张璨
近期热点
资料介绍
个人简历
2012年毕业于湖南师范大学,获得生物科学学士学位; 同年保送至浙江大学基础医学院直接攻博,2017年获得干细胞和再生医学专业博士学位。2017年7月进入湖南大学生物学院生物纳米与组织工程学研究所任助理教授。获得第十七届国际肌腱韧带会议最佳研究者奖。教育背景 2012年毕业于湖南师范大学,获得生物科学学士学位; 2012年保送至浙江大学基础医学院直接攻博,2017年获得干细胞和再生医学专业博士学位 工作履历 2017年7月进入湖南大学生物学院生物纳米与组织工程学研究所任助理教授研究领域
从事肌腱组织损伤再生修复及肌腱病治疗的基础研究,研究方向为肌腱组织工程;表观遗传与干细胞定向分化;细胞与细胞外基质相互作用。研究兴趣主要包括:1. 具有生物活性的肌腱组织工程支架开发;2. 肌腱表型维持和分化的小分子筛选和功能验证;3. 大数据时代的肌腱组织发育和肌腱病发生的分析。近期论文
1. Can Zhang, Erchen Zhang, Long Yang, Wenjing Tu, Junxin Lin, Chunhui Yuan, Varisara Bunpetch, Xiao Chen*, Hongwei Ouyang*. Histone Deacetylase Inhibitor Treated Cell Sheet from Mouse Tendon Stem/Progenitor Cells Promotes Tendon Repair. Biomaterials, 172, 66-82. 2018 2. Can Zhang, Xianliu Wang, Erchen Zhang, Long Yang, Huihua Yuan, Wenjing Tu, Huilan Zhang, Zi Yin, Weiliang Shen, Xiao Chen*, Yanzhong Zhang*, Hongwei Ouyang*. An Epigenetic Bioactive Composite Scaffold with Well-aligned Nanofibers for Functional Tendon Tissue Engineering. Acta Biomaterialia 66, 141-156. 2018 3. Can Zhang, Huihua Yuan, Liu Huanhuan, Chen Xiao, Lu Ping, Zhu Ting, Yang Long, Yin Zi, Boon Chin Heng, Zhang Yanzhong*, Ouyang HongWei*. Well-aligned Chitosan-based Ultrafine Fibers Committed Teno-lineage Differentiation of Human Induced Pluripotent Stem Cells for Achilles Tendon Regeneration. Biomaterials 53, 716-730. 2015 4. Huanhuan Liu, Can Zhang, Shouan Zhu, Ping Lu, Ting Zhu, Xiaolan Gong, Ziwang Zhang, Jiajie Hu, Zi Yin, Boon Chin Heng, Xiao Chen*, Hongwei Ouyang*. Mohawk Promotes The Tenogenesis of Mesenchymal Stem Cells Through Activation of The TGFβ Signaling Pathway, Stem Cells 33, 443-455. 2015 5. Mingying Yang#*, Yajun Shuai#, Can Zhang#, Yuyin Chen, Liangjun Zhu, Chuanbin Mao*, Hongwei Ouyang. Biomimetic Nucleation of Hydroxyapatite Crystals Mediated by Antheraea pernyi Silk Sericin Promotes Osteogenic Differentiation of Human Bone Marrow Derived Mesenchymal Stem Cells. Biomacromolecules 15, 1185-1193. 2014 6. Huanhuan Liu, Shouan Zhu, Can Zhang, Ping Lu, Jiajie Hu, Yue Ma, Xiao Chen, Hongwei Ouyang*. Crucial Transcription Factors in Tendon Development and Differentiation: Their Potential for Tendon Regeneration. Cell Tissue Research 356, 287-298. 2014 7. Huanhuan Liu, Hongju Peng, Yan Wu, Can Zhang, Youzhi Cai, Guowei Xu, Qin Li, Xiao Chen, Junfeng Ji, Yanzhong Zhang*, Hongwei Ouyang*. The Promotion of Bone Regeneration by Nanofibrous Hydroxyapatite/Chitosan Scaffolds by Effects on Integrin-BMP/Smad Signaling Pathway in BMSCs. Biomaterials 34, 4404-4417. 2013 相关热点
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