个人简历

2002年获光学博士学位。2002.5—2003.1德国国际生物物理研究所（合作教授Fritz-Albert Popp & Roeland Van Wijk）从事生物光子学的研究，在柏林自由大学的生物化学与分子生物学研究所（合作教授Werner Reutter & Hua Fan）从事分子生物学方面的实验研究（作为访问学者获DAAD资助）；2011.12—2013.4在美国杜克大学环境学院(Nicholas School of the Environment) Xinnian Dong实验室访学；2013.5—2016.2在美国北卡罗来纳大学教堂山分校(UNC at Chapel Hill)生物学系Alan M. Jones实验室、生物化学与生物物理系Hengming Ke实验室从事合作研究。近年在超敏反应初期自噬在NPR1代谢中的角色，自噬在糖诱导的RGS1代谢中的作用, 纳米转基因治疗病害等研究领域做过系列研究。在Autophagy, Biology of the Cell, Cell Transplantation, Frontiers in plant science等期刊上发表30余篇SCI收录的研究论文，承担并结题了国家自然科学基金项目2项。《生物光子学的基础与应用研究》获2005年度广东省科学技术奖一等奖（排名第四）。
学习经历
2013.5—2014.4美国北卡罗来纳大学教堂山分校(UNC at Chapel Hill)生物学系从事自噬在饥饿与糖诱导下在G蛋白信号转导调节因子（RGS）合成和降解的作用研究。访问学者
2011.12—2013.4美国杜克大学环境学院（Nicholas School of the Environment）从事植物抗病过程中自噬基因功能的合作研究 。访问学者
2002. 5—2003.1德国国际生物物理研究所从事生物光子学的研究,在柏林自由大学生物化学与分子生物学研究所从事分子生物学方面的实验研究（作为访问学者获DAAD资助）
1999.9—2002.12华南师范大学激光生命研究所，获博士学位
1994.9—1997.6南京农业大学生命科学学院，获硕士学位
工作经历
1997.8—今 华南师范大学生命科学学院/生物光子学研究院系助教，讲师，副教授，教授。从事生物化学、细胞生物学的研究及教学工作。
获奖
2005年广东省科学技术奖一等奖“生物光子学的基础与应用研究”的主要参与者（排名第四）。
2004年获得“为了明天”双语教学比赛一等奖（校级）
2006年获得“为了明天”教学比赛一等奖的第一名（校级）

研究领域

自噬相关基因的功能研究；纳米转基因技术在植物及动物体内的应用基础研究。""

近期论文

1. Wenjun Gong, Bingcong Li, Baihong Zhang, Wenli Chen* ATG4 Mediated Psm ES4326/AvrRpt2-induced Autophagy Dependent on Salicylic Acid in Arabidopsis thaliana. Int J Mol Sci. 2020;21(14):5147. (Correspondence author)
2. Wen-xue Lei, Zi-shuai An, Bai-hong Zhang, Qian Wu, Jin-Ming Li and Wen-li Chen*. Construction of Gold-siRNANPR1 nanoparticles for effective and quick silencing of NPR1 in Arabidopsis thaliana. RSC Advances, 2020,10, 19300 –19308. (Correspondence author)
3. Yue Jiao, Miroslav Srba,Jingchun Wang and Wenli Chen. Correlation of Autophagosome Formation with Degradation and Endocytosis Arabidopsis Regulator of G-Protein Signaling (RGS1) through ATG8a. Int. J. Mol. Sci. 2019, 20(17), 4190 (Correspondence author)
4. Zhang S, Xu W, Gao P, Chen W, Zhou Q. Construction of dual nanomedicines for the imaging and alleviation of atherosclerosis. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):169-179.
5. Wan Xu, Shuihua Zhang, Quan Zhou, Wenli Chen.VHPKQHR peptide modified magnetic mesoporous nanoparticles for MRI detection of atherosclerosis lesions. Artificial Cells, Nanomedicine, and Biotechnology, 2019, 4(1), 2440–2448 (Correspondence author)
6. Yue Jiao, Wenxue Lei, Wan Xu & Wen-Li Chen: Glucose signaling, AtRGS1 and plant autophagy, Plant Signaling & Behavior, 2019,e1607465 1-3(Correspondence author)
7. Zhang W, Xu W, Chen W*, Zhou Q. Interplay of Autophagy Inducer Rapamycin and Proteasome Inhibitor MG132 in Reduction of Foam Cell Formation and Inflammatory Cytokine Expression. Cell Transplant. 2018, 27(8):1235-1248. (Correspondence author)
8. Quanquan Yan, Jingchun Wang, Zheng Qing Fu, Wenli Chen*（2017）Endocytosis of AtRGS1 is Regulated by the Autophagy Pathway after D-glucose Stimulation. Frontiers in plant science. 2017; 8: 1229. (Correspondence author)
9. Zhang W, Zhang S, Xu W, Zhang M, Zhou Q, Chen W*. The function and magnetic resonance imaging of immature dendritic cells under ultrasmall superparamagnetic iron oxide (USPIO)-labeling. Biotechnol Lett. 2017, 39(7):1079-1089. (Correspondence author)
10. Gao YY, Wang XD, Ma C, Chen WL*. EDS1-mediated activation of autophagy regulates Pst DC3000 (AvrRps4)-induced programmed cell death in Arabidopsis. Acta Physiol Plant 2016, 38:150 (Correspondence author)
11. Wang XD, Gao YY, Yan QQ, Chen WL*. Salicylic Acid promotes Autophagy via NPR3 and NPR4 in Arabidopsis Senescence and Innate Immune Response. Acta Physiol Plant 2016, 38: 241(Correspondence author)
12. Liu HB, Wang XD, Zhang YY, Dong JJ, Ma C, Chen WL*. NADPH oxidase RBOHD contributes to autophagy and hypersensitive cell death during the plant defense response in arabidopsis thaliana. Biologia Plantarum. 2015, 59(3): 570-580. (Correspondence author)
13. Wang J, Ma C, Zhang M, Yang L, Chen W*. ATG5 is required to limit cell death induced by Pseudomonas syringae in Arabidopsis and may be mediated by the salicylic acid pathway. Acta Physiol Plant. 2015, 37:1731-5(Correspondence author)
14. Zhang M, Zhou J, Wang J, Zhou Q, Fang J, Zhou C, Chen W*. Superparamagnetic iron oxide labeling limits the efficacy of rabbit immature dendritic cell vaccination by decreasing their antigen uptake ability in a lysosome- dependent manner. Biotechnol Lett 2015, 37(2): 289-298 (Correspondence author)
15. Yu M, Wang J, Liu W, Qin J, Zhou Q, Wang Y, Huang H, Chen W, Ma C. Effects of tamoxifen on the sex determination gene and the activation of sex reversal in the developing gonad of mice. Toxicology. 2014, 321: 89-95.
16. Jing Zhou, Fuyuan Yang, Quan Zhou, Kanrong Yang and Wenli Chen*. Magnetic Resonance Imaging Tracking of Ultra Small Superparamagnetic Iron Oxide Labeled Rabbit Dendritic Cells.Experimental Biology and Medicine. 2014, 239(1):13-23. (Correspondence author)
17. Junjian, Dong, Wenli Chen*. The Role of Autophagy in Chloroplast Degradation and Chlorophagy in Immune Defenses during Pst DC3000 (AvrRps4) Infection. PLOS ONE, 2013,8(8):e73091 1-16. (Correspondence author)
18. Liang MJ, Zhou Q, Yang KR, Yang XL, Fang J, Chen WL, Huang Z. Identify changes of brain regional homogeneity in bipolar disorder and unipolar depression using resting-state fMRI. PLoS One. 2013, 8(12): e79999 1-8
19. Fuyuan Yang, Mingxi Yu, Quan Zhou, Wenli Chen*, Peng Gao, Zheng Huang. Effects of iron oxide nanoparticle labeling on human endothelial cells. Cell Transplantation. 2012, 21（9）: 1805-1820. (Correspondence author)
20. Wenli Chen (one of authors). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 2012,8(4): 445-544.
21. Quan Zhou, Kanrong Yang, Peng Gao, Wenli Chen, Dayan Yang, Minjie Liang, and Lin Zhu. An Experimental Study on MR Imaging of Atherosclerotic Plaque With SPIO Marked Endothelial Cells in a Rabbit Model. Journal of Magnetic Resonance Imaging, 2011, 34(6):1325-32.
22. Weina Zhang, Wenli Chen*. Role of salicylic acid in alleviating photochemical damage and autophagic cell death induction of cadmium stress in Arabidopsis thaliana.Photochem. Photobiol. Sci., 2011, 10(6): 947-955. (Correspondence author)
23. Lijuan Yun, Wenli Chen*. SA and ROS are involved in methyl salicylate-induced programmed cell death in Arabidopsis thaliana.Plant Cell Rep. 2011, 30(7): 1231–1239. (Correspondence author)
24. Chen Zhiqiang, Chen Wenli*, Yang Chengwei. Effects of Exogenous Salicylic Acid on Photosynthesis in Arabidopsis Leaves Based on Fluorescence Spectra and Delayed Fluorescence Technique.Spectroscopy and Spectral Analysis, 2009, 29(8): 2208-2212.
25. Liu Yang, Junjian Dong, Wenli Chen*. Autophagy and declined photosynthesis in Arabidopsis during pathogenic Pst DC3000 infection. Acta Biophysica Sinica. 2011, 27(6):517-527.
26. Gao Lin, Zhang Weina, Chen Wenli*. Cadmium toxicity and autophagy in Arabidopsis seedlings.Acta Biophysica Sinica. 2011, 27(8):676-686.
27. Mingxi Yu.，Wenli Chen*，Zhou Q，Gao P. Study on ASTC-a-1 cells labeled with superparamagnetic iron oxide and its magnetic resonance imaging.Experimental Biology and Medicine, 2010，235(9):1053-61. (Correspondence author)
28. YuHua Bi, WenLi Chen*, WeiNa Zhang, Quan Zhou, LiJuan Yuan and Da Xing, Production of reactive oxygen species, impairment of photosynthetic function and dynamic changes of mitochondria are early events in cadmium induced cell death in Arabidopsis thaliana. Biology of the Cell, 2009,101(11)：629－643. (Correspondence author)
29. Quan Zhou, Yang Dong, Li Huang, Shihua Yang, Wenli Chen. Study of cerebrovascular reserve capacity by magnetic resonance perfusion weighted imaging and photoacoustic imaging. Magnetic Resonance Imaging, 2009, 27: 155-162.
30. Wenli Chen*, Da Xing and Roeland Van Wijk．Chemiluminescence during rice seed imbibition at different temperatures. Luminescence 2006, 21（1）: 31-35. (Correspondence author)
31. Wenli Chen, Da Xing* and Weigui Chen. Rapid Detection of Aspergillus flavus Contamination in Peanut with Novel Delayed Luminescence Spectra. Photochemistry and Photobiology, 2005，81（6）：1361-1365.
32. Wenli Chen*, Roeland Van Wijk and Da Xing. Effects of isoflurane on measurements of delayed lumininescence in Acetabularia acetabulum, Luminescence 2005, 20: 16-19. (Correspondence author)
33. Wenli Chen, Da Xing, Shici Tan, et al. Imaging of ultra-weak bio-chemiluminescence and singlet oxygen generation in germination soybean in response to wounding. Luminescence, 2003, 18(1): 37-41.
34. Wenli Chen, Da Xing, Juan Wang and Yonghong He. Rapid determination of rice seed vigour by spontaneous chemiluminescence and singlet oxygen generation during early imbibition, Luminescence, 2003, 18(1): 19-24.
35. Wenli Chen, Da Xing et al. Determination of Rice Seed Vigor with Different Aging Degrees by Ultraweak Chemiluminescence during Early Imbibition. Acta Botanica Sinica, 2002, 44(11): 1376-1379.
曾担任国际刊物Journal of Chromatography A，Luminescence，Human and Experimental Toxicology，Molecular Biotechnology等的审稿人。获奖
2006年-2010年为广东省高等学校\"千、百、十\"工程（校级）培养对象。