个人简历

受教育经历
1985.09-1989.06商洛地区卫校
1989.09-1991.07延安医学院，临床医学专业
1995.09-1998.07西安医科大学，获硕士学位
1998.09-2001.07年于第四军医大学，获医学博士学位
工作经历
2001.07-2016.11就职于温州医科大学附属眼视光医学
2016.12至今就职于河南省人民医院眼科

近期论文

[1] Yufei Wang1,†, Bang Wang1,†, Haihua Xie1, Qianwen Ren1, Xiexie Liu1, Fanfan Li2, Xiujuan Lv1, Xiubin He1, Congsheng Cheng2, Ruzhi Deng1, Jin Li1, Junzhao Zhao2, Zongming Song1,3,*(通讯), Feng Gu1,*(通讯).Efficient human genome editing using SaCas9 ribonucleoprotein complexes. Biotechnology Journal, 2019 Accepted.
[2] Zheng B, Chen Y, Chen L, Chen H, Zheng J, Chen F, Song Z, Fu L, Hu X, Pan J, Lian H, Shen L, Li Q. Comparative Study on the Efficacy and Safety of Tumor Resection in Vitrectomy for Retinal Vasoproliferative Tumors. J Ophthalmol. 2019 Jan 2;2019:7464123. doi: 10.1155/2019/7464123. eCollection 2019.
[3] Ju, X, Yang, X, Yan, T, Chen, H, Song Z，Zhang Z, Wu W，Wang, Y. EGFR inhibitor, AG1478, inhibits inflammatory infiltration and angiogenesis in mice with diabetic retinopathy. Clinical and Experimental Pharmacology and Physiology.2019, 46(1):75-85. (4 区, IF: 2.092)
[4] Lin L, He X, Zhao T, Gu L, Liu Y, Liu X, Liu H, Yang F, Tu M, Tang L, Ge X, Liu C, Zhao J, Song Z, Qu J, Gu F.Engineering the Direct Repeat Sequence of crRNA for Optimization of FnCpf1-Mediated Genome Editing in Human Cells. Mol Ther. 2018 Nov 7;26(11):2650-2657. doi: 10.1016/j.ymthe.2018.08.021. Epub 2018 Sep 1. IF 6.5858, JCR 1
[5] Wang L, Chen HC, Yang X, Tao JJ, Liang G, Wu JZ, Wu WC, Wang Y, Song ZM(通讯), Zhang XM(通讯). The novel chalcone analog L2H17 protects retinal ganglion cells from oxidative stress-induced apoptosis. Neural Regen Res 13(9):1665-1672. doi:10.4103/1673-5374.237140. IF 2.234, JCR 4
[6] Xuting Hu，Tianyu Chen, Zhongqiang Zhou, Zongduan Zhang, Zongming Song(通讯). Predictive clinical features and efficacy of preoperativeanti-VEGF treatment on visual acuity in patients with proliferative diabetic retinopathy. Int J Clin Exp Med 2018;11(7):7376-7383 IF 0.833，JCR 4
[7] Yang F, Ge X, He X, Liu X, Zhou C, Sun H, Zhang J, Zhao J, Song Z, Qu J, Liu C, Gu F. Functional non-homologous end joining patterns triggered by CRISPR/Cas9 in human cells. J Genet Genomics. 2018 May 8. pii: S1673-8527(18)30078-X. doi: 10.1016/j.jgg.2018.02.009. IF4.066， JCR 2
[8] Sun H, Li F, Liu J, Yang F, Zeng Z, Lv X, Tu M, Liu Y, Ge X, Liu C, Zhao J, Zhang Z, Qu J, Song Z, Gu F. A Single Multiplex crRNA Array for FnCpf1-Mediated Human Genome Editing. Mol Ther. 2018 Jun 15. pii: S1525-0016(18)30249-1. doi: 10.1016/j.ymthe.2018.05.021. IF 7.008， JCR 1
[9] Chen T, Su B, Chen Z, Tong J, Bedell H, Song Z(通讯), Zhang B(通讯).The associations among metamorphopsia, orientation discrimination threshold, and retinal layer thickness in patients with idiopathic epiretinal membrane. Curr Eye Res. 2018 May 26. doi: 10.1080/02713683.2018.1481515. [Epub ahead of print]. IF2.238, JCR 3
[10] Wang Y, Li H, Zang S, Li F, Chen Y, Zhang X, Song Z, Peng Q, Gu F. Photoreceptor Cell-Derived CAPN5 Regulates Retinal Pigment Epithelium Cell Proliferation Through Direct Regulation of SLIT2 Cleavage. Invest Ophthalmol Vis Sci. 2018 Apr 1;59(5):1810-1821. doi: 10.1167/iovs.17-22689. IF3.303， JCR 2
[11] Chen H, Song Z(并列第一), Ying S, Yang X, Wu W, Tan Q, Ju X, Wu W, Zhang X, Qu J, Wang Y. Myeloid differentiation protein 2 induced retinal ischemia reperfusion injury via upregulation of ROS through a TLR4-NOX4 pathway.Toxicol Lett. 2018 Jan 5;282:109-120. doi: 10.1016/j.toxlet.2017.10.018. Epub 2017 Oct 27.IF 3.858, JCR 2
[12] Ding Chen, Tao Xu，Mengjun Tu,Jinlin Xu, Chenchen Zhou, Lulu Cheng, Ruqing Yang, Tanchu Yang, Weiwei Zheng, Xiubin He, Ruzhi Deng, Xianglian Ge, Jin Li,Zongming Song, Junzhao Zhao, and Feng Gu. Recapitulating X-Linked Juvenile Retinoschisis in Mouse Model by Knock-In Patient-Specific Novel Mutation. Front Mol Neurosci. 2017; 10: 453.Published online 2018 Jan 12. doi: 10.3389/fnmol.2017.00453. IF 5.076，JCR2
[13] Lei Lei, Xianglian Li, Taotao Xiong, Jing Yu, Xinxin Yu, Zongming Song(通讯), Xingyi Li(通讯). Covalently Cross-Linked Chitosan Hydrogel Sheet for Topical Ophthalmic Delivery of Levofloxacin. J. Biomed. Nanotechnol. 2018, (14)371–378.IF 4.521, JCR 2
[14] Xie H, Tang L, He X, Liu X, Zhou C, Liu J, Ge X, Li J, Liu C, Zhao J, Qu J, Song Z(通讯), Gu F(通讯). SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells. Biotechnol J. 2017 Dec 16. doi: 10.1002/biot.201700561. IF 3.649,JCR2
[15] Mengjun Tu, Li Lin, Yilu Cheng, Xiubin He, Huihui Sun, Haihua Xie, Junhao Fu, Changbao Liu, JinLi, Ding Chen, Haitao Xi, Dongyu Xue, Qi Liu, Junzhao Zhao, Caixia Gao, Zongming Song, Jia Qu , Feng Gu. A ‘new lease of life’: FnCpf1 possesses DNA cleavage activity for genome editing in human cells. Nucleic Acids Research, 2017， 1，doi: 10.1093/nar/gkx783. IF 10.162. JCR 1
[16] Yan Wang, Xiao Zhang, Zongming Song, Feng Gu. An anti-CAPN5 intracellular antibody acts as an inhibitor of CAPN5-mediated neuronal degeneration. Oncotarget. 2017 Nov 1;8(59):100312-100325. doi: 10.18632/oncotarget.22221. eCollection 2017 Nov 21. IF 5.168, JCR 2
[17] Huiqiong Chen, Tangbing Liu, Zhenhai Zeng, Yufei Wang, Yuanyuan Lin, Lulu Cheng, Qintuo Pan, Feng Gu(通讯), Zongming Song(通讯), Zongduan Zhang. Clinical characteristics of a KIF21A mutation in a Chinese family with congenital fibrosis of the extraocular muscles type1. Medicine (Baltimore)2017Sep;96(38): e8068.IF 1.803,JCR3
[18] Ren L, Tao J, Chen H, Bian Y, Yang X, Chen G, Zhang X, Liang G, Wu W, Song Z(通讯), Wang Y(通讯). Myeloid differentiation protein 2-dependent mechanisms in retinal ischemia-reperfusion injury.Toxicol Appl Pharmacol. 2017 Feb 15;317:1-11. doi: 10.1016/j.taap.2017.01.001. Epub 2017 Jan 4. IF 3.791，JCR 2
[19] Fayu Yang, Changbao Liu, Ding Chen, Mengjun Tu, Haihua Xie, Huihui Sun, Xianglian Ge, Lianchao Tang, Jin Li, Jiayong Zheng, Zongming Song, Jia Qu, Feng Gu. CRISPR/Cas9-loxP-Mediated Gene Editing as a Novel Site-Specific Genetic Manipulation Tool. Mol Ther Nucleic Acids. 2017 Jun 16; 7: 378–386. 2017 Apr 25. doi: 10.1016/j.omtn. 2017.04.018. IF 6.392，JCR 2.
[20] Lin Z, Ke ZS, Zheng Q, Zhao ZQ, Song ZM. Passive Removal of Silicone Oil with Temporal Head Position through Two 23-Gauge Cannulas. J Ophthalmol. 2016;2016:4182693. doi: 10.1155/2016/4182693. Epub 2016 Jun 22. IF 1.712, JCR 4
中华医学会眼科分会委员，眼科专家会员、中华医学会眼科分会眼底病学组委员、中国医师协会眼科常委、眼外伤学组委员；国家防盲技术指导专家、河南省防盲技术指导组组长；河南省医学会眼科分会侯任主委、河南省医师协会眼科分会会长；中文核心期刊《中华眼底病杂志》编委等