个人简历

华中科技大学同济药学院、国家纳米药物工程技术研究中心教授，博士生导师，药剂学系主任。2003-2007年新加坡国立大学博士、博士后，2007-2010年美国哈佛大学医学院博士后。2010年至今在华中科技大学任教授、博士生导师。

研究领域

研究方向为药物递送系统联合肿瘤免疫治疗：1) 基于维生素E TPGS的新型纳米药物抑制肿瘤多药耐药性研究；2）基于仿生药物递送系统的肿瘤免疫联合治疗研究

近期论文

[27] Conglian Yang#, Tingting Wu#, Yan Qi1, Zhiping Zhang*. Recent Advances in the Application of Vitamin E TPGS for Drug Delivery. Theranostics 2018; 8(2):464-485. [26] Yongdan Zhao, Qingle Song, Yijia Yin, Tingting Wu, Xiaomeng Hu, Xueqin Gao, Gao Li, Songwei Tan, Zhiping Zhang*. Immunochemotherapy mediated by thermosponge nanoparticles for synergistic anti-tumor effects. Journal of Controlled Release 2017, 269: 322-326. [25] Tingting Wu, Yan Qi, Dan Zhang, Qingle Song, Conglian Yang, Xiaomeng Hu, Yuling Bao, Yongdan Zhao, and Zhiping Zhang*. Bone Marrow Dendritic Cells Derived Microvesicles for Combinational Immunochemotherapy against Tumor. Adv Funct Mater 2017, 27, 1703191. [24] Kong M, Tang J, Qiao Q, Wu T, Qi Y, Tan S, Gao X, Zhang Z*. Biodegradable Hollow Mesoporous Silica Nanoparticles for Regulating Tumor Microenvironment and Enhancing Antitumor Efficiency. Theranostics 2017, 7(13): 3276-3292. [23] Xie J, Yang C, Liu Q, Li J, Liang R, Shen C, Zhang Y, Wang K, Liu L, Shezad K, Sullivan M, Xu Y, Shen G, Tao J*, Zhu J*, Zhang Z*. Encapsulation of Hydrophilic and Hydrophobic Peptides into Hollow Mesoporous Silica Nanoparticles for Enhancement of Antitumor Immune Response. Small 2017, 13: 1701741. [22] Song Q, Yin Y, Shang L, Wu T, Zhang D, Kong M, Zhao Y, He Y, Tan S*, Guo Y, Zhang Z*. Tumor Microenvironment Responsive Nanogel for the Combinatorial Antitumor Effect of Chemotherapy and Immunotherapy. Nano Lett 2017, 17(10): 6366-6375. [21] Yin M#, Tan S#, Bao Y, Zhang Z*. Enhanced tumor therapy via drug co-delivery and in situ vascular-promoting strategy. J Control Release 2017, 258: 108-120. [20] Xiaomeng Hu, Tingting Wu, Yuling Bao, Zhiping Zhang*. Nanotechnology based therapeutic modality to boost anti-tumor immunity and collapse tumor defense. Journal of Controlled Release 2017, 256: 26-45. [19] Mingxing Yin, Yuling Bao, Xueqin Gao, Yupei Wu, Yu Sun, Xinyuan Zhao, Hongzhe Xu, Zhiping Zhang* and Songwei Tan*. Redox/pH dual-sensitive hybrid micelles for targeting delivery and overcoming multidrug resistance of cancer. Journal of Materials Chemistry B 2017, 5: 2964-2978. [18] Yuling Bao, Mingxing Yin, Xiaomeng Hu, Xiangting Zhuang, Yu Sun, Yuanyuan Guo, Songwei Tan*, Zhiping Zhang*. A safe, simple and efficient doxorubicin prodrug hybrid micelle for overcoming tumor multidrug resistance and targeting delivery. Journal of Controlled Release 2016, 235:182-194. [17] Xiangting Zhuang, Tingting Wu, Yongdan Zhao, Xiaomeng Hu, Yuling Bao, Yuanyuan Guo, Qingle Song, Gao Li, Songwei Tan, Zhiping Zhang*, Lipid-Enveloped Zinc Phosphate Hybrid Nanoparticles for Codelivery of H-2Kb and H-2Db-Restricted Antigenic Peptides and Monophosphoryl Lipid A to Induce Antitumor Immunity against Melanoma. Journal of Controlled Release 2016, 228: 26–37. [16] Yuanyuan Guo, Boning Niu, Qingle Song, Yongdan Zhao, Yuling Bao, Songwei Tan, Luqin Si*, and Zhiping Zhang*, RGD-Decorated Redox-Responsive D-α-Tocopherol Polyethylene Glycol Succinate-Poly(lactide) Nanoparticles for Targeted Drug Delivery. Journal of Materials Chemistry B 2016, 4: 2338-2350. [15] Yuanyuan Guo#, Dong Wang#, Qingle Song, Tingting Wu, Xiangting Zhuang, Yuling Bao, Miao Kong, Yan Qi, Songwei Tan, and Zhiping Zhang*, Erythrocyte Membrane-Enveloped Polymeric Nanoparticles as Nano-vaccine for Induction of Antitumor Immunity against Melanoma, ACS Nano, 2015, 9(7): 6918-6933. [14] Songwei Tan, Tingting Wu, Dan Zhang, Zhiping Zhang*. Cell or cell membrane-based drug delivery systems. Theranostics 2015, 5(8): 863-881. [13] Xu Li, Cuixia Gao, Yupei Wu, C-Yan Cheng, Weiliang Xia and Zhiping Zhang*. Combination delivery of Adjudin and Doxorubicin via integrating drug conjugation and nanocarrier approaches for the treatment of drug resistant cancer cells. Journal of Materials Chemistry B 2015, 3: 1556-1564. [12] Yupei Wu#, Qian Chu#, Songwei Tan, Xiangting Zhuang, Yuling Bao, Tingting Wu, Zhiping Zhang*, D-α-tocopherol Polyethylene Glycol Succinate-Based Derivative Nanoparticles as a Novel Carrier for Paclitaxel Delivery, International Journal of Nanomedicine, 2015, 10: 5219-5235. [11] Tan SW#, Sasada T#, Bershteyn A, Yang KY, Ioji T, Zhang ZP*. Combinational delivery of lipid-enveloped polymeric nanoparticles carrying different peptides for anti-tumor immunotherapy. Nanomedicine 2014, 9(5): 635-647. [10] Qingle Song, Songwei Tan, Xiangting Zhuang, Yuanyuan Guo, Yongdan Zhao, Tingting Wu, Qi Ye, Luqin Si*, and Zhiping Zhang*. Nitric oxide releasing d-α-tocopheryl polyethylene glycol succinate for enhancing antitumor activity of doxorubicin. Molecular Pharmaceutics 2014, 11(11): 4118-4129. [9] Yuling Bao#, Yuanyuan Guo#, Xiangting Zhuang, Dan Li, Bolin Cheng, Songwei Tan*, Zhiping Zhang*. D-α-tocopherol polyethylene glycol succinate based redox-sensitive paclitaxel prodrug for overcoming multidrug resistance in cancer cells. Molecular Pharmaceutics 2014, 11(9): 3196-3209. [8] Guo YY#, Chu M#, Tan SW, Zhao S, Liu HX, Otieno BO, Yang XL, Xu CR*, ZhangZP*. Chitosan-g-TPGS nanoparticles for anticancer drug delivery and overcoming multidrug resistance. Molecular Pharmaceutics 2014, 11(1): 59-70.