个人简历

游常军，湖南大学化学化工学院、化学生物传感与计量学国家重点实验室、生物大分子化学生物学湖南省重点实验室、湖南大学分子科学与分子医学实验室（MBL）教授、博士生导师，化学修饰与分子毒理课题组负责人，Chemical Society Reviews、Journal of the American Chemical Society、 Analytical Chemistry、Chemical Communications、Chemical Research in Toxicology、 Environmental and Molecular Mutagenesis以及Science China Chemistry等国内外学术期刊审稿人。博士毕业于华中农业大学生命科学技术学院，获得理学博士学位，随后进入美国加州大学河滨分校化学系开展博士后研究工作。

研究领域

课题组目前的研究方向为生命分析化学和化学生物学，主要涉及生物质谱分析、核酸化学修饰、分子毒理学及纳米生物医学等方面的相关研究。

近期论文

1. You, C., Dai, X., and Wang, Y. Position-dependent effects of regioisomeric methylated adenine and guanine ribonucleosides on translation. Nucleic Acids Research, 2017, 45: 9059-9067. 2. You, C., and Wang, Y. Mass spectrometry-based quantitative strategies for assessing the biological consequences and repair of DNA adducts. Accounts of Chemical Research, 2016, 49: 205-213. 3. You, C., Wang, P., Nay, S., Wang, J., Dai, X., O’Connor, T., and Wang, Y. Roles of AAG, ALKBH2 and ALKBH3 in the repair of carboxymethylated and ethylated thymidine lesions. ACS Chemical Biology, 2016, 11: 1332-1338. 4. You, C., and Wang, Y. Quantitative measurement of transcriptional inhibition and mutagenesis induced by site-specific DNA lesions in vitro and in vivo. Nature Protocols, 2015, 10: 1389-1406. 5. You, C., Wang, J., Dai, X., and Wang, Y. Transcriptional inhibition and mutagenesis induced by N-nitroso compound-derived carboxymethylated thymidine adducts in DNA. Nucleic Acids Research, 2015, 43: 1012-1018. 6. You, C., Wang, P., Dai, X., and Wang, Y. Transcriptional bypass of regioisomeric ethylated thymidine lesions by T7 RNA polymerase and human RNA polymerase II. Nucleic Acids Research, 2014, 42:13706-13713. 7. You, C., Swanson, A., Dai, X., Yuan, B., Wang, J., and Wang Y. Translesion Synthesis of 8,5'-Cyclopurine-2'-deoxynucleosides by DNA Polymerases η, ι, and ζ. Journal of Biological Chemistry, 2013, 288, 28548-28556. 8. You, C., Dai, X., Yuan, B., and Wang, Y. Effects of 6-thioguanine and S6-methylthioguanine on transcription in vitro and in human Cells. Journal of Biological Chemistry, 2012, 287:40915-23. 9. You, C., Dai, X., Yuan, B., Wang, J., Wang, J., Brooks, P., Niedernhofer, L., and Wang, Y. A quantitative assay for assessing the effects of DNA lesions on transcription. Nature Chemical Biology, 2012, 8, 817-822.