个人简历

Dr. Bing Guo’s research was mainly focused on aggregation-induced emission materials and conjugated polymers for biomedical and energy applications. He contributed to advanced molecular imaging and treatment technologies for brain diseases by developing functional optical sensors in the second near-infrared window, for which he was awarded a “CSC Scholarship for Outstanding Self-financed Student Abroad” in year 2019.

Recruitment of Post-Doctors in Laboratory of Molecular Engineering
(i) The candidate should be younger than 35-year old, and has no more than 3-year work experience since PhD graduation.
(ii) The promising candidate should have at least one of the following backgrounds, which include organic dyes, polymers, drug delivery systems, immunotherapy, cell culture, animal study and etc.
(iii) The salary is negotiable and starts from 320,000 RMB annually.
If interested, please send your CV and publications to mailbox
研究与工作经历
2020-至今，哈尔滨工业大学(深圳) 理学院， 副教授
2018-2019，新加坡国立大学，博士后
2014-2018，新加坡国立大学，化学与生物分子工程系，博士
2011-2014，香港理工大学，纺织与制衣系，哲学硕士
2010-2011，北京化工大学，化学专业，硕士学习
2008-2010，中科院宁波材料技术与工程研究所，研究助理
2004-2008，郑州大学，高分子材料与工程专业，本科

研究领域

分子工程实验室的主要研究方向：
1．分子影像。针对脑疾病（脑肿瘤和神经退化疾病），心血管疾病，耐药菌，肿瘤等，设计分子影像探针，实现疾病的早期诊断和精准治疗。努力推进近红外（NIR-II）荧光的小分子影像探针的临床转化。
使用多学科知识和技术（有机化学、高分子、药学、生物医学、纳米技术、先进（荧光、光声、核磁、多模态等）影像技术），着重提高多尺度成像的质量（灵敏度、分辨率、深度和信噪比）和各种治疗方法（化疗、光动力、光热、免疫治疗等）的疗效，推进转化医学的进步。
2. 前药、药物递送高分子。纳米药物和制剂的设计、稳定制备与临床转化。
3.智能材料与器件：小分子和高分子的有机发光二极管材料与器件(OLED,PLED)、柔性电子器件、光电检测器、有机半导体激光、热电高分子、光/热控形变高分子、力致变色材料、磷光材料、动态荧光防伪材料、体外检测材料等。
4. 高分子树脂，纤维-树脂复合材料
5. 能源材料：例如用于固态锂电池的聚电解质，光/电催化材料，电子/空穴传输材料。""

近期论文

[14] Bing Guo, Min Wu, Qi Shi, Tianjiao Dai, Shidang Xu, Jianwen Jiang, Bin Liu, All-in-One Molecular AIE Theranostics: Fluorescence Image Guided and Mitochondria Targeted Chemo- and Photodynamic Cancer Cell Ablation, Chem. Mater. 2020, 32, 4681-4691. (IF = 9.567)
Before joining HIT
[13] Bing Guo, Zemin Huang, Qi Shi, Eshu Middha, Shidang Xu, Ling Li, Min Wu, Jianwen Jiang, Qinglian Hu, Zhengwei Fu, Bin Liu, Organic Small Molecule Based Photothermal Agents with Molecular Rotors for Malignant Breast Cancer Therapy, Adv. Funct. Mater. 2020, 30, 1907093. (IF = 16.836)
[12] Yukun Duan, Dehong Hu, Bing Guo (co-first author), Qi Shi, Min Wu, Shidang Xu, Kenry, Xin Liu, Jianwen Jiang, Zonghai Sheng, Hairong Zheng, Bin Liu, Nanostructural Control Enables Optimized Photoacoustic-Fluorescence-Magnetic Resonance Multimodal Imaging and Photothermal Therapy of Brain Tumor, Adv. Funct. Mater. 2020, 30, 1907077. (IF = 16.836)
[11] Bing Guo, Zhe Feng, Dehong Hu, Shidang Xu, Eshu Middha, Yutong Pan, Chengbo Liu, Hairong Zheng, Jun Qian, Zonghai Sheng, Bin Liu, Precise Deciphering of Brain Vasculatures and Microscopic Tumors with Dual NIR-II Fluorescence and Photoacoustic Imaging, Adv. Mater. 2019, 31,1902504. (IF = 27.398)
[10] Bing Guo, Jingqin Chen, Ningbo Chen, Eshu Middha, Shidang Xu, Yutong Pan, Min Wu, Ke Li, Chengbo Liu, Bin Liu, High-Resolution 3D NIR-II Photoacoustic Imaging of Cerebral and Tumor Vasculatures Using Conjugated Polymer Nanoparticles as Contrast Agent, Adv. Mater. 2019, 31, 1808355. (IF = 27.398)
[9] Bing Guo, Eshu Middha, Bin Liu, Solvent Magic for Organic Particles, ACS Nano 2019, 13, 2675-2680. (IF = 14.588)
[8] Zhe Wang, Bing Guo (co-first author), Eshu Middha, Zeming Huang, Qinglian Hu, Zhengwei Fu, and Bin Liu, Microfluidics-Prepared Uniform Conjugated Polymer Nanoparticles for Photo-Triggered Immune Microenvironment Modulation and Cancer Therapy, ACS Appl. Mater. Interface 2019, 11, 11167-11176. (IF = 8.456)
[7] Haibin Yu, Bing Guo (co-first author), Hequn Zhang, Jing Zhou, Xiaoming Yu, Liang Zhu, Dingwei Xue, Wen Liu, Xianhe Sun, Jun Qian, NIR-II Fluorescence in vivo Confocal Microscopy with Aggregation-Induced Emission Dots, Sci. Bull. 2019, 64, 410-416 ( Cover). (IF = 9.511)
[6] Bing Guo, Zonghai Sheng, Dehong Hu, Chengbo Liu, Hairong Zheng, Bin Liu, Through Scalp and Skull NIR-II Photothermal Therapy of Deep Orthotopic Brain Tumors with Precise Photoacoustic Imaging Guidance, Adv. Mater. 2018, 30, 1802591 (ESI Highly Cited).(IF = 27.398)
[5] Zonghai Sheng, Bing Guo (co-first author), Dehong Hu, Shidang Xu, Wenbo Wu, Weng Heng, Liew Kui Yao, Jingying Jiang, Chengbo Liu, Hairong Zheng, Bin Liu, Bright AIE Dots for Targeted Synergetic NIR-II Fluorescence and NIR-I Photoacoustic Imaging of Orthotopic Brain Tumor, Adv. Mater. 2018, 30, 1800766, VIP paper, Cover (ESI Highly Cited) (IF = 27.398).
[4] Bing Guo, Zonghai Sheng, Dehong Hu, Anran Li, Shidang Xu, Purnima Naresh Manghnani, Chengbo Liu, Lin Guo, Hairong Zheng, Bin Liu, Molecular Engineering of Conjugated Polymers for Biocompatible Organic Nanoparticles with Highly Efficient Photoacoustic and Photothermal Performance in Cancer Theranostics, ACS Nano 2017, 11, 10124-10134. (IF = 14.588)
[3] Bing Guo, Zonghai Sheng, Kenry, Dehong Hu, Xiangwei Lin, Shidang Xu, Chengbo Liu, Hairong Zheng, Bin Liu, Biocompatible Conjugated Polymer Nanoparticles for Highly Efficient Photoacoustic Imaging of Orthotopic Brain Tumor in Second Near-Infrared Window, Mater. Horiz. 2017, 4, 1151-1156. (IF = 12.319)
[2] Bing Guo, Guangxue Feng, Purnima Naresh Manghnani, Xiaolei Cai, Jie Liu, Wenbo Wu, Shidang Xu, Xiamin Cheng, Cathleen Teh, Bin Liu, A Porphyrin‐Based Conjugated Polymer for Highly Efficient In Vitro and In Vivo Photothermal Therapy, Small 2016, 12, 6243-6254. (IF = 11.459)
[1] Bing Guo, Xiaolei Cai, Shidang Xu, Syed Mohammad Ali Fateminia, Jie Liu, Jing Liang, Guangxue Feng, Wenbo Wu, Bin Liu, Decoration of Porphyrin with Tetraphenylethene: Converting a Fluorophore with Aggregation-Caused Quenching to Aggregation-Induced Emission Enhancement, J. Mater. Chem. B 2016, 4, 4690-4695. (IF = 5.344)