曹慧芬
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资料介绍
个人简历
教育经历:2011/09-2016/12,北京师范大学,生命科学学院,博士,导师:林魁教授 2007/08-2011/06,兰州大学,数学与统计学院,学士基金项目:目前主持在研的基金项目包括:国家自然科学青年科学基金(24万)、厦门市青年创新项目(15万)、福建省面上项目(4万)和华侨大学校级启动项目(8万元)各一项。参与在研项目包括:国家自然科学基金面上项目(58万)和福建省面上项目(5万)各一项。专著:1. E. Pang, H. Cao, B. Zhang, K. Lin,2015, Crop Genome Annotation: The Brassica rapa Genome. In: Xiaowu Wang, Chittaranjan Kole, The Brassica rapa Genome,Springer, New York. p. 53–63.专利:1. 一种检测全基因组的单链DNA损伤的方法,CN201810561048.8,中国(排名第二)。2. 一种检测DNA中单链断裂的方法,CN201910837092.1,中国(排名第二)。研究领域
功能基因组学;DNA损伤;抗癌药物的作用机制。""近期论文
1. Cao H, Salazar-García L, Gao F, Wahlestedt T, Wu CL, Han X, Cai Y, Xu D, Wang F, Tang L, Ricciardi N, Cai D, Wang H, Chin MPS, Timmons JA, Wahlestedt C, Kapranov P. Novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells. Nat Commun. 2019 Dec 20;10(1):5799.(Nature子刊,IF 12)2. Cao H, Claes W, Pillip K. (2018) Strategies to Annotate and Characterize Long Noncoding RNAs: Advantages and Pitfalls. Trends Genet 34:704-721. (Cell 子刊,IF 11)3. Liu Xiu#, Liu Y#, Huang P#, Ma Y#, Qing Z#, Tang Q#, Cao H#, Lin K, Ro D, Chen X, Xiong X, Shang Y*, Huang S*, and Zeng L*, The genome of the medicinal plant Macleaya cordata provides new insights into benzylisoquinoline alkaloids metabolism. Mol Plant. 2017;10(7):975-989.(共同第一作者,SCI 一区,IF 12)4. Cao H, Pang E, Lin K. Hierarchical Map of Orthologous Genomic Regions Reconstructed from Two Closely Related Genomes: Cucumber Case Study. Plant Geno. 2016 Nov;9(3). 5. Xu D, Cai Y, Tang L, Han X, Gao F, Cao H, Qi F, Kapranov P. A CRISPR/Cas13-based approach demonstrates biological relevance of vlinc class of long non-coding RNAs in anticancer drug response. Sci Rep. 2020 Feb 4;10(1):1794.6. Lai Y, Yeung CKL, Omland K, Pang E, Hao Y, Liao B, Cao H, Zhang B, Yeh C, Hung C, Hung H, Yang M, Liang W, Hsu Y, Yao C, Dong L, Lin K, Li S. Standing genetic variation as the predominant source for adaptation of a songbird. PNAS. 2019 Feb 5;116(6):2152-2157. (SCI 一区,IF 9)7. Lin K, Limpens E, Zhang Z, Ivanov S, Saunders DG, Mu D, Pang E, Cao H, Cha H, Lin T, Zhou Q, Shang Y, Li Y, Sharma T, van Velzen R, de Ruijter N, Aanen DK, Win J, Kamoun S, Bisseling T, Geurts R, Huang S. Single nucleus genome sequencing reveals high similarity among nuclei of an endomycorrhizal fungus. PLoS Genet. 2014 Jan;10(1):e1004078.8. Huang BH, Pang E, Chen YW, Cao H, Ruan Y, Liao PC. Positive selection and functional divergence of R2R3-MYB paralogous genes expressed in inflorescence buds of Scutellaria species (Labiatae). Int J Mol Sci. 2015 Mar 13;16(3):5900-21. 相关热点
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