个人简历

教育经历\r
2004.09-2008.06 山东大学药学院，药学专业，理学学士\r
2008.09-2013.12 山东大学药学院，药物化学专业，理学博士\r
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工作经历\r
2013.12-2015.12，复旦大学药学院，药物化学专业，博士后\r
2016.03-至今，河南师范大学化学化工学院讲师\r
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获得荣誉与奖励\r
河南师范大学优秀教师

研究领域

""1、小分子抗肿瘤药物的设计合成\r
2、基于靶点的先导化合物的设计和结构优化""""

近期论文

Chunhua Ma, Yu Tian, Junyan Wang, Xing He, Yuqin Jiang*, Bing Yu*, Visible-Light-Driven Transition-Metal-Free Site-Selective Access to Isonicotinamides.Organic Letters, 2022, 24, 8265-8270.\r
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Jin Wang, Qingyuan Song, Xing He, Chunhua Ma,* Yuqin Jiang,* and Jing Fan,* Visible light-promoted, photocatalyst-free decarboxylative alkylation of 2H-indazoles via electron donor-acceptor complex activation. New Journal of Chemistry, 2022, 46, 16436-16439.\r
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Chunhua Ma, Hui Meng, Jing Li, Xianguang Yang, Yuqin Jiang*, Bing Yu*, Photocatalytic Transition-Metal-Free Direct 3-Acetalation of Quinoxaline-2(1H)-ones, Chinese Journal of Chemistry, 2022, 40, 2655-2662.\r
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Chunhua Ma, Yue Wang, Guang Chen, Jingyi Li, Yuqin Jiang, Xinying Zhang,* and Xuesen Fan*. Divergent construction of 3-(indol-2-yl)succinimide/maleimide and fused benzodiazepine skeletons from 2-(1H-indol-1-yl)anilines and maleimides. Organic Chemistry Frontiers, 2022, 9, 4663-4669.\r
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Chunhua Ma, Hui Meng, Xing He, Yuqin Jiang*, Bing Yu*, Visible-Light-Promoted Transition-Metal-Free Construction of 3-Perfluoroalkylated Thioflavones, Frontiers in Chemistry, 2022, 10, 953978.\r
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Chunhua Ma, Lu Zhao, Xing He, Yuqin Jiang,* and Bing Yu*, Visible-light-induced direct 3-ethoxycarbonylmethylation of 2-aryl-2H-indazoles in water, Organic Chemistry Frontiers, 2022, 9, 1445-1450.\r
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Chunhua Ma*, Qingyun Li, Minghao Zhao, Goujie Fan, Jie Zhao, Dandan Zhang, Shouning Yang, Shuting Zhang, Dingding Gao, Longfei Mao, Liang Zhu, Wei Li, Guiqing Xu,* Yuqin Jiang,* and Qingjie Ding*. Discovery of 1-Amino-1H-imidazole-5-carboxamide Derivatives as Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitors. Journal of Medicinal Chemistry, 2021, 64, 16242−16270.\r
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Chunhua Ma, Yu Ji, Jie Zhao, Xing He, Shuting Zhang,* Yuqin Jiang,* and Bing Yu*. Transition-metal-free three-component acetalation-pyridylation of alkenes via photoredox catalysis. Chinese Journal of Catalysis, 2022, 43, 571-583.\r
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Dandan Zhang#, Guiqing Xu#, Jie Zhao#, Yue Wang, Xiaofang Wu, Xing He, Wei Li, Shuting Zhang, Shouning Yang, Chunhua Ma*, Yuqin Jiang*, Qingjie Ding*. Structure-activity relationship investigation for imidazopyrazole-3-carboxamide derivatives as novel selective inhibitors of Bruton's tyrosine kinase. European Journal of Medicinal Chemistry, 2021, 225, 113724.\r
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Chunhua Ma, Zhiwen Feng, Jing Li, Dandan Zhang, Wei Li,Yuqin Jiang*and Bing Yu*. Photocatalytic Transition-Metal-Free Direct 3-Alkylation of 2-Aryl-2H-Indazoles in Dimethyl Carbonate, Organic Chemistry Frontiers, 2021, 8, 3286-3291.\r
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Yuqin Jiang, Jing Li, Zhiwen Feng, Guiqing Xu, Xin Shi, Qingjie Ding, Wei Li, Chunhua Ma* and Bing Yu*. Ethylene glycol: a green solvent for visible light-promoted aerobic transition metal-free cascade sulfonation/cyclization reaction, Advanced Synthesis & Catalysis, 2020, 362(13), 2609-2614.\r
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Zhiwen Feng, Jing Li, Yuqin Jiang, Yu Tian, Guiqing Xu, Xin Shi, Qingjie Ding, Wei Li, Chunhua Ma* and Bing Yu*, Transition-metal-free sulfonylations of methylthiolated alkynones to synthesize 3-sulfonylated thioflavones, New Journal of Chemistry, 2020, 44, 14786-14790.\r
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Jiaxuan Shen,* Nannan Li, Yanjiang Yu, and Chunhua Ma*. Visible-Light-Induced Oxidation/[3 + 2] Cycloaddition/Oxidative Aromatization to Construct Benzo[a]carbazoles from 1,2,3,4-Tetrahydronaphthalene and Arylhydrazine Hydrochlorides, Organic Letter 2019, 21(17), 7179-7183.\r
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Ma, C.; Miao, Y.; Zhao, M.; Wu, P.; Zhou, J.; Li, Z.; Xie, X.; Zhang, W.*, Synthesis of 2-aminothiazoles from styrene derivatives mediated by 1,3-dibromo-5,5-dimethylhydrantoin (DBH). Tetrahedron 2018, 74 (27), 3602-3607.\r
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Ma, C.; Fan, G.; Wu, P.; Li, Z.; Zhou, Y.; Ding, Q.; Zhang, W.*, 1,3-Dibromo-5,5-dimethylhydantoin mediated oxidative amidation of terminal alkenes in water. Organic & Biomolecular Chemistry 2017, 15 (46), 9889-9894.\r
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Ma, C.; Cao, J.; Liang, X.; Huang Y.; Wu, P; Li, Y.; Xu, W.; Zhang, Y.*; Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, Synthesis and activity evaluation. European Journal of Medicinal Chemistry 2016, 108, 21-27.\r
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Ma, C.; Li, X.; liang, X.; Jin, K.; Cao, J.; Xu, W.*, Novel β-dicarbonyl derivatives as inhibitors of aminopeptidase N (APN). Bioorganic & Medicinal Chemistry Letters2013, 23 (17), 4948-4952.\r
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Ma, C.; Jin, K.; Cao, J.; Zhang, L.; Li, X.; Xu, W.*, Novel leucine ureido derivatives as inhibitors of aminopeptidase N (APN). Bioorganic & Medicinal Chemistry 2013, 21 (7), 1621-1627.