个人简历

本科郑州大学化学系，博士毕业于中国科学院上海有机化学研究所，获2020年“Thieme Chemistry Journal Award”国际学术期刊奖，2020年 河南省优秀青年基金，邮箱地址：baidachang@126.com.\r
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教育经历：\r
2005.09 - 2009.07: 郑州大学，化学专业，理学学士\r
2009.09 - 2014.07: 中国科学院上海有机化学研究所，有机化学专业，理学博士（硕博连读），导师：侯雪龙 研究员\r
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工作经历：\r
2014.07 - 2015.08: 中科院上海有机所金属有机国家重点实验室，助理研究员\r
2015.10–2016.10: 美国内布拉斯加医学研究中心，博士后\r
2016.11-2020.04：河南师范大学，讲师\r
2020.04-至今：河南师范大学，副教授\r
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近年来主持的主要科研项目:\r
1， 国家自然科学基金-青年项目，铜催化肟酯与缺电子烯烃的环加成反应，2019-2021， 26万\r
2. 河南省优秀青年科学基金，过渡金属催化不对称C-C/C-O 键活化反应研，2020-2023，25万元\r
3，河南省高等学校重点科研项目计划，具有C2对称的手性联苯类环戊二烯基铑络合物的合成及其应用研究，2018-2019，5万

研究领域

""1，发展以绿色合成化学为导向的新反应方法和技术，研究过渡金属催化（铜，镍，铑，钯）的新型反应模式，包括不对称催化反应体系。\r
2，致力于新反应方法学的发展及其选择性调节与控制，将发展的方法应用到药物分子的合成中。""""

近期论文

1.Bai, Da-Chang.*; Wu, Fen.; Chang, Ling-Na.;Wang, Man-Man.; Wu, Hao.; Chang, Jun-Biao.* Highly Regio- and Enantioselective Hydrosilylation of gem-Difluoroalkenes by Nickel Catalysis. Angew. Chem. Int. Ed. 2022, doi:10.1002/anie.202114918. \r
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2.Bai, Da-Chang.*; Yu, Yan-Jiang.; Guo, Hai-Ming.; Chang, Jun-Biao.; Li, Xing-Wei.* Nickel(0)-Catalyzed Enantioselective [3+2] Annulation of Cyclopropenones and a,b-Unsaturated Ketones/Imines.Angew. Chem. Int. Ed. 2020, 59, 2740-2744. (IF = 12.257, Highlight by Synfacts 2020.16.641)\r
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3. Bai, Da-Chang.; Wang, Xue-Li.; Zheng, Guang-Fan.; Li, Xing-Wei.* Redox-Divergent Synthesis of Fluoroalkylated Pyridines and 2-Pyridones through Cu-Catalyzed N-O Cleavage of Oxime Acetates. Angew. Chem. Int. Ed. 2018, 57, 6633-6637. (IF = 12.257)\r
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4. Bai, Da-Chang.*;Xu, Teng.; Ma, Chao-Rui.; Zheng, Xin.; Liu, Bing-Xian.; Xie, Fang.; Li, Xing-Wei.* Rh(III)-Catalyzed Mild Coupling of Nitrones and Azomethine Imines with Alkylidenecyclopropanes via C−H Activation: Facile Access to Bridged Cycles. ACS Catal. 2018, 8, 4194-4200. (IF = 11.384)\r
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5. Bai, Da-Chang. (#); Xia, Jin-Tao. (#); Song, Fang-Fang .; Li, Xue-Yan .; Liu, Bing-Xian.; Liu, Li-Hong.; Zheng, Guang-Fan.; Yang, Xi-Fa.; Sun, Jia-Qiong, * Li, Xing-Wei.* Rhodium(III)-catalyzed diverse [4 + 1] annulation of arenes with 1,3-enynes via sp3/sp2 C–H activation and 1,4-rhodium migration. Chem. Sci. 2019, 10. 3987-3993.(#: co-first authors, IF = 9.556)\r
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6. Bai, Da-Chang.; Yu, Fei-Le.; Wang, Wan-Ying.; Chen, Di.; Li, Hao.; Liu, Qing-Rong.; Ding, Chang-Hua.; Chen, Bo.*; Hou, Xue-Long.* Palladium/N-heterocyclic carbene catalysed region and diastereoselective reaction of ketones with allyl reagents via inner-sphere mechanism. Nature Communications 2016, 7, 11806-11817. (IF = 12.353)\r
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7. Yu, Fei-Le.(#); Bai, Da-Chang.(#) ; Liu, Xiu-Yan.(#); Jiang, Yang-Jie.; Ding, Chang-Hua.*; Hou, Xue-Long.* Pd-Catalyzed Allylic Alkylation of gem-Alkyl, Aryl-Disubstituted Allyl Reagents with Ketones: Diastereoselective Construction of Vicinal Tertiary and Quaternary Carbon Centers. ACS Catal. 2018, 8, 3317–3321.(#: co-first authors, IF = 11.384)\r
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8. Bai, Da-Chang.;* Liu, Song.; Chen, Jun-Yan.; Yu, Yan-Jiang.; Wang, Man-Man.; Chang, Jun-Biao.; Lan., Yu.;* Li, Xing-Wei.* Mechanistic studies on nickel-catalyzed enantioselective [3 + 2] annulation for γ-butenolide synthesis via C–C activation of diarylcyclopropenones.Org. Chem. Front., 2021, 8, 3023-3031.\r
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9.Bai, Da-Chang.;* Chen, Jun-Yan.; Zheng, Bing-Bing.; Li, Xue-Yan.; Chang, Jun-Biao*. Catalytic [3+3] Annulation of β-Ketoethers and Cyclopropenones via C(sp3)-O/C-C Bond Cleavage under Transition-Metal Free Conditions.Chin. J. Chem. 2021, 39, 2769—2773\r
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10.Xu, Gui-Qing.; Chen, Qi.; Wu, Fen.; Bai, Da-Chang.;* Chang, Jun-Biao.;* Li, Xing-Wei.* Rh(III)-Catalyzed Chemodivergent Coupling of N‑Phenoxyacetamides and Alkylidenecyclopropanes via C−H Activation.Org. Lett. 2021, 23, 2927−2932.\r
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11.Bai, Da-Chang.; Jia, Qing-Qian.; Xu, Teng.; Zhang, Qiu-Qiu.; Wu, Fen.; Ma, Chao-Rui.; Liu, Bing-Xian.; Chang, Jun-Biao.*; Li, Xing-Wei.* Rhodium(III)-Catalyzed C−H Activation of Nitrones and Annulative Coupling with Nitroalkenes. J. Org. Chem. 2017, 82, 9877-9884.（IF= 4.849）\r
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12. Bai, Da-Chang.; Liu, Xiu-Yan.; Li, Hao.; Ding，Chang-Hua.*; Hou, Xue-Long.* Tandem Thorpe Reaction/Palladium Catalyzed Asymmetric Allylic Alkylation: Access to Chiral β-enaminonitriles with Excellent Enantioselectivity. Chemistry-An Asian Journal 2017, 12, 212-215.（IF = 3.692）\r
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13. Bai, Da-Chang.(#); Wang, Wan-Ying.(#); Ding, Chang-Hua.; Hou, Xue-Long*. Kinetic Resolution of Allyl Carbonates Using TMSCN as Nucleophile via Pd-Catalyzed Asymmetric Allylic Alkylation. Synlett. 2015, 26, 1510-1514.(#:co-first authors, IF = 2.419）\r
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14. Li, Xue-Yan.; Yu, Yan-Jiang.; Qi, Ruo-Bing.; Bai, Da-Chang*. Facile access to fluoroalkylated 2-aminopyridines by Cu-catalyzed [3 + 3] couplings of oxime esters with β-CF3 acrylonitrile. Tetrahedron Lett. 2020. 61, 151858-151861. (IF = 2.259)\r
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15.Cheng, Ruo-Shi.; Bai, Da-Chang.* Enantiodivergent Relay Coupling for Nickel-Catalyzed Stereoselective Functionalization of Cyclopropylzinc Reagents.Chin. J. Org. Chem. 2021, 41, 1746-1748.\r
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16. Dai, Hong-Xue.; Wu, Fen.; Bai, Da-Chang*. Recent Advances in Ni-Catalyzed C-C bond Activation Reactions. Chin. J. Org. Chem. 2020. 40. 1423-1436.\r
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17.Yang, Si-Qi.; Li, Xin.; Peng, Zhuo-Jin.; Yu, Wen-Yan.; Wang, Guang-Xu.; Jin, Ya-Lan.; Zheng, Bing-Bing.; Dai, Hong-Xue.; Bai, Da-Chang.* Synthesis of Pentafluoroethylated Pyridines via Cu-Catalyzed [3＋3]Cycloaddition Reaction of Oxime Acetates.Chin. J. Org. Chem. 2019, 39, 1623-1629.\r
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18.Huang, Shuai.; Tong, Fei-Fei.; Bai, Da-Chang.; Zhang, Gao-Peng.; Jiang, Yang-Jie.; Zhang, Bo.; Leng, Xue-Bing.; Guo, Yin-Long.; Wan, Xiao-Long.; Zhang, Xin-Gang.;* Ding, Chang-Hua.;* Hou, Xue-Long.* Regio- and enantioselective umpolung gemdifluoroallylation of hydrazones via palladium catalysis enabled by N-heterocyclic carbene ligand. Nat. Commun., 2021, 12, 6551.\r
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19.Tian, Miao-Miao.; Bai, Da-Chang.; Zheng, Guang-Fan.; Chang, Jun-Biao.; Li, Xing-Wei.* Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C−H Activation and Nucleophilic Cyclization. J. Am. Chem. Soc. 2019, 141, 9527−9532. \r
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20. Sun, Jia-Qiong.; Bai, Da-Chang.; Wang, Pei-Yuan.; Wang, Kuan.; Zheng, Guang-Fan.; Li, Xing-Wei. *Org. Lett. 2019, 21, 1789−1793. \r
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21.Wang, Man-Man.; Bai, Da-Chang.; Kong, Ling-Heng.; Liu, Bing-Xian.; Li, Xing-Wei.* Ag(I)-Catalyzed Nucleophilic Addition and Friedel-Crafts Alkylation between α-Oxo Ketene Dithioacetals and Propargylic Carbonates. Org. Lett. 2018, 20, 7775-7778. \r