个人简历

工作经历:\r
2014 副院长 华中科技大学同济药学院\r
2012 教授 华中科技大学同济药学院\r
2007-2011 研究科学家 美国安进制药, 药物化学部\r
2004-2007 博士后 美国哥伦比亚大学，斯隆-凯特林癌症研究中心 Prof. Samuel J. Danishefsky \r
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教育经历: \r
2007 “药品生产质量管理规范”课程 美国斯隆-凯特林癌症研究中心 \r
2000-2004理学博士 法国巴黎第11大学分子与材料化学学院 Prof. André Lubineau 和 Prof. Marie-Christine Scherrmann \r
1999-2000 理学硕士 法国巴黎第十一大学分子与材料化学学院 Prof. Claudine Augé \r
1997-1999 硕士研究生 华中师范大学化学系\r
1993-1997 理学学士 华中师范大学化学系

研究领域

"""""具有自主知识产权的新药开发\r
新的糖化学的合成方法和策略发展\r
具有生物活性有机小分子的设计与合成\r
自由基化学及水相有机反应\r
以糖化合物为基础的抗癌疫苗的研制(设计

近期论文

One-pot Relay Glycosylation Xiong Xiao, Jing Zeng, Jing Fang, Jiuchang Sun, Ting Li, Zejin Song, Lei Cai and Qian Wan*J. Am. Chem. Soc., 2020, 142, 5498. DOI: 10.1021/jacs.0c00447\r
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Application of Interrupted Pummerer Reaction Mediated (IPRm) Glycosylation in Natural Product Synthesis Xiang Zhao, Jing Zeng, Lingkui Meng and Qian Wan*Chem. Rec., 2020, xx, xx. DOI: 10.1002/tcr.201900097\r
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Water Compatible Hypophosphites-d2 Reagents: Deuteration Reaction via Deutero-deiodination in Aqueous Solution Zejin Song, Jing Zeng, Ting Li, Xiang Zhao, Jing Fang, Lingkui Meng and Qian Wan*Org. Lett., 2020, 22, 1736. DOI: 10.1021/acs.orglett.0c00001\r
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Dehydrative Glycosylation Enabled by a Comproportionation Reaction of 2-Aryl-1,3-Dithiane 1-Oxide Lei Cai, Jing Zeng, Ting Li, Ying Xiao, Xiang Ma, Xiong Xiao, Qin Zhang, Lingkui Meng, Qian Wan*Chin. J. Chem., 2020, 38, 43-49. DOI: 10.1002/cjoc.201900419\r
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Glycosylation Enabled by Successive Rhodium(II) and Brønsted Acid Catalysis Lingkui Meng, Peng Wu, Jing Fang, Ying Xiao, Xiong Xiao, Guangsheng Tu, Xiang Ma, Shuang Teng, Jing Zeng, Qian Wan*J. Am. Chem. Soc., 2019, 141, 11775. DOI: 10.1021/jacs.9b04619\r
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Total Syntheses of Resin Glycosides Murucoidins IV and V Jing Fang, Jing Zeng, Jiuchang Sun, Shuxin Zhang, Xiong Xiao, Zimin Lu, Lingkui Meng, Qian Wan*Org. Lett., 2019, 21, 6213. DOI: 10.1021/acs.orglett.9b02004\r
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Hydrogen-Bonding-Assisted Exogenous Nucleophilic Reagent Effect for β-Selective Glycosylation of Rare 3-Amino Sugars Jing Zeng*, Ruobin Wang, Shuxin Zhang, Jing Fang, Shanshan Liu, Guangfei Sun, Bingbing Xu, Ying Xiao, Dengxian Fu, Wenqi Zhang, Yixin Hu, and Qian Wan*J. Am. Chem. Soc., 2019, 141, 8509. DOI: 10.1021/jacs.9b01862\r
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Advances on Photo-Promoted Glycosylation Reactions Hao Wang, Pinru Wu, Xiang Zhao, Jing Zeng, Qian Wan*Acta Chim. Sinica 2019, 77, 231, DOI: 10.6023/A18100429\r
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Calcium hypophosphite mediated deiodination in water: mechanistic insights and applications in large scale syntheses of D-quinovose and D-rhamnose Zejin Song, Lingkui Meng, Ying Xiao, Xiang Zhao, Jing Fang, Jing Zeng, Qian Wan*Green Chem., 2019, 21, 1122, DOI: 10.1039/c8gc03851a\r
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Collective syntheses of phenylethanoid glycosides by interrupted Pummerer reaction mediated glycosylations Yueqi Zhao, Jing Zeng, Yan Liu, Xiong Xiao, Guangfei Sun, Jiuchang Sun, Penghua Shu, Dengxian Fu, Lingkui Meng, Qian Wan*J. Carbohydr. Chem. , 2018, 37, 471. DOI: 10.1080/07328303.2018.1541997\r
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Mechanism investigations of the activation process of S-2-[(propan-2-yl)sulfinyl]benzyl (SPSB) glycosides Wei Chen, Jing Zeng, Zhiwen Liao, Shuang Teng, Xiong Xiao, Lingkui Meng, Qian Wan*J. Carbohydr. Chem. , 2018, 37, 498. DOI: 10.1080/07328303.2018.1541998\r
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Diversified Synthesis and alfa-Selective Glycosylation of 3- Amino-2,3,6-trideoxy Sugars Jing Zeng,* Ruobin Wang, Wang Yao, Shuxin Zhang, Guangfei Sun, Zhiwen Liao, Lingkui Meng, Qian Wan*Org. Chem. Front., 2018, 5, 3391 DOI: 10.1039/C8QO00948A\r
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Practical Synthesis of Active O-2-(2-Propylsulfinyl)benzyl (OPSB) Glycosides via a Catalytic and Metal Free Oxidation of Latent O-2-(2-Propylthiol)benzyl (OPTB) Glycosides Ying Xiao, Zimin Lu, Xiang Zhao, Pinru Wu, Wei Chen, Ruobin Wang, Jing Zeng, Qian Wan*Carbohydr. Res, 2018, 469, 10. DOI: 10.1016/j.carres.2018.08.014\r
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Glycosyl Sulfoxides in Glycosylation Reactions Jing Zeng, Yan Liu, Wei Chen, Xiang Zhao, Lingkui Meng, Qian Wan*Top. Curr. Chem. (Z), 2018, 376, 27. DOI:10.1007/s41061-018-0205-4\r
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1,4-Dithiothreitol Mediated Cleavage of the Acetal and Ketal Type of Diol Protecting Groups Yan Liu, Jing Zeng, Jiuchang Sun, Lei Cai, Yueqi Zhao, Jing Fang, Bo Hu, Penghua Shu, Lingkui Meng and Qian Wan* Org. Chem. Front., 2018, 5, 2427. DOI: 10.1039/C8QO00247A\r
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Interrupted Pummerer Reaction in Latent/Active Glycosylation Lingkui Meng, Jing Zeng, Qian Wan*Synlett 2018, 29, 148. DOI: 10.1055/s-0036-1588582\r
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Gold-Catalyzed Diversified Synthesis of 3-Aminosugar Analogues of Digitoxin and Digoxin Jing Zeng *, Guangfei Sun, Ruobin Wang, Shuxin Zhang, Shuang Teng, Zhiwen Liao, Lingkui Meng, Qian Wan*Org. Chem. Front., 2017, 4, 2450. DOI: 10.1039/c7qo00648a\r
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Practical Synthesis of Latent Disarmed S-2-(2-propylthio) Benzyl Glycosides for Interrupted Pummerer Reaction Mediated Glycosylation Yang Xu, Qian Zhang, Ying Xiao, Pinru Wu, Wei Chen, Zejin Song, Xiong Xiao, Linkui Meng, Jing Zeng, Qian Wan* Tetrahedron Lett, 2017, 58, 2381. DOI: 10.1016/j.tetlet.2017.05.014\r
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3-Aminodeoxypyranoses in Glycosylation: Diversity-Oriented Synthesis and Assembly in Oligosaccharides Jing Zeng*, Guangfei Sun, Yangbin Zhu, Ruobin Wang, Lei Cai, Ke Liu, Qian Zhang, Xuewei Liu, Qian Wan* Angew. Chem. Int. Ed., 2017, 56 , 5227. DOI: 10.1002/anie.201700178\r
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Remote Activation of Disarmed Thioglycosides in Latent-Active Glycosylation via Interrupted Pummerer Reaction Xiong Xiao, Yueqi Zhao, Penghua Shu, Xiang Zhao, Yan Liu, Jiuchang Sun, Qian Zhang, Jing Zeng, and Qian Wan*J. Am. Chem. Soc. 2016, 138, 13402. DOI: 10.1021/jacs.6b08305