个人简历

1993年于武汉大学获化学专业和细胞生物学专业学士学位；1999年1月于武汉大学获高分子化学和物理专业博士学位；1994年在北京大学医学部（原北京医科大学）药学院天然与仿生药物国家重点实验室从事高分子免疫佐剂的开放课题研究；1999年5月至2004年6月先后在约翰霍普金斯医学院新加坡生命医学中心（Johns Hopkins Singapore）、美国约翰霍普金斯大学医学院生物医学工程系从事博士后研究；任中国科学技术大学高分子科学与工程系教授，博士生导师，2006年7至8月，德国罗斯托克大学医学院访问教授；2006年12月至2016年5月任中国科学技术大学生命科学学院教授、博士生导师，合肥微尺度物质科学国家实验室研究员；2016年6月起任华南理工大学医学院、生命科学研究院及国家人体组织功能重建工程技术研究中心教授。

研究领域

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近期论文

Asplatin enhances drug efficacy by altering the cellular response\r
Author(s): Cheng, Q. Q.; Shi, H. D.; Wang, H. X.; et al.\r
Source: Metallomics Volume: 8 Issue: 7 Pages: 672-678 Published: 2016\r
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Facile Generation of Tumor-pH-Labile Linkage-Bridged Block Copolymers for Chemotherapeutic Delivery\r
Author(s): Sun, C. Y.; Liu, Y.; Du, J. Z.; et al.\r
Source: Angewandte Chemie-International Edition Volume: 55 Issue: 3 Pages: 1010-1014 Published: 2016\r
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Nanomedicine-mediated cancer stem cell therapy\r
Author(s): Shen, Song; Xia, Jin-Xing; Wang, Jun\r
Source: Biomaterials Volume: 74 Pages: 1-18 Published: 2016\r
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Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells\r
Author(s): Sun, R.; Shen, S.; Zhang, Y. J.; et al.\r
Source: Biomaterials Volume: 103 Pages: 44-55 Published: 2016\r
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Nanostructure-Based Theranostic Systems\r
Author(s): Wang, J.; Cui, H. G.\r
Source: Theranostics Volume: 6 Issue: 9 Pages: 1274-1276 Published: 2016\r
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Overcoming tumor resistance to cisplatin by cationic lipid-assisted prodrug nanoparticles\r
Author(s): Cao, Z. T.; Chen, Z. Y.; Sun, C. Y.; et al.\r
Source: Biomaterials Volume: 94 Pages: 9-19 Published: 2016\r
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Progress in the Development of Nanotheranostic Systems Honggang\r
Author(s): Cui, H. G.; Wang, J.\r
Source: Theranostics Volume: 6 Issue: 7 Pages: 915-917 Published: 2016\r
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Promoting tumor penetration of nanoparticles for cancer stem cell therapy by TGF-beta signaling pathway inhibition\r
Author(s): Zuo, Z. Q.; Chen, K. G.; Yu, X. Y.; et al.\r
Source: Biomaterials Volume: 82 Pages: 48-59 Published: 2016\r
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Restoring anti-tumor functions of T cells via nanoparticle-mediated immune checkpoint modulation\r
Author(s): Li, S. Y.; Liu, Y.; Xu, C. F.; et al.\r
Source: Journal of Controlled Release Volume: 231 Pages: 17-28 Published: 2016\r
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Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration\r
Author(s): Li, H. J.; Du, J. Z.; Liu, J.; et al.\r
Source: ACS Nano Volume: 10 Issue: 7 Pages: 6753-6761 Published: 2016\r
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Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy\r
Author(s): Li, Hong-Jun; Du, Jin-Zhi; Du, Xiao-Jiao; et al.\r
Source: Proceedings of the National Academy of Sciences of the United States of America Volume: 113 Issue: 15 Pages: 4164-4169 Published: 2016\r
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Surface charge critically affects tumor penetration and therapeutic efficacy of cancer nanomedicines\r
Author(s): Wang, H. X.; Zuo, Z. Q.; Du, J. Z.; et al.\r
Source: Nano Today Volume: 11 Issue: 2 Pages: 133-144 Published: 2016\r
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Three-Dimensional Nanofiber Hybrid Scaffold Directs and Enhances Axonal Regeneration after Spinal Cord Injury\r
Author(s): Milbreta, U.; Nguyen, L. H.; Diao, H. J.; et al.\r
Source: Acs Biomaterials Science & Engineering Volume: 2 Issue: 8 Pages: 1319-1329 Published: 2016\r
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Tumor acidity-sensitive linkage-bridged block copolymer for therapeutic siRNA delivery\r
Author(s): Xu, Cong-Fei; Zhang, Hou-Bing; Sun, Chun-Yang; et al.\r
Source: Biomaterials Volume: 88 Pages: 48-59 Published: 2016\r
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A block copolymer of zwitterionic polyphosphoester and polylactic acid for drug delivery\r
Author(s): Sun, Rong; Du, Xiao-Jiao; Sun, Chun-Yang; et al.\r
Source: Biomaterials Science Volume: 3 Issue: 7 Pages: 1105-1113 Published: 2015\r
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Biocompatible Conjugated Polymer Nanoparticles for Efficient Photothermal Tumor Therapy\r
Author(s): Geng, Junlong; Sun, Chunyang; Liu, Jie; et al.\r
Source: Small Volume: 11 Issue: 13 Pages: 1603-1610 Published: 2015\r
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Co-delivery of all-trans-retinoic acid and doxorubicin for cancer therapy with synergistic inhibition of cancer stem cells\r
Author(s): Sun, Rong; Liu, Yang; Li, Shi-Yong; et al.\r
Source: Biomaterials Volume: 37 Pages: 405-414 Published: 2015\r
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Co-delivery of platinum drug and siNotch1 with micelleplex for enhanced hepatocellular carcinoma therapy\r
Author(s): Shen, S.; Sun, C. Y.; Du, X. J.; et al.\r
Source: Biomaterials Volume: 70 Pages: 71-83 Published: 2015\r
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Combination therapy with epigenetic-targeted and chemotherapeutic drugs delivered by nanoparticles to enhance the chemotherapy response and overcome resistance by breast cancer stem cells\r
Author(s): Li, Shi-Yong; Sun, Rong; Wang, Hong-Xia; et al.\r
Source: Journal of Controlled Release Volume: 205 Pages: 7-14 Published: 2015\r
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Delivery of bortezomib with nanoparticles for basal-like triple-negative breast cancer therapy\r
Author(s): Shen, Song; Du, Xiao-Jiao; Liu, Jing; et al.\r
Source: Journal of Controlled Release Volume: 208 Pages: 14-24 Published: 2015