个人简历

1990、1997年分别毕业于白求恩医科大学、同济医科大学，分别获得医学学士、医学硕士学位，2000年毕业于华中科技大学同济医学院，获得医学博士学位。2000-2005年在美国佛罗里达大学医学院病理学、免疫学和实验医学系从事博士后研究工作，2005-2009年任美国佛罗里达大学医学院的Assistant Scientist。自2008年起任湖南大学教授，2010起兼任湖南省肿瘤医院（现中南大学湘雅医学院附属肿瘤医院）教授，2009年教育部新世纪优秀人才支持计划获得者。2014年参加国家杰出青年科学基金答辩。教育背景 1990年毕业于白求恩医科大学，获得医学学士 1997年毕业于同济医科大学，医学硕士学位 2000年毕业于华中科技大学同济医学院，获得医学博士学位 学术兼职 兼任湖南省肿瘤医院（现中南大学湘雅医学院附属肿瘤医院）教授 Frontier in Immunology、Annals of Infectious Disease and Epidemiology等期刊编委 Oncotarget、FEBS Letter、Laboratory Investigation、Journal of Medical Virology、PLoS ONE、Virology Journal等期刊审稿人

研究领域

主要从事肿瘤学、微生物学、免疫学、分子生物学和细胞生物学领域的教学和科研工作。具体研究内容包括肿瘤细胞信号传导与免疫调节机制、病毒与宿主的相互作用、肿瘤细胞与病毒的免疫逃逸机制，以及恶性肿瘤和肝炎的生物治疗靶向药物、肿瘤免疫治疗药物与疫苗的研发。

近期论文

1. Xu C, Yang D, Mei L, Lu B, Chen L, Li Q, Zhu H, Wang TH.Encapsulating gold nanoparticles or nanorods in grapheme oxide shell as a novel gene vector. ACS Appl Mater Interfaces 2013; 5:2715-2724. 2. Yang D, Liu N, Zuo C, Lei S, Wu X, Zhou F, Liu C, Zhu H. Innate immune response of primary human hepatocytes with hepatitis C viralinfection.PLoS One 2011; 6(11):e27552 3. Meng L, Yang L, Zhao X, Zhang L, Zhu H, Liu C, Tan W. Targeted delivery of chemotherapy agents using a liver cancer-specific aptamer. PLoS One 2012; 7(4):e33434 4. Tan W, Wang H, Chen Y, Zhang X, Zhu H, Yang C, Yang R, Liu C. Molecular aptamers for drug delivery. Trends Biotechnol 2011; 29:634-640 5. Eksioglu EA, Zhu H, Bayouth L, Bess J, Liu HY, Nelson DR, Liu C. Characterization of HCV interactions with Toll-like receptors and RIG-I in liver cells. PLoS One 2011; 6(6):e21186 6. Zhao X, Cao M, Liu JJ, Zhu H, Nelson DR, Liu C. Reactive oxygen species is essential for cycloheximide to sensitize lexatumumab-induced apoptosis in hepatocellular carcinoma cells. PLoS One 2011; 6(2):e16966 7. Yao L, Dong H, Zhu H, Nelson DR, Liu C, Lambiase L, Li X. Identification of IFITM3 gene as an inhibitors of hepatitis C viral translation in a stable STAT1 cell line. J Viral Hepat 2011; 18:e523-e529 8. Eksioglu EA, Bess J, Zhu H, Xu Y, Dong H, Elyar J, Nelson DR, Liu C. Hepatitis C virus modulates human monocyte-derived dendritic cells. J Viral Hepat 2010; 17:757-769 9. Eksioglu EA, Bess J, Jones G, Dettloff J, Dangmeon P, Dong HJ, Zhu H, Firpi R, Xu Y, Nelson DR, Liu C. Characterization of anti-HCV antibodies in IL-10 treated patients. Viral Immunology 2010;23:359-368 10. Zhu H, Elyar J, Foss R, Hemming A, Hall E, Lecluyse EL, Liu C. Primary human hepatocyte culture for HCV study. Methods Mol Biol, 2009 510:373-382 11. Kenworthy R, Lambert D, Yang F, Wang N, Chen Z, Zhu H, Zhu F, Liu C, Li K, Tang H. Short-hairpin RNAs delivered by lentiviral vector transduction trigger RIG-I-mediated IFN activation. Nucleic Acids Res.2009;37:6587-6599 12. Wu H, Zhu H, Zhuang J, Liu C, Cao YC. Water-soluble nanocrystals through dual-interaction ligands. Angew Chem Int Edit. 2008; 47:3730-34 13. Li C, Long Y, Liu B, Xiang D, Zhu H. Real-time monitoring uracil excision using uracil-containing molecular beacons. Anal Chim Acta 2014; 819:71-77. 14. Butler SL, Dong H, Cardona D, Jia M, Zheng R, Zhu H, Crawford JM, Liu C. The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1. Lab Invest 2008; 88:78-88 15. Zhu H, Dong H, Eksioglu E, Hemming A, Cao M, Crawford CM, Nelson DR, Liu C. Hepatitis C virus triggers apoptosis of a newly developed hepatoma cell line through antiviral defense system. Gastroenterology 2007; 133:1649-1659 16. Liu C, Zhu H, Subramanian MG, Moore PA, Xu Y, Nelson DR. Anti-hepatitis C virus activity of albinterferon alfa-2b in cell culture. Hepatology Research. 2007; 37:941-947 17. Cao M, Cabrera R, Xu Y, Firpi R, Zhu H, Liu C, Nelson DR. Hepatocellular carcinoma cell supernatants increase expansion and function of CD4(+)CD25(+) regulatory T cells. Lab Invest. 2007, 87:582-590 18. *Firpi RJ, Zhu H, Morelli G, Abdelmalek MF, Reed AI, Liu C, Nelson DR. Cyclosporine suppresses hepatitis C virus in vitro and increase the chance of sustained virological response after liver transplantation. Liver Transplantation 2006, 12:51-57 (see Editorial on Page 19-21) 19. Zhu H, Butera M, Nelson DR and Liu C. Novel type I Interferon IL-28A suppresses hepatitis C viral RNA replication. Virology J 2005, 2:80