell Research, 20, 1289-305.
9. Ge J, Xu H, Li T, Zhou Y, Zhang Z,Li S, Liu L, Shao F.(2009)ALegionellatype IV effector activates the NF-κB pathway by phosphorylating the IκB family of inhibitors.Proc. Natl. Acad. Sci., 106, 13725-30.
10. Wei B, Cai T, Zhang R, Li A, Huo N,Li S, Gu YQ, Vogel J, Jia J, Qi Y, Mao L.(2009) Novel microRNAs uncovered by deep sequencing of small RNA transcriptomes in bread wheat (Triticum aestivum L.) and Brachypodium distachyon (L.) Beauv.Funct Integr Genomics., 9, 499-511.
11. Mi S, Cai T, Hu Y, Chen Y, Hodges E, Ni F, Wu L,Li S, Zhou H, Long C, Chen S, Hannon G, Qi Y. (2008) Sorting of small RNAs intoArabidopsisArgonaute complexes is directed by the 5’ terminal nucleotide.Cell, 133: 116-127. This work was featured inCell133:25-26, 2008.
12. Zhao T, Li G, Mi S,Li S, Hannon G, Wang XJ*, Qi Y.* (2007). A complex system of small RNAs in the unicellular green algaChlamydomonas reinhardtii.Genes and Development,29, 1190-1203. This work was featured in:Cell129:1029, 2007;Genes and Development21: 1153-1156, 2007;Nature447: 5, 2007;Nature447: 518, 2007;Nature Review Genetics8: 406, 2007;ACS Chemical Biology2: 436-437, 2007.