个人简历

教育经历
2001.09－2004.06， 天津大学， 理学院， 博士研究生
1996.09－1999.06， 青岛化工学院， 化工系， 硕士研究生
1991.09－1995.06， 青岛化工学院， 化工系， 本科
主要职历
2014.07－至今， 华中农业大学信息学院， 教授 、博士生导师
2009.02－2014.06， 华中农业大学生命科学技术学院， 教授 、博士生导师
1999.07－2009.02， 山东理工大学生命科学学院， 历任讲师、副教授
1995.07－1996.08， 山东滨州印染集团公司， 质检员

研究领域

植物及微生物基因组、转录组分析；代谢及蛋白互作网络构建及分析

近期论文

1.Sun J, Liu H, Liu J, Cheng S, Peng Y, Zhang Q, Yan J, Liu HJ*,Chen LL*.CRISPR-Local: a local single-guide RNA (sgRNA) design tool for non-reference plant genomes.Bioinformatics, bty970,https://doi.org/10.1093/bioinformatics/bty970
2.Song JM, Lei Y, Shu CC, Ding Y, Xing F, Liu H, Wang J, Xie W, Zhang J,Chen LL*. Rice Information GateWay: a comprehensive boinformatics platform for indica rice genomes.Mol Plant, 2018, 11(3):505-507.
3.Liu H, Ding Y, Zhou Y, Jin W, Xie K*,Chen LL*.CRISPR-P 2.0: an improved CRISPR-Cas9 tool for genome editing in plants.Mol Plant, 2017, 10(3):530-532.
4.Zhang J#,Chen LL#, Sun S, et al. Building two indica rice reference genomes with PacBio long-read and Illumina paired-end sequencing data.Sci Data, 2016, 3:160076.#Co-firstauthors.
5.Zhang J#,Chen LL#, Xing F#, et al. Extensive sequence divergence between the reference genomes of two elite indica rice varieties Zhenshan 97 and Minghui 63.ProcNatl Acad Sci U S A, 2016, 113(35): E5163-71.#Co-firstauthors.
6.Ding Y, Li H,Chen LL*, Xie K*. Recent advances in genome editing using CRISPR/Cas9.Front Plant Sci., 2016, 7:703.
7.Guo J, Zhang H, Wang C, Chang JW,Chen LL*. Construction and analysis of a genome-scale metabolic network forBacillus licheniformisWX-02.Res Microbiol., 2016, 167(4): 282-9.
8.Guo J, Cheng G, Gou XY, Xing F, Li S, Han YC, Wang L, Song JM, Shu CC, Chen SW*,Chen LL*. Comprehensive transcriptome and improved genome annotation ofBacillus licheniformisWX-02.FEBS Lett., 2015, 589(18): 2372-81.
9.Wang C, Deng ZL, Xie ZM, Chu XY, Chang JW, Kong DX, Li BJ, Zhang HY,Chen LL*. Construction of a genome-scale metabolic network of the plant pathogenPectobacterium carotovorumprovides new strategies for bactericide discovery.FEBS Lett., 2015, 589(3): 285-94.
10.Chen D, Fu LY, Zhang Z, Li G, Zhang H, Jiang L, Harrison AP, Shanahan HP, Klukas C, Zhang HY, Ruan Y*,Chen LL*, Chen M*. Dissecting the chromatin interactome of microRNA genes.Nucleic Acids Res.,2014, 42(5): 3028-43.
11.Ding YD, Chang JW, Guo J, Chen D, Li S, Xu Q, Deng XX, Cheng YJ,Chen LL*. Prediction and functional analysis of the sweet orange protein-protein interaction network.BMC Plant Biol.,2014, 14(1): 213.
12.Lei Y, Lu L, Liu HY, Li S, Xing F,Chen LL*. CRISPR-P: A Web Tool for Synthetic Single-Guide RNA Design of CRISPR-System in Plants.Mol Plant,2014, 7(9): 1494-1496.
13.Guo FB, Lin Y,Chen LL*. Recognition of protein-coding genes based on Z-curve algorithms.Current Genomics, 2014, 15:95-103.
14.Xu Q#,Chen LL#, Ruan X#, et al. The draft genome of sweet orange (Citrus sinensis).Nature Genetics, 2013, 45: 59-66.#Co-firstauthors.
15.Jiao WB, Huang D, Xing F, HuY, Deng XX, Xu Q*,Chen LL*. Genome-wide characterization and expression analysis of genetic variants in sweet orange.Plant J., 2013, 75: 954-964.
16.Chen D, Yuan C, Zhang J, Zhang Z, Bai L, Meng Y,Chen LL*, Chen M*. PlantNATsDB: a comprehensive database of plant natural antisense transcripts.Nucleic Acids Res., 2012, 40: D1187-1193.