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姜宏梁
2023-05-11 03:29
  • 姜宏梁
  • 姜宏梁 - 教授 博士生导师-华中科技大学-同济医学院-个人资料

近期热点

资料介绍

个人简历


教育背景 2001/08-2005/07 美国亚利桑那大学药学博士 1998/09-2001/07 北京协和医学院 生药学 硕士 1994/09-1998/07 沈阳药科大学 中药制药专业 学士 工作经历 2011/04-现在华中科技大学 药物分析与代谢 教授、博导 2010/11-2011/04 美国Covance Inc.公司药物分析与药代动力学 资深研究员 2006/12-2010/11 美国Covance Inc. 公司 药物分析与药代动力学 研究员 2005/08-2006/11 美国西北太平洋国家实验室 生物分析博士后

研究领域


药物分析和代谢、中药药代动力学及代谢组学。

近期论文


1.Meiling Huang, Zhongzhe Cheng, Lu Wang, Yulin Feng, Jiangeng Huang, Zhifeng Du, Hongliang Jiang*, A targeted strategy to identify untargeted metabolites from in vitro to in vivo: Rapid and sensitive metabolites profiling of licorice in rats using ultra-high performance liqud chromatography coupled with triple quadrupole-linear ion trap mass spectrometry, Journal of Chromatography B, 2018, 1092:40-50. 2.Yingfei Yan, Zhifeng Du, Hongliang Jiang*, HRMS for the quantification of xenobiotics in biological samples, Bioanalysis, 2017, 9(24), 1939-1941. 3.Sen Li, Shuna Jin, Chengwu Song, Shuailong Jia, Yang Zhang, Yulin Feng, Zhifeng Du*, Hongliang Jiang*, The strategy for establishemeng of the multiple reaction monitoring based characteristic chemical profile of triterpenes in Alismatis rhizoma using two combined tandem mass spectrometers, Journal of Chromatography A, 2017, 1524, 121-134. 4. Shuailong Jia, Zhifeng Du, Chengwu Song, Shuna Jin, Yang Zhang, Yulin Feng, Chaomei Xiong, Hongliang Jiang*, Identification and characterization of curcuminoids in turmeric using ultra-high performance liquid chromagraphy-quadrupole time of flight tandem mass spectrometry, Jounal of Chromatography A, 2017, 1521, 110-122. 5. Liang Liu, Xing Zhou, Tingting Wu, Hongliang Jiang, Sitao Yang, Yang Zhang, Dose optimisation of voriconazole with therapeutic drug monitoring in children: a single-centre experience in China, International Journal of Antimicrobial Agents, 2017, 49, 483-487. 6.Guiying Chen#,Chengwu Song#, ShunaJin, Sen Li, Yang Zhang, Rongzeng Huang, Yulin Feng, Yong Xu, Yi Xiang,Hongliang Jiang*, An integrated strategy for establishment of metabolite profile of endogenous lysoglycerophospholipids by two LC-MS/MS platforms, Talanta, 2017, 162, 530-539. 7. ShunaJin#, Chengwu Song#, ShuailongJia, Sen Li, Yang Zhang, Cheng Chen, Yulin Feng, Yong Xu, ChaomeiXiong, Yi Xiang, Hongliang Jiang*, An integrated strategy for establishment of curcuminoid profile in turmeric using two LC-MS/MS platforms, Journal of Pharmaceutical and Biomedical Analysis, 2017, 132, 93-102. 8. Zhongzhe Cheng, Xing Zhou, Bingying Hu, Wenyi Li, Guiying Chen, Yang Zhang, Jingkui Tian, Lin Zhang, Ming Li*, Hongliang Jiang*, Tissue distribution of capilliposide B, capilliposide C and their bioactive metabolite in mice using liquid chromatography-tandem mass spectrometry, Biomedical Chromatography, 2016, doi:10.1002/bmc.3895. 9.Chang Chen, Ariane Wohlfarth, Hui Xu, Dan Su, Xin Wang, Hongliang Jiang, Yulin Feng, Mingshe Zhu, Untargeted screening of unknown xenobiotics and potential toxins in plasma of poisoned patients using high-resolution mass spectrometry: Generation of xenobiotic fingerprint using background subtraction, AnalyticaChimicaActa, 2016, 944, 37-43. 10.Chang Chen, Bingying Hu, Tongzhi Wu, Yang Zhang, Yong Xu, Yulin Feng, Hongliang Jiang*, Bile acid profiles in diabetic (db/db) mice and their wild type littermates, Journal of Pharmaceutical and Biomedical Analysis, 2016, 131, 473-481. 11.Zhongzhe Cheng, Xing Zhou, Wenyi Li, Bingying Hu, Yang Zhang, Yong Xu, Lin Zhang*, Hongliang Jiang*, Optimization of solid-phase extraction and liquid chromatography-tandem mass spectrometry for simultaneous determination of capilliposide B and its active metabolite in rat urine and feces: overcoming nonspecific binding, Journal of Pharmaceutical and Biomedical Analysis, 2016, 131, 6-12. 12.Guiying Chen, Zhongzhe Cheng, Kerong Zhang, Hongliang Jiang*, Mingshe Zhu*, An integrated approach for profiling oxidative metabolites and glutathione adducts using liquid chromatography coupled with ultraviolet detection and triple quadrupole-linear ion trap mass spectrometry, Journal of Pharmaceutical and Biomedical Analysis, 2016, 129, 482-491. 13.Xin Zhou, Chang Chen, Fangrong Zhang, Yang Zhang, Yulin Feng, Hui Ouyang, Yong Xu, Hongliang Jiang*, Metabolism and bioactivation of the tricyclic antidepressant amitriptyline in human liver microsomes and human urine, Bioanalysis, 2016, 8(13), 1365-1381. 14.Xin Zhou, Fangrong Zhang, Chang Chen, ZitaoGuo, Jia Liu, Jinghua Yu, Yong Xu, DafangZhong*, Hongliang Jiang*, Impact of curcumin on the pharmacokinetics of rosuvastatin in rats and dogs based on the conjugated metabolites, Xenobiotica, 2016, 47(3),267-275. 15.Chengwu Song, Qingsong Yu, Xiaohua Li, ShunaJin, Sen Li, Yang Zhang, ShuailongJia, Cheng Chen, Yi Xiang, Hongliang Jiang*, The hypolipidemic effect mice and its composition characterized by UPLC-QTOF-MS/MS, Journal of Food Science, 2016, 81(5), 1313-1319. 16.Guangjie Yang, Fangrong Zhang, Linfang Deng, Chang Chen, Zhongzhe Cheng, Jiangeng Huang, Jiangyun Liu*, Hongliang Jiang*, Development and validation of an LC-MS/MS method for simultaneous quantification of levodopa and MD01 in rat plasma and its application to a pharmacokinetic study of mucunapruriens extract, Biomedical Chromatography, 2016, 30(9), 1506-1514. 17.Zhongzhe Cheng, Meilin Huang, Guiying Chen, Guangjie Yang, Xin Zhou, Chang Chen, Yang Zhang, Yong Xu, Yulin Feng, Lin Zhang*, Hongliang Jiang*, Cell-based assays in combination with ultra-high performance liquid chromatography-quadrupole time of flight tandem mass spectrometry for screening bioactive Capilliposide C metabolites generated by rat intestinal microflora, Journal of Pharmaceutical and Biomedical Analysis, 2016, 119, 130-138.

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