个人简历

工作经历 2016.12 至今副教授，华中科技大学同济药学院，博士生导师 2013.09-2016.12博士后 助理研究员，中国农业科学院蔬菜花卉研究所 合作导师 黄三文 研究员 2011.08-2013.09项目主管，扬子江药业集团中药研究院 教育背景 2008.09-2011.07博士，北京大学药学院 导师 屠鹏飞 教授 2005.09-2008.07硕士，大连大学环境与化学工程学院 导师 王永奇 教授 2001.09-2005.07学士，衡阳师范学院化学与材料科学系

研究领域

1.天然活性次生代谢产物的功能基因及合成生物学研究 2.中药及天然药物的物质基础及作用机制研究

近期论文

1. Yang Zhong#, Xiaofeng Xue#, Zhiqiang Liu#, Yongshuo Ma, Kewu Zeng, Lida Han, Dae-Kyun Ro, Sanwen Huang, Yuan Zhou*, Yi Shang*. Developmentally regulated glucosylation of bitter triterpenoid in cucumber by the UDP-glucosyltransferase UGT73AM3. Molecular Plant. 2017, 10, 1000-1003 2. Yuan Zhou#, Yongshuo Ma#, Jiangguo Zeng#, Lixin Duan#, Xiaofeng Xue, Huaisong Wang, …, Pengfei Tu, Zhonghua Zhang, Anne Osbourn, Dae-Kyun Ro, Yi Shang*, Sanwen Huang*. Convergence and divergence of bitterness biosynthesis and regulation in cucumber, melon and watermelon. Nature Plants, 2016, 2, 16183. 3. Yongsuo Ma#, Yuan Zhou#, Sergey Ovchinnikov, Per Jr Greisen, Sanwen Huang, Yi Shang*. New insights into substrate folding preference of plant OSCs. Science Bulletin, 2016, 61, 1407-1414. 4. Yi Shang#, Yongshuo Ma#, Yuan Zhou#, Huimin Zhang#, Lixin Duan, Huiming Chen, Jianguo Zeng, …, William J. Lucas, Sanwen Huang*. Biosynthesis, regulation, and domestication of bitterness in cucumber. Science, 2014, 346, 1084-1088. 5. Yuan Zhou, Kewu Zeng, Jiayu Zhang, Ning Li, Xingyun Chai, Yong Jiang, Pengfei Tu*. Triterpene saponins from the roots of Ilex pubescens
. Fitoterapia, 2014, 97, 98-104. 6. Yuan Zhou, Ning Li, Jiayu Zhang, Yong Jiang, Pengfei Tu*. Simultaneous determination of four triterpenoid saponins and two liganoids in the roots of Ilex pubescens by RP­HPLC­DAD. Journal of Chinese Pharmaceutical Sciences, 2014, 23, 866-872. 7. Zhixing Qing#, Yuan Zhou#, Xiubin Liu, Pi Cheng, Jianguo Zeng*. 23, 24-Dihydrocucurbitacin C: a new compound regarded as the next metabolite of cucurbitacin C. Natural Product Research, 2014, 28, 1165-1170. 8. Lu Zheng#, Yuan Zhou#, Jiayu Zhang, Min Song, Ye Yuan, Yanjiao Xiao, Ting Xiang*. Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis. Chinese Journal of Natural Medicine, 2014, 12, 142-147. 9. Yuan Zhou, Xingyun Chai, Kewu Zeng, Jiayu Zhang, Ning Li, Yong Jiang, Pengfei Tu*. Ilexpublesnins C–M, Eleven New Triterpene Saponins from the Roots of Ilex pubescens. Planta Medica, 2013, 79, 70-77. 10. Yuan Zhou, Baomin Feng*, Liying Shi, Huiguo Wang, Ling Tang and Yongqi Wang. Two new 3-oxo-α-ionol glucosides from Urtica laetevirens Maxim. Natural Product Research, 2011, 25, 1219-1223. 11. Yuan Zhou, Wei Wang, Ling Tang, Xingguo Yan, Liying Shi, Yongqi Wang, Baomin Feng*. Lignan and flavonoid glycosides from Urtica laetevirens Maxim. Journal of Natural Medicines, 2009, 63, 100-101. 12. Jiayu Zhang#, Wei Cai#, Yuan Zhou, Ying Liu, Xiaodan Wu, Yun Li, Jianqiu Lu, Yanjiang Qiao*. Profiling and identification of the metabolites of baicalin and study on their tissue distribution in rats by ultra-high-performance liquid chromatography with linear ion trap-Orbitrap mass spectrometer. Journal of Chromatography B, 2015, 985, 91-102. 13. Ning Li, Liang Zhang, Kewu Zeng, Yuan Zhou, Jiayu Zhang, Yanyun Che, Pengfei Tu*. Cytotoxic steroidal saponins from Ophiopogon japonicas. Steroids 2013, 78, 1-7. 14. Jiayu Zhang, Ning Li, Yuan Zhou, Yong Jiang and Pengfei Tu*. Simultaneous qualitative and quantitative determination of major polymethoxylated flavonoids in the leaves of Murraya paniculata by RRLC-DAD-ESI-MSn. Analytical Methods, 2012, 4, 3399-3406. 15. Wei Wang, Xingguo Yan, Lixin Duan, Yuan Zhou, Ling Tang, Yongqi Wang, Baomin Feng*. Two new secolignans from the roots of Urtica mairei Levl. Chinese Chemical Letter, 2008, 19, 1212-1214.