陈柱
近期热点
资料介绍
个人简历
博士毕业与东南大学生物医学工程专业,目前在湖南工业大学从事教学科研工作,硕士生导师,主持国家自然青年科学基金、湖南省自然青年科学基金、中国博士后基金一等资助与横向合作课题多项;作为骨干参与国家重点研发项目、国家重大科研仪器研制项目、湖南省重点研发计划等多项。在SCI期刊Cell Proliferation(IF=5.753)、Chinese Chemical Letters(IF=4.6324)、Journal of Biomedical Nanotechnology(IF=4.483)等发表高水平论文20余篇,其中入选ESI全球TOP 0.1% 1篇和1%论文2篇。申请国家专利15余项,授权9项,授权软件著作权2项。2017年获得株洲市科技创新奖1项。所研制的便携式致病菌核酸检测仪,先后获得企业约50万元经费支持,完成专利成果转让(专利号: 201921084249.X)及负责产品转化与生产。主持参与项目1. 国家重点研发计划-政府间国际科技创新合作专项,2021YFE0191400,精神分裂症超高危人群转化趋势的预测指标及机制研究,2021/07-2024/06,386万,在研,参与2. 横向课题,便携式致病菌核酸检测仪研制,2020/01-2021/05,50万,结题,主持3. 国家青年科学基金,61901168,基于磁分离与投射-散射式浊度法的致病菌现场核酸定量检测一体化研究,2020/01-2022/12,27.5万元,在研,主持 4. 湖南省自然科学基金,2019JJ50122,基于全封闭卡盒的全自动单纯疱疹病毒核酸分型检测系统研究,2019.09-2020.12,5万元,已结题,主持5. 第63批中国博士后科学基金面上资助一等资助,2018M630498,基于磁分离和RPA技术的一体化LM快速诊断系统研究,8万元,在研,主持6. 湖南省教育厅一般项目, 17C0486, 基于磁分离的快速核酸提取系统的研制,2017.09-2020.12,1万元,已结题,主持7. 国家自然科学基金项目,61971187,基于磁性纳米颗粒与全自动卡盒的个体化免疫租库信息高通量获取方法研究,2020/01-2024/12,59万元,已结题,参与(3)8. 湖南省优秀青年项目,18B299,基于通用滚环扩增技术的快速可视化高通量核酸分子检测方法研究,2019.01-2021.12,4万元,在研,参与(2)9. 湖南省重点研发计划项目,2017SK2174,基于DNA突变和甲基化检测的封闭卡盒式无创结肠癌筛查系统研究,2018.01-2019.12,20万元,已结题,参与(2)10. 国家重大科研仪器研制项目,61527806,基于核酸适配体识别的肿瘤细胞新型标志物高效筛选仪的研制,2016/01-2020/12,606万元,已结题,参与11. 国家青年科学基金,61701176,院内艰难梭菌感染(CDI)快速一体化检测技术的研究,2018/01-2020/01,25万元,在研,参与12. \研究领域
是核酸提取、扩增与检测一体化/小型化系统研制,并与企业合作负责便携式致病菌核酸检测系统与全自动化核酸提取系统开发"长期从事分子检测方法与技术研发与转化"近期论文
1. Y. Y Xu., T. Wang., Z. Chen*., L. Jin., Z. Z. Wu., J. Q. Yan., X. N. Zhao., L. Cai., Y. Deng., Y. Guo*., S. Li*., and N. Y. He, 2021. The point-of-care-testing of nucleic acids by chip, cartridge and paper sensors[J], Chinese Chemical Letters, DOI: 10.1016/j.cclet.2021.06.025 (IF=4.6324)2. Z. Y. He., Z. R. Tong., B. Y. Tan., X. L. He., T. Zhang., Y. Guo., L. Jin., N. Y. He., S. Li., and Zhu Chen*, 2021. Rapid detection of DNA methylation with a novel real-time fluorescence recombinase-aided amplification assay. Journal of Biomedical Nanotechnology, DOI:10.1166/jbn.2021.3111 (IF=4.483)3. Y. L. Fang., H. R. Liu., Y. Wang., X. Y. Su., L. Jin., Y. Q. Wu., Y. Deng., S. Li., Z. Chen*., H. Chen*., and N. Y. He*, 2021. Fast and Accurate Control Strategy for Portable Nucleic Acid Detection (PNAD) System Based on Magnetic Nanoparticles. Journal of Biomedical Nanotechnology, 17(3), pp.407-415 (IF=4.483)4. Z. Chen., C. G. Xiao., H. H. Qiu., X. X. Tan., L. Jin., Y. He., Y. Guo*., and N. Y. He*, 2020. Recent Advances of Artificial Intelligence in Cardiovascular Disease. Journal of Biomedical Nanotechnology, 16(8), pp.1065-1081 (IF=4.483)5. H. Chen*., Z. Q. Xiao., Z. Chu*., L. Jin., S. Li., Y. Deng., Z. Chen*., G. H. Hu., Y. Q. Wu*., and N. Y. He*., Novel Detection of Norovirus and Double Clostridium difficile in a Closed Cartridge System6. G. J. Yang., H. Huang., Z. Q. Xiao., C. X. Zhang., W. F. Guo., T. T. Ma., L. Ma., Z. Chen*., and Y. Deng*, 2020. A Novel Strategy for Liquid Exfoliation of Ultrathin Black Phosphorus Nanosheets. Journal of Biomedical Nanotechnology, 16(4), pp.548-552 (IF=4.483)7. Y. P. Huang., C. Wang., H. Zhu., Z. L. Wang., H. Chen.,S. Li., T. H. Liu., N. Y. He*., and Z. Chen*, 2020. Design and Implementation of a High-Throughput Vibrating Module for Nucleic Acid Detection System. Journal of Nanoscience and Nanotechnology, 20(4), pp.2165-21708. C. Wang., F. Meng., Y. P. Huang., N. Y. He*., and Z. Chen*, 2020. Design and Implementation of Polymerase Chain Reaction Device for Aptamers Selection of Tumor Cells. Journal of Nanoscience and Nanotechnology, 20(3), pp.1332-13409. Z. He., Z. Chen*., M. Tan., S. Elingarami., Y. Liu., T. Li., Y. Deng., N. He., S. Li*., J. Fu*., and W. Li, 2020. A review on methods for diagnosis of breast cancer cells and tissues. Cell Proliferation, 53(7), e12822 (IF=5.753)10. Y. Huang., C. Wang., H. Zhu., Z. Wang., H. Chen., S. Li., T. Liu., N. He., and Z. Chen*, 2020. Design and Implementation of a High-Throughput Vibrating Module for Nucleic Acid Detection System. Journal of Nanoscience and Nanotechnology, 20(4), pp.2165-217011. Z. Chen*., C. Xiao., M. Tang., Y. Xu., Z. He., Y. Hou., X. Luo., W. Li., Y. Deng., and S. Li, 2019. Advances in Fully Automated Nucleic Acid Extraction System Based on Magnetic Nanobeads. Nanoscience and Nanotechnology Letters, 11(12), pp.1633-164312. Z. He., C. Tang., X. Chen., H. Liu., G. Yang., Z. Xiao., W. Li., Y. Deng., L. Jin., H. Chen., Z. Chen*., and S. Li, 2019. Based on magnetic beads to develop the kit for extraction of high-quality cell-free DNA from blood of breast cancer. Materials Express, 9(8), pp.956-96113. T. Zhao., J. Yu., Z. He., N. He., M. Dong., Z. Chen*., and H. Chen*, 2019. Facile Fabrication of Nano-MIL-101(Cr) with Enhancement of Catalytic Activity in Oxidation of Indene. Nanoscience and Nanotechnology Letters, 11(2), pp.229-23314. Z. Chen., T. Yang., H. Yang., T. Li., L. Nie., X. Mou., Y. Deng., N. He*., Z. Li*., L. Wang*., and S. Li*, 2018. A Portable Multi-Channel Turbidity System for Rapid Detection of Pathogens by Loop-Mediated Isothermal Amplification. Journal of Biomedical Nanotechnology, 14(1), pp.198-205 (ESI高被引和热点)15. Z. Chen., H. Yang., J. Peng., Y. Fang., H. Dong., H. Chen., J. Yu., L. Nie., Y. Deng., S. Li., H. Liu., L. Wang*., and N. He*, 2018. Highly Precise and Fast Polymerase Chain Reaction Thermal Cycling Module with a Novel Integrated Temperature Control Strategy. Nanoscience and Nanotechnology Letters, 10(1), pp.23-3116. Z. Chen., Y. Wu., M. Kang., N. He*., S. Wan*., E. Su., and L. Wang*, 2018. Research on Automated Nucleic Acid Extraction Instrument Based on Magnetic Nanoparticles Separation. Nanoscience and Nanotechnology Letters, 10(1), pp.60-68 (ESI高被引)17. T. Yang., C. Wu., Z. Li., Y. Chen., H. Chen., H. Gao., M. Liu., N. He*., H. Liu., B. Liu., Z. Chen*., S. Elingarami., and M. A. Shah, 2017. Design and Application of a Portable Multi-Channel Turbidimeter by Loop-Mediated Isothermal Amplification. Nanoscience and Nanotechnology Letters, 9(12), pp.1926-193318. J. Peng., M. Li., Z. Chen*., H. Liu., Z. Wang., E. Su., S. Elingarami., M. A. Shah., and N. He, 2017. A Piecewise Fuzzy Proportional Integral Derivative Control for Polymerase Chain Reaction Thermal Cycling. Nanoscience and Nanotechnology Letters, 9(11), pp.1775-178019. Z. Chen., S. Wan*., C. Wang., H. Chen., Y. Wu., L. Nie., B. Liu., H. Zhu., and N. He*, 2016. Temperature and Motion Modules of Automatic Nucleic Acid Extractor. Journal of Nanoscience and Nanotechnology, 16(7), pp.6872-687720. Z. Chen., Y. Wu., H. Chen.,X. Mou., Z. Chen., Y. Deng., B. Liu., and S. Wan*, 2016. Design and Application of Automatic and Rapid Nucleic Acid Extractor Using Magnetic Nanoparticles. Journal of Nanoscience and Nanotechnology, 16(7), pp.6998-700421. 陈柱., 贺子瑜., 何农跃., 邓燕., 李松, 2019. LAMP实时浊度法快速检测大肠杆菌方法的建立与优化研究.包装学报. 11(02), pp.52-5822. 陈柱., 聂立波., 常浩, 2012. 基于AVR单片机的温度测量与控制系统设计. 湖南工业大学学报. 26(03), pp.76-8123. 陈柱., 聂立波., 常浩, 2011. 石英晶体微天平的研究进展及应用. 分析仪器. (04), pp.18-22 相关热点
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