个人简历

范瑞芳，女，河南省新乡人，博士，华南师范大学生命科学学院教授，博士研究生导师。
在国内外发表中英文论文50余篇，其中30篇被SCI及EI收录，“羧甲基聚合β－CD作为手性剂分离维拉帕米和布比卡因”一文获“第四届全国毛细管电泳及相关微分离分析技术学术报告会组委会”大会论文一等奖，曾获得华南师范大学科研工作优秀奖等荣誉，培养的多名研究生获得“广东省优秀学生”和“国家奖学金”等。
研究兴趣：（1）环境有机污染物生物监测与环境风险评价（2）环境污染物的毒理与健康效应。欢迎具有环境科学、生物技术、环境毒理学背景的学生报考研究生。
研究工作经历：
2014.12-今，华南师范大学生命科学学院，教授。
2010.09-2012.03，获国家留学基金委资助，赴美国加州公共卫生局（CaliforniaDepartmentofPublicHealth）访学一年半。
2006.12-2014.12，华南师范大学生命科学学院，副教授。
2001.12-2006.11，华南师范大学生命科学学院，助理研究员。
2000.03-2001.11，华南师范大学生命科学学院，实习研究员。
教育经历：
2004.03-2007.06，中科院广州地球化学研究所，博士。
1997.09-2000.02，北京理工大学，硕士。
1991.09-1995.06，河南师范大学，本科。
近5年主持/参与的国家、省部级基金项目有：
[1]国家自然科学基金（21777048），2018.01-2021.12，64万元，主持，在研。
[2]国家自然科学基金重点项目（41731279），2018.01-2022.12，323万元，第一参与人/子课题负责人，在研。
[3]广州市科技计划项目(201510010107)，20万，2015.06-2018.06，主持，结题。
[4]国家自然科学基金(21477041)，87万元，2015.01-2018.12，主持，结题。
[5]广东省自然科学基金(S2013010013183)，5万元，2013.10-2015.10，主持，结题。
[6]教育部留学回国人员科研启动基金(教外司留[2013]693号)，3万元，2013.07-2015.07，主持，结题。
[7]教育部博士点基金(20124407120005)，4万元，2012.12-2015.12，主持，结题。
[8]环境保护部全国重点地区环境与健康专项调查基金子课题(21111011101EHH(2011)-206)，8万元，2011.07-2013.02，主持，结题。

近期论文

【1】Effectsoflow-doseandperinatalexposuretobisphenolAonbraincellofoffspringmiceaswellasitsrelationshipswithalteredbehaviorofchildren,supportedbyNationalNaturalScienceFoundationofChina(grantNo.21777048),¥640,000,2017.01-2020.12.
【2】Effectsoflong-termandlow-doseexposuretobisphenolAonbraincellandbehaviorinseveralgenerationsofmiceduringperinatalperiod,supportedbytheGuangzhouKeyLaboratoryofEnvironmentalExposureandHealth(grantNo.GZKLEEH201607),¥50,000,2016.06-2018.06.
【3】RelationshipsbetweenpolycyclicaromatichydrocarbonexposurelevelsandDNAdamage,lungfunctionofchildren,supportedbyNationalNaturalScienceFoundationofChina(grantNo.21477041),¥870,000,2015.01-2018.12.
【4】EffectsofLong-termexposuretobisphenolAonbraincellandtheirrelationshipswiththechangeofchildrenbehavior,supportedbyScienceandTechnologyProgramofGuangzhou,China(grantNo.201510010107),¥200,000,2015.01-2017.12.
【5】RelationshipsbetweentheurinarybisphenolAexposureforkindergartenchildreninGuangzhou,theoxidativeDNAdamageandthedustconcentration,supportedbyNaturalScienceFoundationofGuangdong,China(grantNo.S2013010013183),¥50,000,2013.10-2015.10.
【6】PrimarystudyofaromaticcarcinogeniccompoundsinPM2.5airanditseffectsonchildreninGuangzhou,SupportedbyScientificResearchFoundationforReturnedScholars,MinistryofEducationofChina(grantNo.[2013]693),¥30,000,2013-2015.
【7】PrimarystudyofaromaticcarcinogeniccompoundsinPM2.5airanditseffectsonchildreninGuangzhou,supportedbyResearchFundfortheDoctoralProgramofHigherEducationofChina(grantNo.20124407120005),¥40,000,2013.0-2015.05.
【8】QA/QCsystemofthequantitationofhydroxylPAHinurine,supportedbyMinistryofEnvironmentalProtection,sub-fundingofenvironmentalhealthspecialsurveyofthekeyareaofChina(grantNo.21111011101EHH(2011)-206),¥80,000,2011.10-213.02.
【9】Children’sexposureleveltoPAHsinGuangzhouandtheirrelationshipswithDNAdamage,supportedbyOpenProjectofChinesestatekeylaboratoryoforganicchemistry(grantNoOGL-200706).¥20,000,2008.01-2009.12.
近年以通讯以及第一作者发表的代表性文章(Publicationsinthepastfiveyears):
(1)HaibinZhang,ZhouyuWang,LingxueMeng,HongxuanKuang,JianLiu,XuejingLv,QihuaPang,RuifangFan*,MaternalexposuretoenvironmentalbisphenolAimpairstheneuronsinhippocampusacrossgenerations,Toxicology,2020,432:152393.
(2)HongxuanKuang,YanyanDai,YonghongLi,CaihuiCha,WenhuiJiang,QihuaPang,HaibinZhang,RuifangFan*.TheassociationamongbloodBPDE-DNAadducts,seruminterleukin-8(IL-8)andoverallDNAdamageforchildrenwithpulmonarydisease.InternationalJournalofEnvironmentalHealthResearch,,2019,1-12.(SCI,IF=1.465)
(3)HongxuanKuang,YonghongLi,WenhuiJiang,PeiqiongWu,JianhuaTan,HaibinZhang,QihuaPang,RuifangFan*.Simultaneousdeterminationofurinary31VOCmetabolites,8-hydroxy-2'-deoxyguanosineandtrans-3'-hydroxy-cotininebyUPLC-MS/MS:Theeffectofisotopedinternalstandardsoneliminationofmatrixeffect,AnalyticalandBioanalyticalChemistry,2019,411:7841-7855.(IF2018=3.286)
(4)HaibingZhang,KuanghongXuan,YifanLuo,ShuhuaLiu,LingxueMeng,QihuaPang,RuifangFan*.Low-dosebisphenolAexposureimpairslearningandmemoryabilitywithalterationsofneuromorphologyandneurotransmittersinrats,ScienceoftheTotalEnvironment,2019,697:134036.（IF2018=5.589）
(5)QihuaPang#,YanruLi#,LingxueMeng,GuanyongLi,ZhiweiLuo,RuifangFan*.NeurotoxicityofBPA,BPSandBPBforthehippocampalcellline(HT-22):animplicationforthereplaceofBPAinplastics，Chemosphere,2019,226:545-552.(SCI2018=5.108,2区)
6)邝洪轩，张海彬，谭建华，雒亦凡，刘舒华，庞启华，李楚华，范瑞芳*.维生素C抗氧化-同位素内标稀释-超高效液相色谱串联质谱法同时测定新生期大鼠海马体神经递质的含量，色谱，2019，37（4）：404-411。
(7)LaiguoChen,GuochengHu,RuifangFan*,YanshanLv,YanyanDai,ZhenchengXu*.AssociationofPAHsandBTEXexposurewithlungfunctionandrespiratorysymptomsamongnon-occupationalpopulationnearthecoal-chemicalindustryinNorthernChina.EnvironmentInternational,2018,120:480-488.(SCI2018=7.943,1区)
(8)YanruLi,HaibinZhang,HongxuanKuang,RuifangFan*,CaihuiCha*,GuanyongLi,ZhiweiLuo,QihuaPang.RelationshipbetweenBisphenolAexposureandAttention-deficit/hyperactivitydisorder:Acase-controlstudyforprimaryschoolchildreninGuangzhou,China.EnvironmentalPollution,2018,235:141-149.(SCI2018=5.714,2区)
(9)YuanxiuZhou,ZhouyuWang,MinghanXia,SiyiZhuang,XiaobingGong*,JianwenPan,ChuhuaLi,RuifangFan*,QihuangPang,ShaoyouLu.NeurotoxicityoflowbisphenolA(BPA)exposureforyoungmalemice:AnimplicationforchildrenexposedtoenvironmentallevelofBPA,EnvironmentalPollution,2017,229:40-48.(SCI2017=4.358,2区)
(10)YanshanLv#,ShaoyouLu#,YanyanDai,CaiyanRui,YongjunWang,YanruLi,YuanxiuZhou,QihuaPang,RuifangFan*.HigherdermalexposureofcashierstoBPAanditsassociationwithDNAoxidativedamage,EnvironmentInternational,2017,98:69-74.SCI2017=7.297,1区).
(11)YanshanLv,CaiyanRui,YanyanDai,QihuaPang,YanruLi,RuifangFan*,ShaoyouLu*.ChildrenexposuretoBPAthroughdustandtheassociationofurinaryBPA,triclosanwithoxidativestressinGuangzhou,China.EnvironmentalScience:processes&impact,2016,18:1492-1499.(SCI,IF2016=2.592)
(12)ShaoyouLu,LuRen,JianzhangFang,JiajiaJi,GuihuaLiu,JianqingZhang,HuiminZhang,RuorongLuo,KaiLin,RuifangFan*.Traceelementscanincreaseurinary8-hydroxy-2’-deoxyguanosinelevel:acasestudyofcollegestudentsinGuangzhou,China.EnvironmentalScienceandPollutionResearch,2016,23:8484–8491.(SCI,IF2016=2.741)
(13)周苑秀，李敏杰，钟伟红,范瑞芳*.彗星电泳法测定双酚A对雄性小鼠脑细胞的DNA损伤.生态毒理学报，2016，11(2):666-671。
(14)JunnanLi#,ShaoyouLu#,GuihuaLiu,YuanxiuZhou,YanShanLv,JianwenShe,RuifangFan*.Co-exposuretopolycyclicaromatichydrocarbons,benzeneandtolueneandtheirdose-effectsonoxidativestressdamageinkindergarten-agedchildreninGuangzhou,China.ScienceoftheTotalEnvironment,2015,524-525:74-80.(SCI,IF2015=4.099,2区).
(15)RuifangFan*,BiyanZeng,XiaosuLiu,ChaoChen,QinweiZhuang,YongjunWang,MingliHu,YanshanLv,JunnanLi,YuanxiuZhou,ZhiYuan(William)Lin.Levelsofbisphenol-AindifferentpaperproductsinGuangzhou,Chinaandassessmentofhumanexposureviadermalcontact.EnvironmentalScience:Processes&Impacts,2015,17:667-673.(SCI,IF2015=2.401)
(16)RuifangFan*,DongliWang,JianwenShe.Methoddevelopmentforthesimultaneousanalysisoftrans,trans-muconicacid,1,2-dihydroxybenzene,S-phenylmercapturicacidandS-benzylmercapturicacidinhumanurinebyliquidchromatography/tandemmassspectrometery.AnalyticalMethods,2015,7:573-580.(SCI,IF2015=1.821)
(17)JunnanLi,RuifangFan*,ShaoyouLu*,DongruZhang，YuanxiuZhou,YanshanLv.ExposuretoPolycyclicAromaticHydrocarboncouldcausetheiroxidativeDNADamage:ACaseStudyforCollegeStudentsinGuangzhou,China.EnvironmentalScienceandPollutionResearch,2015,22:1770-1777.(SCI,IF2015=2.828)
(18)RuifangFan,JunnanLi,LaiguoChen*,ZhenchengXu*,DechunHe,YuanxiuZhou,YuanyuanZhu,FushengWei,JihuaLi.Biomassfuelsandcokeplantsareimportantsourcesofhumanexposuretopolycyclicaromatichydrocarbons,benzeneandtoluene.EnvironmentalResearch,2014,135:1–8.(SCI,IF2014=4.373)
(19)RuifangFan*,DongliWang,ChuanweiMao,ShangkangOu,ZhixiaLian,ShaolingHuang,QiongshanLin,RunhaoDing,JianwenShe.Preliminarystudyofchildren’sexposuretoPAHsanditsassociationwith8-hydroxy-2’-deoxyguanasineinGuangzhou,China.EnvironmentInternational,2012,42:53-58.(SCI,IF2012=6.248)
(20)RuifangFan,RobertRamage,DongliWang,JunqiangZhou,JianwenShe*.Determinationoftenmonohydroxylatedpolycyclicaromatichydrocarbonsbyliquid-liquidextractionandliquidchromatography/tandemmassspectrometry.Talanta,2012,93:383-395.(SCI,IF2012=3.498)
(21)RuifangFan,DongliWang,RobertRamage,JianwenShe*.Fastandsimultaneousdeterminationofurinary8-hydroxy-2'-deoxyguanosineandtenmonohydroxylatedpolycyclicaromatichydrocarbonsbyliquidchromatography/tandemmassspectrometery.ChemicalResearchinToxicology,2012,25(2)491-499.(SCI,IF2012=3.667.)
任广东省环境诱变剂协会理事,长期担任EnvironmentInternational,EnvironmentalScience&Technology,ScienceofTotalEnvironment,EnvironmentalResearch,ScientificReports,Chemosphere等杂志的审稿人。