个人简历

1995.09 ~ 1999.07武汉大学化学系应用化学专业，获应用化学理学学士学位； 2002.09 ~ 2007.06武汉大学化学系硕博连读，获分析化学理学博士学位； 2007.07 ~ 2009.06华中科技大学同济医学院药学院从事博士后研究； 2009.07 ~迄今 华中科技大学同济医学院药学院从事教学和科学研究； 2011.10~2012.10加拿大滑铁卢大学访问学者。

研究领域

主要从事新型固相萃取材料的制备和微型化固相萃取装置的设计，并实现上述萃取材料和萃取装置在环境、食品以及生物样品中的痕量/超痕量药物的分析研究；中药/天然产物活性成分的分离与分析、体内药物分析、中药指纹图谱分析和药物质量评价等。

近期论文

[1] Wei, Han; Wu, Guanghua; Chen, Jinglou; Zhang, Xuenong;Xiong, Chaomei; Lei, Yongfang; Chen, Wei; Ruan, Jinlan, (2S)-5, 2', 5'-Trihydroxy-7-Methoxyflavanone, a Natural Product from Abacopteris penangiana, Presents Neuroprotective Effects In Vitro and In Vivo, Neurochemical Research,AUG 2013, 38(8), 1686-1694 [2] Yang, Aixia; Wang, Xiaoxian;Xiong, Chaomei; Chen, Jing; Ruan, Jinlan, Quality control of tuirejieduling granules using high-performance liquid chromatography fingerprint method and simultaneous determination of four main active ingredients, Pharmacognosy Magazine, APR-JUN 2013, 9(34): 162-166 [3] Chen, Jing;Xiong, Chao-Mei; Song, Shan-Shan; Han, Pan; Ruan, Jin-Lan,Fraction of Macroporous Resin from Smilax china L. Inhibits Testosterone Propionate-Induced Prostatic Hyperplasia in Castrated Rats, Journal of Medicinal Food,JUL 2012, 15(7): 646-650 [4] Yuan, Qianying; Cai, Shaoxin; Zhang, Xuenong; Liu, Ziwei; Li, Zhaoming; Luo, Xuelai;Xiong, Chaomei; Wang, Jianping; Hu, Junbo; Ruan, Jinlan. A new protoapigenone analog RY10-4 induces apoptosis and suppresses invasion through the PI3K/Akt pathway in human breast cancer.Cancer Letters (New York, NY, United States) (2012), 324(2), 210-220. [5] Wei, Anhua; Zhou, Daonian; Ruan, Jinlan; Cai, Yaling;Xiong, Chaomei; Wu, Guanghua. Anti-tumor and anti-angiogenic effects of Macrothelypteris viridifrons and its constituents by HPLC-DAD/MS analysis. Journal of Ethnopharmacology (2012), 139(2), 373-380. [6] Liu, Huibin; Jiang, Chunyang;Xiong, Chaomei; Ruan, Jinlan. DEDC, a new flavonoid induces apoptosis via a ROS-dependent mechanism in human neuroblastoma SH-SY5Y cells. Toxicology In Vitro, (2012), 26(1), 16-23. [7] Wu Guanghua; Cai Yaling; Wei Han; Wei Anhua;Xiong Chaomei; Fu Wei; Ruan Jinlan. Nephroprotective activity of Macrothelypteris oligophlebia rhizomes ethanol extract. Pharmaceutical biology (2012), 50(6), 773-7. [8] Ruan, Jinlan; Yuan, Qianying;Xiong, Chaomei; Liu, Ziwei.Preparation of 2-(1-hydroxy-4-oxo-2,5-cyclohexadien-1-yl)-4H-pyran-4-one as antitumor agent.Faming Zhuanli Shenqing (2012),CN 102731456 A 20121017. [9] Chen, Jinglou; Lei, Yongfang; Wu, Guanghua; Zhang, Yonghui; Fu, Wei;Xiong, Chaomei; Ruan, Jinlan. Renoprotective potential of Macrothelypteris torresiana via ameliorating oxidative stress and proinflammatory cytokines. Journal of Ethnopharmacology (2012), 139(1), 207-213. [10]Liu, Ziwei; Yuan, Qianying; Zhang, Xuenong;Xiong, Chaomei; Xue, Pingping; Ruan, Jinlan. RY10-4, a novel anti-tumor compound, exhibited its anti-angiogenesis activity by down-regulation of the HIF-1α and inhibition phosphorylation of AKT and mTOR. Cancer Chemotherapy and Pharmacology (2012), 69(6), 1633-1640. [11]HB Liu, YL Xiao,CM Xiong, AH Wei, JL Ruan. Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation,European Journal of Pharmacology, 2011, 654(3): 209–216. [12]YF Lei, W Fu, JL Chen,CM Xiong, GH Wu, H Wei, JLRuan.Neuroprotective effects of Abacopterin E fromAbacopteris penangianaagainst oxidative stress-induced neurotoxicity,Journal of Ethnopharmacology, 2011, 134(2): 275-280. [13]YF Lei, JL Chen, YL Cai,CM Xiong, JL Ruan. Hypolipidemic potential ofLepidogrammitis drymoglossoidesin high-fat diet fed mice,International Journal of Cardiology, 2011, 147(2), 323–325. [14]JL Chen, YF Lei, YJ Liu,CM Xiong, W Fu,JL Ruan, Extract ofCyclosorus acuminatusattenuates diabetic nephropathy in miceviamodifying peroxisome proliferators activated receptor signalling pathway, Food Chemistry, 2011, 128(3): 659-666. [15]Y Tang,CM Xiong, DN Zhou, AH Wei, W Fu, YL Cai, JL Ruan. A new flavonoid fromMacrothelypteris torresiana. Chemistry of Natural Compounds,2010, 46(2): 209–211. [16]XH Huang, PC Xiong,CM Xiong, YL Cai, AH Wei, JP Wang, XF Liang, JL Ruan.In vitro and in vivo antitumor activity ofMacrothelypteris torresianaand its acute/subacute oral toxicity,Phytomedicine, 2010, 17(12): 930–934. [17]W Fu, YF Lei, JL Chen,CM Xiong, DN Zhou, GH Wu, J Chen, YL Cai, JL Ruan. Parathelypteriside attenuates cognition deficits in D-galactose treated miceby increasing antioxidant capacity and improving long-term potentiation,Neurobiology of Learning and Memory,2010, 94(3): 414–421. [18]CM Xiong, YC Qin, B Hu.On-line separation/preconcentration of V(IV)/V(V) in environmental water samples with CTAB-modified alkyl silica microcolumn and their determination by inductively coupled plasma-optical emission spectrometry,Journal of Hazardous Materials, 2010, 178(1-3): 164–170. [19]CM Xiong, B Hu. Headspace trapping of the hydrides on a Pd (II)-coated graphite adsorptive bar as a microextraction method for ETV-ICP-MS determination of Se, Te and Bi in seawater and human hair samples,Talanta, 2010, 81(1-2): 578–585. [20]DN Zhou, JL Ruan, YL Cai,CM Xiong, W Fu, AH Wei. Antioxidant and hepatoprotective activity of ethanol extractArachniodes exilis(Hance) Ching,Journal of Ethnopharmacology, 2010, 129(2): 232–237.