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刘亚妮
2023-05-11 03:30
  • 刘亚妮
  • 刘亚妮 - 副教授 硕士生导师-华中科技大学-同济医学院-个人资料

近期热点

资料介绍

个人简历


2006年华中科技大学同济医学院药学院硕士毕业,于附属协和医院药学部实验室工作至今。

研究领域


药物代谢动力学;免疫抑制剂精准治疗临床实践研究;遗传药理学

近期论文


1. Tolerability and pharmacokinetics of hydronidone, an antifibrotic agent for hepatic fibrosis, after single and multiple doses in healthy subjects: an open-label, randomized, dose-escalating, first-in-human study. Eur J Drug Metab Pharmacokinet. 2017; 42(1):37-48. 2. Association of RAC1 gene polymorphisms with primary end-stage renal disease in chinese renal recipients. PLoS One. 2016; 11(2): e0148270. 3. Identification and association of RAC1 gene polymorphisms with mRNA and protein expression levels of Rac1 in solid organ (kidney, liver, heart) transplant recipients. Mol Med Rep. 2016;14(2):1379-1388. 4. Impact of quercetin‑induced changes in drug‑metabolizing enzyme and transporter expression on the pharmacokinetics of cyclosporine in rats. Mol Med Rep. 2016;14(4):3073-3085. 5. Tolerability and pharmacokinetics of disodium folinate following single intravenous doses in healthy Chinese subjects: an open-label, randomized, single-center study. Eur J Drug Metab Pharmacokinet. 2015; 40(4):443-451. 6. Tolerability, pharmacokinetics, and pharmacodynamics of recombinant human parathyroid hormone (1-34) in healthy chinese subjects. Clin Ther. 2014; 36(6):940-952 7. Tolerability and pharmacokinetics of biapenem following single and multiple intravenous administrations in healthy chinese subjects: an open-label, randomized, single-center study. Drug Res (Stuttg). 2013; 63(8): 396–403. 8. Safety, tolerability, pharmacokinetics and pharmacodynamics of recombinant human parathyroid hormone [rhpth(1-84)] after single- and multiple-dose subcutaneous administration in healthy chinese volunteers. Basic Clin Pharmacol Toxicol. 2012; 110(2): 154-161. 9. A simple and sensitive liquid chromatographic technique for the determination of cefotetan disodium in human plasma and its application in a pharmacokinetic study. J Huazhong Univ Sci Technolog Med Sci. 2012; 32(5):779-784. 10. Pharmacokinetics, pharmacodynamics, and tolerability of a generic formulation of exenatide: a randomized, open-label, single- and multiple-dose study in healthy Chinese volunteers. Arzneimittelforschung. 2012; 62(2): 75-82. 11. Pharmacokinetics and tolerability of intravenous cefotetan disodium for injection in healthy chinese volunteers: a randomized, open-label, single- and multiple-dose study. Clin Ther. 2010; 32(10):1832-1841. 12. Comparative bioavailability and tolerability of a single 20-mg dose of two fluoxetine hydrochloride dispersible tablet formulations in healthy fasting chinese male volunteers: an open-label, randomized-sequence, two-period crossover study. Clin Ther. 2010; 32(11):1977-1986.

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