个人简历

2014年毕业于北京大学生命科学院，获得细胞生物学理学博士学位。2016年于北京大学深圳研究生院做博士后，后在北京大学深圳研究生院任Co-PI。2020年9月入职华南师范大学脑科学与康复医学研究院，青年英才，特聘研究员。主要研究方向：1）基因编辑工具的开发与应用；2）斑马鱼疾病模型（缺血性疾病）的构建与病理机制研究。3）斑马鱼胰腺的发育与再生。目前已经在Cell research, Nature communications, Bmc biology, Cell death and disease等期刊发表一作（含共一）或通讯作者（含共通讯）SCI论文10篇，累计引用率过百。先后获得了国家自然科学基金青年项目、中国博士后科学基金（一等）和深圳市科技计划自由探索项目的研究资助。
教育及工作经历
2005.09-2009.07 大连理工大学 学士（生物技术）
2009.09-2014.07 北京大学 理学博士（细胞生物学）
2014.10-2016.09 北京大学深圳研究生院 博士后
2016.10-2020.09 北京大学深圳研究生院 助理研究员、副研究员
2020.09-至今 华南师范大学 特聘研究员
主持科研项目
1.中国博士后科学基金一等资助（2015M580017）：斑马鱼亨廷顿模型的建立及发病机制的研究。2015.09-2016.09。8万
2.深圳市知识创新计划（JCYJ20170818090542084）：先天性纯红细胞再生障碍性贫血疾病（DBA）的发病机理研究。2018.03-2020.03。30万
3.国家自然科学基金青年项目（31801209）：斑马鱼rpl18基因缺陷致使DBA病征的分子机制研究。2019.01-2021.12。24万。

研究领域

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近期论文

1. Chen, C., Lu M., Lin, S., Qin, W*. (2020) The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond-Blackfan anemia. Cell Death and Disease. 11(2), 135.
2. Bai, H., Liu,L., An, K., Lu X., Harrison, M., Zhao, Y., Yan, R., Lu, Z., Li, S., Lin, S., Liang, F*., Qin, W*. (2020) CRISPR/Cas9-mediated precise genome modification by a long single-stranded DNA template in zebrafish. Bmc Genomics.21 (7), 67.
3. Chen, C., Huang, H., Yan, R., Lin, S., Qin, W*. (2019) Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia. G3 (Bethesda) 9(12),4149-4157.
4. Qin, W*,#., Lu, X#., Liu, Y., Bai, H., Li, S. and Lin S*. (2018) Precise A.T to G.C base editing in the zebrafish genome. Bmc Biology. 16(1),139.
5. Qin, W#., Lu, X#., Lin,S*. (2018) Programmable base editing in zebrafish using a modified CRISPR-Cas9 system. Methods. 150, 19-23.
6. Lu, X., Liu, Y., Yan, G., Li, S., Qin, W*. and Lin, S*. (2018) Optimized Target-AID system efficiently induces single base changes in zebrafish. J Genet Genomics, 45, 215-217.
7. Yan, G., Yan, R., Chen, C., Chen, C., Zhao, Y., Qin, W., Veldman, M.B., Li, S. and Lin, S*. (2018) Engineering vascularized skeletal muscle tissue with transcriptional factor ETV2-induced autologous endothelial cells. Protein & cell. 10 (3) , 217-222.
8. Zhang, Y#., Qin, W#., Lu, X., Xu, J., Huang, H., Bai, H., Li, S. and Lin, S*. (2017) Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system. Nature Communications, 8, 118.
9. Burgess, S., Cheng, L., Gu, F., Huang, J., Huang, Z., Lin, S., Li, J., Li, W., Qin, W., Sun, Y. et al. (2016) Questions about NgAgo. Protein & cell, 7, 913-915.
10. Feng, Y., Chen, C., Han, Y., Chen, Z., Lu, X., Liang, F., Li, S., Qin, W*. and Lin, S*. (2016) Expanding CRISPR/Cas9 Genome Editing Capacity in Zebrafish Using SaCas9. G3 (Bethesda), 6, 2517-2521.
11. Veldman, M.B., Rios-Galdamez, Y., Lu, X.H., Gu, X., Qin, W., Li, S., Yang, X.W. and Lin, S*. (2015) The N17 domain mitigates nuclear toxicity in a novel zebrafish Huntington's disease model. Molecular Neurodegeneration, 10, 67.
12. Liang, F., Han, Y., Gao, H., Xin, S., Chen, S., Wang, N., Qin, W., Zhong, H., Lin, S., Yao, X. et al. (2015) Kaempferol Identified by Zebrafish Assay and Fine Fractionations Strategy from Dysosma versipellis Inhibits Angiogenesis through VEGF and FGF Pathways. Scientific Reports, 5, 14468.
13. Qin, W#., Liang, F#., Feng, Y., Bai, H., Yan, R., Li, S. and Lin, S*. (2015) Expansion of CRISPR/Cas9 genome targeting sites in zebrafish by Csy4-based RNA processing. Cell Research, 25, 1074-1077.
14. Qin, W., Chen, Z., Zhang, Y., Yan, R., Yan, G., Li, S., Zhong, H. and Lin, S*. (2014) Nom1 mediates pancreas development by regulating ribosome biogenesis in zebrafish. PLoS One, 9, e100796.
曾任Science Bulletin，Science Translational Medicine等权威期刊杂志审稿人。