个人简历

教育经历
2005.9 - 2010.7，四川大学，化学生物学，博士（硕博连读）
2001.9 - 2005.7，华中师范大学，化学系，学士
主要职历
2014.7 - 至今， 华中农业大学信息学院，副教授
2013.9 - 2014.6 华中农业大学理学院，副教授
2011.7 - 2013.7 美国堪萨斯大学 博士后
2010.10 - 2011.7 美国俄克拉荷马 博士后

研究领域

生物信息学、化学信息学和系统生物学

近期论文

1. Le Zhan, Hui-Xin Liu, Yaping Fang, Bo Kong, Yuqi He, Xiao-bo Zhong, Jianwen Fang, Yu-Jui Yvonne Wan, Grace L. Guo*. Genome-Wide Binding and Transcriptome Analysis of Human Farnesoid X Receptor in Primary Human Hepatocytes. PLoS ONE, 2014, 9(9):e105930
2. Yaping Fang†, Shan Gao†, David Tai, C Russell Middaugh and Jianwen Fang*. Identification of properties important to protein aggregation using feature selection. BMC Bioinformatics, 2013, 14:314 (†Co-first author)
3. Yuqi He, Lei Gong, Yaping Fang, Qi Zhan, Huixin Liu, Yanliu Lu, Grace L. Guo, Lois Lehman-McKeeman, Jianwen Fang, and Yu-Jui Yvonne Wan*. The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling., BMC Genomics, 2013,28;14(1):575
4. Hui-Xin Liu, Yaping Fang, Ying Hu, Frank J Gonzalez, Jianwen Fang and Yu-Jui Yvonne Wan*. PPARβ Regulates Liver Regeneration by Modulating E2f Signaling. PLoS ONE, 2013, 8(6): e65644
5. Shu-Lin Wang, Yaping Fang, and Jianwen Fang*. Diagnostic Prediction of Complex Diseases Using Phase-Only Correlation Based on Virtual Sample Template, BMC Bioinformatics, 2013, 14(S8):S11
6. Ann M. Thomas, Steve N. Hart, Guodong Li, Hong Lu, Yaping Fang, Jianwen Fang, Xiao-bo Zhong, Grace L. Guo*. Hepatocyte Nuclear Factor 4 Alpha and Farnesoid X Receptor Co-regulates Gene Transcription in Mouse Livers on a Genome-wide Scale. Pharm Res. 2013, 30(9):2188-2198
7. Ying Hu, Hui-Xin Liu, Yuqi He, Yaping Fang, Jianwen Fang, and Yu-Jui Yvonne Wan*. Transcriptome profiling and genome-wide DNA binding define the differential role of fenretinide and all-trans RA in regulating the death and survival of human Huh7 cells.Biochemical Pharmacology, 2013, 85(7):1007-1017
8. Yaping Fang and Jianwen Fang*. Discrimination of soluble and aggregation-prone proteins based on sequence information, Mol. BioSyst., 2013, 9(4):806-811.
9. Yaping Fang, Hui-xin Liu, Ning Zhang, Grace L. Guo, Yu-Jui Yvonne Wan, Jianwen Fang*. NURBS: A Database of Experimental and Predicted Nuclear Receptor Binding Sites of Mouse, Bioinformatics, 2013, 29(2), 295-297
10. Yaping Fang, C. Russell Middaugh and Jianwen Fang*. In silico classification of proteins from acidic and neutral cytoplasms, PLoS ONE, 2012, 7(9): e45585.
11. Yaping Fang, Jun Li*. Genomic law guided gene prediction in fungi and metazoans, Int. J. of Computational Biology and Drug Design (IJCBDD), 2013, 6, 157-169
12. Qi Zhan, Yaping Fang, Yuqi He, Huixin Liu, Lei Gong, Lois Lehman-McKeeman, Jianwen Fang, and Yu-Jui Yvonne Wan*. Function annotation of hepatic retinoid x receptor alpha based on genome-wide DNA binding and transcriptome profiling, PLoS ONE, 2012, 7(11): e50013.
13. Shan Gao, Shuo Xu, Yaping Fang and Jianwen Fang*. Prediction of core cancer genes using multitask classification framework. J. Theor. Biol., 2012, 317:62-70 (IF:2.208)
14. Shan Gao, Shuo Xu, Yaping Fang, Jianwen Fang*. Investigating kinase-specific phosphorylation sites using multitask learning methods, Proteome Science. 2012, 10(S1):S7.
15. Cuicui Wang†, Yaping Fang†, Menglong Li*, Jiamin Xiao. Identification RNA-binding sites in proteins by integrating various sequence information, Amino Acids, 2011, 40, 239-48 (†Co-first author)
16. Yunqi Li, Yaping Fang, Jianwen Fang*. Predicting residue-residue contacts using random forest models, Bioinformatics, 2011, 27, 3379-3384
17. Yaping Fang, Daichuan Ma, Menglong Li*, Zhining Wen, Yuanbo Diao. Investigation of the proteins folding rates and their properties of Amino Acid Networks, Chemom Intell Lab Syst. 2010, 101, 123-129
18. Lirong Liu, Yaping Fang, Menglong Li*, Cuicui Wang. Prediction of Beta-Turn in Protein Using E-SSpred and Support Vector Machine, Protein J, 2009, 28, 175-181
19. Jiang Wu, Yuanbo Diao, Menglong Li*, Yaping Fang, Daichuan Ma. A semi-supervised learning based method: Laplacian support vector machine used in diabetes disease diagnosis, Interdiscip Sci Comput Life Sci, 2009, 1, 151-155
20. Yaping Fang, Yanzhi Guo, Yi Feng, Menglong Li*. Predicting DNA-binding proteins: approached from Chou’s pseudo amino acid composition and other specific sequence features, Amino Acids, 2008, 34,103-109
21. Yaping Fang, Yi Feng, Menglong Li*. Optimal QSAR analysis of the carcinogenic activity of aromatic and heteroaromatic amine, QSAR Comb Sci, 2008, 27, 543-554