个人简历

姜玉钦，河南镇平人。药物化学和制药工程硕士生导师，教务处副处长。
教育经历：
1998.09-2002.07 河南师范大学化学与环境科学学院，精细化工专业，工学学士，指导教师 娄向东教授；
2002.09-2005.07 河南师范大学化学与环境科学学院，应用化学专业，工学硕士，导师 李伟教授；
2005.09-2008.12 南开大学高分子化学研究所，高分子化学与物理专业，理学博士，导师 陈永胜教授。
工作经历：
2009.01-2010.12 郑州大学化学系，分析化学博士后，合作导师 屈凌波教授；
2011.01-2015.03 河南师范大学化学与环境科学学院，讲师，硕士生导师；
2015.04-2020.10 河南师范大学化学化工学院，副教授；
2020.11至今 河南师范大学教务处，副处长。
讲授课程：
《药物分析》《化学制药工艺学》《药物分析及制药检测常用技术》
近年来主持的主要科研项目:
1、河南省科技创新杰出青年人才支持计划：高品质曲克芦丁原料药合成关键技术及产业化研究，2017.01-2018.12，30万元。
2、河南省产学研项目：维脑路通原料药生产新工艺及产业化研究，2015.01-2016.12，25万元。
3、横向项目：曲克芦丁化学合成新工艺，2014.05-2016.12，50万元。
4、横向项目：阿托伐他汀钙原料药新工艺研究，2017.11-2021.12，100万元。
5、横向项目：抗肿瘤新药的研究与开发，2019.01-2022.01，100万元。
6、横向项目：抗过敏药物工艺开发及DMF文件制作，2019.10-2021.02，150万元。
7、河南省高等教育教学改革研究与实践重点项目：生物与医药硕士创新及联合培养基地建设研究与实践，2019-2021，3万元。
8、河南省专业学位研究生精品教学案例项目：制药工艺与技术，2021-2022，3万元。
授权专利：
7、姜玉钦 等，一种阿托伐他汀钙中间体ATS-9的纯化方法，ZL 201811169986.X，2020年。
6、姜玉钦 等，一种高纯度福多司坦的制备方法，ZL 201810560947.6，2020年。
5、姜玉钦 等，一种高含量曲克芦丁的制备方法，ZL 201710119984.9，2020年。
4、姜玉钦 等，一种奈拉西坦的制备方法，ZL 201410766319.5，2017年。
3、姜玉钦 等，一种采用自吸式搅拌高压釜制备曲克芦丁的方法，ZL 201410766698.8，2017年。
2、姜玉钦 等，具有抑菌活性的烯唑醇-1,2,3-三氮唑类化合物及其制备方法，ZL 201410184618.8，2016年。
1、姜玉钦 等，一种沙坦联苯的制备方法，ZL 201310383875.X，2015年。
科技奖励：
2、曲克芦丁合成关键技术创新及产业化，河南省教育厅科技成果奖一等奖，第一完成人，2020年。
1、阿托伐他汀钙关键技术研究与产业化，河南省科学技术进步奖叁等奖，第四完成人，2014年。
个人荣誉：
获河南省抗击新冠肺炎疫情先进个人；河南省科技创新杰出青年；河南省优秀硕士学位论文指导教师；河南省高校科技管理工作先进工作者；河南省高等学校优秀共产党员；新乡市九三学社抗击新冠肺炎疫情先进个人暨社会服务先进个人；中国“互联网+”大学生创新创业大赛全国铜奖指导教师；河南师范大学“青年五四奖章”、“优秀教师”、“三育人先进个人”、“研究生优秀指导教师”等。
Education:
1998.09-2002.06 School of Chemistry and Environmental Sciences, Henan Normal University, Bachelor of Engineering;
2002.09-2005.06 School of Chemistry and Environmental Sciences, Henan Normal University, Master of Engineering;
2005.09-2008.12 Institute of Polymer Chemistry, Nankai University, Doctor of Science.
Professional Experience:
2011.01, School of Chemistry and Environmental Sciences, Henan Normal University;
2015.04, School of Chemistry and Chemical Engineering, Henan Normal University, associate professor;
2009.01-2011.01, Department Chemistry, Zhengzhou University, analytical chemistry postgraduate.
Research Support:
1、Innovative Talents Program of Henan Province (No. 174100510025): Research on the key technology and industrialization of high-purity bulk drug troxerutin, Role: PI, 2017.1-2018.12, ￥300K.
2、Research on the new technology and industrialization of drug Venoruton, Role: PI, 2015.1-2016.12,￥250K.
3、New synthetic process for troxerutin, Role: PI, 2014.5-2016.12, ￥500K.
4、New synthetic process for atorvastatin calcium, Role: PI, 2017.11-2021.12, ￥1000K.
5、Anti-tumor drug design and synthesis, Role: PI, 2019.01-2022.01, ￥1000K.
6、New synthetic process for antiallergic agent, Role: PI, 2019.10-2021.02, ￥1500K.
7 、Postgraduate Education Reform Project of Henan Province, Role: PI, 2019-2021, ￥30K.

研究领域

1、抗肿瘤创新药物
2、药物合成工艺
3、有机反应方法学
4、高分子生物医用材料""

近期论文

19、Chunhua Ma, Ming Chen, Zhiwen Feng, Yan Zhang, Jin Wang, Yuqin Jiang*, and Bing Yu*. Functionalization of imidazo[1,2-a]pyridines via radical reactions. New Journal of Chemistry, 2021, 45, 9302-9314.
18、Chunhua Ma, Zhiwen Feng, Jing Li, Dandan Zhang, Wei Li, Yuqin Jiang* and Bing Yu*. Photocatalytic transition-metal-free direct 3-alkylation of 2-aryl-2h-indazoles in dimethyl carbonate, Organic Chemistry Frontiers, 2021, DOI: 10.1039/D1QO00064K.
17、Yusang Xia, Ling Yan, Guojiang Mao, Wenli Jiang, Wenxin Wang, Yongfei Li, Yuqin Jiang*, and Chunyan Li*. A novel HPQ-based fluorescent probe for the visualization of carbon monoxide in zebrafish, Sensors and Actuators B: Chemical, 2021, 340, 129920 (1-7).
16、Yuqin Jiang, Pengfei Li, Jie Zhao, Bingxian Liu*, and Xingwei Li*. Iodonium ylides as carbene precursors in Rh(III)-catalyzed C-H activation, Organic Letters, 2020, 22(19), 7475-7479.
15、Yuqin Jiang, Lu Jiang, Yuanyuan Pang, Dan Kai, Xiaoshan Fan*, and Zibiao Li*. Surface migration of fluorinated-siloxane copolymer with unusual liquid crystal behavior for highly efficient oil/water separation, ACS Applied Polymer Materials, 2020, 2, 3612-3620.
14、Yuqin Jiang, Jing Li, Zhiwen Feng, Guiqing Xu, Xin Shi, Qingjie Ding, Wei Li, Chunhua Ma* and Bing Yu*. Ethylene glycol: a green solvent for visible light-promoted aerobic transition metal-free cascade sulfonation/cyclization reaction, Advanced Synthesis & Catalysis, 2020, 362(13), 2609-2614.
13、Yuqin Jiang, Pengfei Li, Juanjuan Wang, Jie Zhao, Yang Li, Yawen Zhang, Junbiao Chang*, Bingxian Liu* and Xingwei Li*. Rh(III)-catalyzed coupling of acrylic acids and ynenones via olefinic C-H activation and Michael addition, Organic Letters, 2020, 22(2), 438-442.
12、Yuqin Jiang, Yanyan Li, Tingting Yang, Xin Shi*, Huajun Suo, Weiwei Zhang* Guiqing Xu and Wei Li*. Design, synthesis, and antilung adenocarcinoma activity research of novel paeonol Schiff base derivatives containing a 1,2,3-triazole moiety, Journal of the Chinese Chemical Society, 2020, 67(1), 165-171.
11、TingtingYang, Xin Shi, Libing Guo, Shaohua Gu, Weiwei Zhang, Guiqing Xu, Wei Li* and Yuqin Jiang*. Design, synthesis, and antitumor activity of novel paeonol derivatives containing the 1,4-benzoxazinone and 1,2,3-triazole moieties, Journal of Chemical Research, 2019, 43(7-8), 241-247.
10、Yuqin Jiang, Kai Wu, Qian Zhang,* Keqing Li, Yanyan Li, Pengyang Xin, Weiwei Zhang and Haiming Guo*. A dual-responsive hyperbranched supramolecular polymer constructed by cooperative host-guest recognition and hydrogen-bond interactions, Chemical Communications, 2018, 54, 13821-13824.
9、Yuqin Jiang, Kai Wu, Liming Fan, Jinglin Zhao, Yuqing Yang, Weiwei Zhang* and Guiqing Xu*. Cu(OAc)2H2O/NH2OH·HCl/CH3COONa: A facile and efficient catalyst system for copper-catalyzed azide-alkyne click reactions in water, Journal of the Chinese Chemical Society, 2018, 65, 505-510.
8、Yuqin Jiang, Shuhong Jia, Xiyong Li, Yamin Sun, Wei Li, Weiwei Zhang, Guiqing Xu. An efficient NaHSO3-promoted protocol for chemoselective synthesis of 2-substituted benzimidazoles in water, Chemical Papers, 2018, 72, 1265-1276.
7、Yuqin Jiang, Huajun Suo, Yaru Zhao, Xiyong Li, Yamin Sun, Xingfeng Li, Wenpei Dong, Wei Li, Weiwei Zhang* and Guiqing Xu. DBU-promoted Cu(OAc)2·H2O-catalysed coupling reactions of aryl iodides and sodium azide, Journal of Chemical Research, 2018, 42, 247-250.
6、Yuqin Jiang, Kai Wu, Xuxia Tan, Dandan Zhang, Wenpei Dong, Wei Li, Guiqing Xu and Weiwei Zhang*. [bmim]PF6/KOH: a recyclable catalytic system for an azide-arylacetaldehyde [3+2] cycloaddition, Journal of Chemical Research, 2017, 41, 631-635.
5、Yuqin Jiang, Shuhong Jia, Xiyong Li, Yamin Sun, Wei Li, Weiwei Zhang* and Guiqing Xu*. Design, synthesis, and antifungal evaluation of novel benzoxazole derivatives containing a 1,2,3-triazole moiety, Journal of the Chinese Chemical Society, 2017, 64, 1197-1202.
4、Yuqin Jiang,* Xingfeng Li, Yaru Zhao, Shuhong Jia, Mingrui Li, Zhiqi Zhao, Ruili Zhang, Wei Li and Weiwei Zhang*. An efficient CuI/DBU-catalyzed one-pot protocol for synthesis of 1,4-disubstituted 1,2,3-triazoles, RSC Advances, 2016, 6, 110102-110107.
3、Yuqin Jiang,* Xing He, Weiwei Zhang, Xingfeng Li, Niu Guo, Yaru Zhao, Guiqing Xu* and Wei Li. Metallic copper wire: a simple, clear and reusable catalyst for the CuAAC reaction in supercritical carbon dioxide, RSC Advances, 2015, 5, 73340-73345.
2、Weiwei Zhang, Baoqi Ren, Yuqin Jiang* and Zhiguo Hu*. Carboxymethylpullulan promoted Cu2O-catalyzed Huisgen-click reaction, RSC Advances, 2015, 5, 12043-12047.
1、Weiwei Zhang, Xing He, Baoqi Ren, Yuqin Jiang* and Zhiguo Hu*. Cu(OAc)2·H2O-an efficient catalyst for Huisgen-click reaction in supercritical carbon dioxide, Tetrahedron Letters, 2015, 56, 2472-2475.
河南省科技创新杰出青年
河南省教育厅学术技术带头人
河南省手性醇类药物工程技术研究中心副主任
化学制药及生物医用材料河南省工程实验室副主任
河南省药学会药物化学专业委员会常委