个人简历

教育背景 2012. 9－2017. 7 理学博士 北京大学 化学与分子工程学院 2008. 9－2012. 7 理学学士 北京大学 化学与分子工程学院 2009. 9－2012. 7 经济学学士（双学位） 北京大学 国家发展研究院 工作经历 2017. 8－2018. 10 博士后 加拿大阿尔伯塔大学 病理与实验医学系 2018.10至今 副教授，华中科技大学 同济医学院药学院

研究领域

""主要研究兴趣为疾病相关生物标志物的检测及其在精准医疗、药效评价等方面的应用。""""

近期论文

1. Tongbo Wu, Yufei Yang, Wei Chen, Jiayu Wang, Ziyu Yang, Shenlin Wang, Xianjin Xiao, Mengyuan Li and Meiping Zhao*, Noncanonical substrate preference of lambda exonuclease for 5’-nonphosphate-ended dsDNA and a mismatch-induced acceleration effect on the enzymatic reaction, Nucleic Acids Research, 2018, 46, 3119-3129. (IF=11.561) 2. Tongbo Wu, Wei Chen, Ziyu Yang, Haocheng Tan, Jiayu Wang, Xianjin Xiao, Mengyuan Li and Meiping Zhao*, DNA terminal structure-mediated enzymatic reaction for ultra-sensitive discrimination of single nucleotide variations in circulating cell-free DNA, Nucleic Acids Research, 2018, 46, e24. (IF=11.561) 3. Tongbo Wu, Xianjin Xiao, Zhe Zhang and Meiping Zhao*, Enzyme-mediated single-nucleotide variation detection at room temperature with high discrimination factor, Chemical Science, 2015, 6, 1206–1211. (IF=9.063) 4. Tongbo Wu, Xianjin Xiao, Feidan Gu and Meiping Zhao*, Sensitive discrimination of stable mismatched base pairs by abasic site modified fluorescent probe and lambda exonuclease, Chemical Communications, 2015, 51, 17402–17405. (IF=6.290) 5. Xuzhe Zhang†, Tongbo Wu†, Hongbo Wang, Yufan Zou, Wei Chen, Meiping Zhao, Shanshan Wang* and Xianjin Xiao*, A time-dependent fluorescent biosensor for uracil-DNA glycosylase detection based on the uracil inhibition effect towards archaebacterial DNA polymerases, Sensors and Actuators B: Chemical, 2018, 270, 277-282. (IF=5.667) 6. Tongbo Wu, Yuan Liang, Xiaocui Zhu, Meiping Zhao* and Huwei Liu, Separation and quantification of four isomers of indole-3-acetyl-myo-inositol in plant tissues using high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry, Analytical and Bioanalytical Chemistry, 2014, 406, 3239–3247. (IF=3.307)