个人简历

教育背景 2001-2005华中农业大学生物技术专业本科； 2005-2008华中农业大学预防兽医学硕士； 2008-2011中国科学院武汉病毒研究所生化与分子生物学博士； 2010法国巴斯德研究所中法联合培养博士生项目。 工作履历 2016.6至今任湖南大学生物学院教授、博士生导师； 2013.9-2016.5任国科学院武汉病毒研究所副研究员； 2012.1-2013.8任国科学院武汉病毒研究所助理研究员。

研究领域

动物新型病毒病原发现与鉴定、病毒生物信息学、重要病毒病原如冠状病毒、汉坦病毒等的种间传播、感染和致病机制等。

近期论文

1. Ge XY, Li JL, Yang XL, Chmura AA, Zhu G, Epstein JH, Mazet JK, Hu B, Zhang W, Peng C, Zhang YJ, Luo CM, Tan B, Wang N, Zhu Y, Crameri G, Zhang SY, Wang LF, Daszak P, Shi ZL. Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor. Nature. 2013 Nov 28;503(7477):535-8. doi: 10.1038/nature12711. 2. Ge XY, Yang WH, Zhou JH, Li B, Zhang W, Shi ZL, Zhang YZ. Detection of alpha- and betacoronaviruses in rodents from Yunnan, China. Virol J. 2017 May 26;14(1):98. 3. Ge XY, Wang N, Zhang W, Hu B, Li B, Zhang YZ, Zhou JH, Luo CM, Yang XL, Wu LJ, Wang B, Zhang Y, Li ZX, Shi ZL. Coexistence of multiple coronaviruses in several bat colonies in an abandoned mineshaft. Virol Sin. 2016 Feb;31(1):31-40. 4. Ge XY, Yang WH, Pan H, Zhou JH, Han X, Zhu GJ, Desmond JS, Daszak P, Shi ZL, Zhang YZ. Fugong virus, a novel hantavirus harbored by the small oriental vole (Eothenomys eleusis) in China. Virol J. 2016 Feb 16;13:27. doi:10.1186/s12985-016-0483-9. Erratum in: Virol J. 2016;13(1):75. 5. Xing-Yi Ge, Ben Hu, and Zheng-Li. Chapter 5: Bat coronaviruses, p127-148. Bats and Viruses: From Pathogen Discovery to Host Genomics. Lin-fa Wang, 2015, Wiley-Blackwell. ISBN: 9781118818732. Published Online: 26 JUN 2015, DOI: 10.1002/9781118818824.ch5. 6. Ge X, Wu Y, Wang M, Wang J, Wu L, Yang X, Zhang Y, Shi Z. Viral metagenomics analysis of planktonic viruses in East Lake, Wuhan, China. Virol Sin. 2013 Oct;28(5):280-90. 7. Ge X, Li Y, Yang X, Zhang H, Zhou P, Zhang Y, Shi Z. Metagenomic analysis of viruses from bat fecal samples reveals many novel viruses in insectivorous bats in China. J Virol. 2012 Apr;86(8):4620-30. 8. Ge X, Rameix-Welti MA, Gault E, Chase G, dos Santos Afonso E, Picard D, Schwemmle M, Naffakh N. Influenza virus infection induces the nuclear relocalization of the Hsp90 co-chaperone p23 and inhibits the glucocorticoid receptor response. PLoS One. 2011;6(8):e23368. doi: 10.1371/journal.pone.0023368. 9. Ge X, Li J, Peng C, Wu L, Yang X, Wu Y, Zhang Y, Shi Z. Genetic diversity of novel circular ssDNA viruses in bats in China. J Gen Virol. 2011 Nov;92(Pt 11):2646-53. 10.Li TT, Li JY, Huang T, Ge XY. Complete Genome Sequence of a Novel Strain of Infectious Bronchitis Virus, Isolated from Chickens in China in 2016. Genome Announc. 2017 Nov 9;5(45). pii: e01277-17. doi: 10.1128/genomeA.01277-17. 11.Zeng Z, Li TT, Jin X, Peng FH, Song NH, Peng GQ, Ge XY. Coexistence of multiple genotypes of porcine epidemic diarrhea virus with novel mutant S genes in the Hubei Province of China in 2016. Virol Sin. 2017 Aug;32(4):298-306. 12.Wang N, Ruan Z, Wan Y, Wang B, Zhang SH, Ge XY. Identification of a novel strain of influenza A (H9N2) virus in chicken. Virol Sin. 2015 Aug;30(4):309-12. doi: 10.1007/s12250-015-3616-1. PubMed PMID: 26242377. 13.Zhang Z, Zhu Z, Chen W, Cai Z, Xu B, Tan Z, Wu A, Ge X, Guo X, Tan Z, Xia Z, Zhu H, Jiang T, Peng Y. Cell membrane proteins with high N-glycosylation, high expression, and multiple interaction partners are preferred by mammalian viruses as receptors. Bioinformatics. 2018 Aug 9. doi: 10.1093/bioinformatics/bty694. 14.Zhu Z, Zhang Z, Chen W, Cai Z, Ge X, Zhu H, Jiang T, Tan W, Peng Y. Predicting the receptor-binding domain usage of the coronavirus based on kmer frequency on spike protein. Infect Genet Evol. 2018 Jul;61:183-184. 15.Hu B, Zeng LP, Yang XL, Ge XY, Zhang W, Li B, Xie JZ, Shen XR, Zhang YZ, Wang N, Luo DS, Zheng XS, Wang MN, Daszak P, Wang LF, Cui J, Shi ZL. Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus. PLoS Pathog. 2017 Nov 30;13(11):e1006698. 16.Zeng LP, Ge XY, Peng C, Tai W, Jiang S, Du L, Shi ZL. Cross-neutralization of SARS coronavirus-specific antibodies against bat SARS-like coronaviruses. Sci China Life Sci. 2017 Dec;60(12):1399-1402. 17.Zhu Y, Mao C, Ge X, Wang Z, Lu P, Zhang Y, Chen S, Hu Y. Characterization of a Minimal Type of Promoter Containing the -10 Element and a Guanine at the -14 or -13 Position in Mycobacteria. J Bacteriol. 2017 Oct 3;199(21). pii: e00385-17. 18.Tan B, Yang XL, Ge XY, Peng C, Liu HZ, Zhang YZ, Zhang LB, Shi ZL. Novel bat adenoviruses with low G+C content shed new light on the evolution of adenoviruses. J Gen Virol. 2017 Apr;98(4):739-748. doi: 10.1099/jgv.0.000739. PubMed PMID: 28475035. 19.Waruhiu C, Ommeh S, Obanda V, Agwanda B, Gakuya F, Ge XY, Yang XL, Wu LJ, Zohaib A, Hu B, Shi ZL. Molecular detection of viruses in Kenyan bats and discovery of novel astroviruses, caliciviruses and rotaviruses. Virol Sin. 2017 Apr;32(2):101-114. doi: 10.1007/s12250-016-3930-2. Epub 2017 Apr 6. PubMed PMID: 28393313.