个人简历

2016-至今，华南理工大学博士生导师 2004-2016，中国科学技术大学“百人计划”特聘教授 1998-2004，美国及中国数家生物技术公司担任研发总监 1995-1998，美国斯坦福大学高级研究员 1993-1995，厦门大学副教授 1990-1993，新加坡国立大学研究员 1988-1990，美国斯坦福大学博士后研究员 1982-1988，美国洛衫矶加洲大学攻读博士学位 1978-1982，厦门大学完成学士学位

研究领域

1. 纳米材料引起的细胞自噬等特殊生物学效应；2. 工程化纳米颗粒在肿瘤免疫治疗中的应用；3. 功能短肽介导的药物输运

近期论文

1. Chen YP, Shen YY, Guo X, Zhang CS, Yang WJ, Ma ML, Liu S, Zhang MB, Wen LP*. Transdermal protein delivery by a co-administered peptide identified via phage display. Nature Biotechnology 24：455-50 (2006). 2. Zhang YJ, Zheng F, Yang TL, Zhou W, Liu Y, Man N, Zhang L, Jin N, Dou QQ, Zhang Y, Li ZQ & Wen LP*.Tuning the autophagy-inducing activity of lanthanide-based nanocrystals through specific surface-coating peptides. Nature Materials. 11, 817–826 (2012) 3. Zhang Q, Yang WJ, Man N, Zheng F, Shen YY, Sun KJ, Li Y and Wen LP*. Autophagy-mediated chemosensitization in cancer cells by fullerene C60 nanocrystal. Autophagy 5(8)：1107-17 (2009). 4. Yu L, Lu Y, Man N, Yu SH, Wen LP*. Rare earth oxide nanocrystals induce autophagy in HeLa cells. Small. 5(24):2784-87 (2009). 5. Man N,Yu L, Yu SH and Wen LP* .Rare earth oxide nanocrystals as a new class of autophagy inducers. Autophagy 6，2：310-11(2010). 6. Man N, Chen Y, Zheng F, Zhou W and Wen LP*. Induction of Genuine Autophagy by Cationic Lipids In Mammalian Cells. Autophagy 6，4：449-54 (2010). 7. Lu Y, Zhang L, Li J, Su YD, Liu Y, Xu YJ, Dong L, Gao HL, Lin J, Man N, Wei PF, Xu WP, Yu SH* and Wen LP*. MnO nanocrystals: A platform for integration of MRI and genuine autophagy induction for chemotherapy. Adv. Funct. Mater., 23: 1534–1546. (2012). 8. Dong L, Liu Y, Lu Y, Zhang L, Man N, Cao L, Ma K, An D, Lin J, Xu YJ, Xu WP, Wu WB, Yu SH* and Wen LP*. Tuning Magnetic Property and Autophagic Response for Self-Assembled Ni-Co Alloy Nanocrystals. Adv. Funct. Mater. 23: 5930–5940. (2013) 9. Lin J, Huang Z, Wu H, Zhou W, Jin P, Wei P, Zhang Y, Zheng F, Zhang J, Xu J, Hu Y, Wang Y, Li Y, Gu N, Wen LP*.Inhibition of autophagy enhances the anticancer activity of silver nanoparticles. Autophagy. 2;10(11):2006-20. (2014) 10. Miao YY, Xu J, Shen Y, Chen L, Bian YP, Hu Y, Zhou W, Zheng F, Man N, Shen YY, Zhang YJ, Wang M*, and Wen LP*. Nanoparticle as Signaling Protein Mimic: Robust Structural and Functional Modulation of CaMKII upon Specific Binding to Fullerene C60 Nanocrystals. ACS Nano. 8 (6), pp 6131–6144. (2014)